{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:27:38Z","timestamp":1777890458605,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2020,11,27]]},"abstract":"<jats:p>BACKGROUND: Stridor is one of the rare side effects of neonatal hypothermia treatment for hypoxic-ischemic encephalopathy. We aimed to describe the clinical characteristics of the infants who underwent whole-body hypothermia and developed stridor. METHODS: We reviewed the medical records of 171 infants with moderate or severe hypoxic-ischemic encephalopathy who underwent hypothermia therapy. Demographics, as well as clinical characteristics, were documented. RESULTS: A total of 18 infants developed transient stridor out of 171 infants who underwent whole-body hypothermia (10.5%). The stridor was transient and resolved in all infants. All infants with stridor received treatment with one or more of the following: racemic epinephrine, dexamethasone, positive pressure ventilation and\/or heliox. Two infants required otorhinolaryngologist (ENT) evaluation due to persistent and severe symptoms, of whom one was found to have left vocal cord paresis that improved with time. CONCLUSION: Stridor is a transient complication associated with hypoxic-ischemic encephalopathy and whole-body hypothermia in neonates. The exact mechanism is unclear and most likely multifactorial. ENT evaluation is recommended in the presence of prolonged symptoms or significant respiratory distress.<\/jats:p>","DOI":"10.3233\/npm-190332","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T12:40:49Z","timestamp":1579610449000},"page":"463-468","source":"Crossref","is-referenced-by-count":2,"title":["Stridor in infants with hypoxic-ischemic encephalopathy and whole body hypothermia: A case series"],"prefix":"10.1177","volume":"13","author":[{"given":"M.","family":"Alsaleem","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Children\u2019s Mercy Hospital, Kansas City, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Hpa","sequence":"additional","affiliation":[{"name":"Neonatal-Perinatal Medicine, The State University of New York, University at Buffalo, Buffalo, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.H.S.","family":"Kumar","sequence":"additional","affiliation":[{"name":"Division of Neonatal-Perinatal Medicine, The State University of New York, University at Buffalo, Buffalo, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"6","key":"10.3233\/NPM-190332_ref1","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1542\/peds.2014-0899","article-title":"Hypothermia and neonatal encephalopathy","volume":"133","author":"Papile","year":"2014","journal-title":"Pediatrics"},{"issue":"6","key":"10.3233\/NPM-190332_ref2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/jp.2010.146","article-title":"Physiologic and pharmacologic considerations for hypothermia therapy in neonates","volume":"31","author":"Zanelli","year":"2011","journal-title":"J 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