{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:27:51Z","timestamp":1777890471933,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T00:00:00Z","timestamp":1590451200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2021,2,4]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Children with perinatal chronic lung disease (CLD) are at elevated risk for severe respiratory syncytial virus (RSV) disease in the first two years of life. The American Academy of Pediatrics policy does not recommend RSV immunoprophylaxis for infants with CLD born at \u226532 weeks\u2019 gestational age (wGA). The objective of this study was to describe the number and clinical characteristics of US infants in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Birth hospitalization data from the Kids\u2019 Inpatient Database were utilized to estimate the prevalence of CLD (International Classification of Diseases, Ninth Revision [ICD-9]\u200a=\u200a770.7) in 2003-2012 overall and by gestational age (ICD-9\u200a=\u200a765.21\u2013765.29). CLD birth hospitalizations were evaluated by length of stay, costs, ventilatory support, and inpatient mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>A total of 33,537 infants were diagnosed with CLD, representing 0.2% of US births; 79% had wGA coded in the database. Among infants with CLD with wGA, 3.5% were born at &gt;32 wGA, representing 7 of every 100,000 US births, or approximately 300 infants annually. Across all wGA categories, birth hospitalization length of stay and costs were elevated, and mechanical ventilation use ranged from 73% to 97%. All-cause inpatient mortality was highest among those &lt;27 wGA and &gt;32 wGA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Approximately 300 infants born at &gt;32 wGA are diagnosed with CLD annually in the United States. The all-cause perinatal mortality rate is high in this population. The rationale for excluding this small but high-risk group of infants from the recommendations for RSV immunoprophylaxis is unclear.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-200412","type":"journal-article","created":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T11:14:58Z","timestamp":1590491698000},"page":"43-51","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and clinical characteristics of perinatal chronic lung disease by infant gestational age"],"prefix":"10.1177","volume":"14","author":[{"given":"K.","family":"Mavunda","sequence":"first","affiliation":[{"name":"Kidz Medical Services, Coral Gables, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Jiang","sequence":"additional","affiliation":[{"name":"EpidStat Institute, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.S.","family":"Ambrose","sequence":"additional","affiliation":[{"name":"AstraZeneca, Gaithersburg, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,5,26]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-017-2849-4"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1007\/s001340050599"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1542\/peds.86.5.728"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.3.531"},{"key":"ref005","unstructured":"Healthcare Cost and Utilization Project (HCUP) [Internet]. Rockville, MD: Agency for Healthcare Research and Quality; [cited 2019 Dec 26]. Available from: www.hcup-us.ahrq.gov\/kidoverview.jsp."},{"key":"ref006","unstructured":"U.S. Bureau of Labor Statistics [Internet]. Washington, DC; [cited 2019 Dec 26]. Available from: http:\/\/www.bls.gov\/data\/inflation_calculator.htm."},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1371\/jour-nal.pone.0152208"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-1665"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-1381"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.11.003"},{"key":"ref011","unstructured":"Institute of Medicine (US) Committee on Understanding Premature Birth and Assuring Healthy Outcomes. Mortality and acute complications in preterm infants. In: Behrman RE, Butler AS, editors. Preterm birth: causes, consequences, and prevention. Washington, DC: National Academies Press; 2007. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK11385\/."},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2952"},{"issue":"7","key":"ref013","first-page":"843","volume":"284","author":"Kramer MS","year":"2000","journal-title":"Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System. JAMA"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.02.002"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.07.015"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.02.003"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.2.372"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1053\/sp.2000.6364"},{"key":"ref019","unstructured":"MillerMJ, FanaroffAA, MartinRJ. The respiratory system. Part 5: Respiratory disorders in pretermand terminfants. In: Martin RJ, Fanaroff AA, Walsh MC, editors. Fanaroff and Martin\u2019s Neonatal-Perinatal Medicine. 8th ed. Philadelphia, PA: Mosby Elsevier; 2006. p. 1122-46."},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.4.775"},{"key":"ref021","unstructured":"ZahkaKG. The cardiovascular system. Part 4: Principles of neonatal cardiovascular hemodynamics. In: Martin RJ, Fanaroff AA, Walsh MC, editors. Fanaroff and Martin\u2019s neonatal perinatal medicine. 8th ed. Philadelphia, PA: Mosby Elsevier; 2006. p. 1211-5."},{"key":"ref022","first-page":"1071","volume-title":"Avery\u2019s diseases of the newborn","author":"Beserth CL","year":"2005","edition":"8"},{"key":"ref023","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.09.022"},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1159\/000381361"},{"key":"ref025","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23235"},{"key":"ref026","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.06.089"},{"key":"ref027","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000464"},{"key":"ref028","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-018-03308-1"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-200412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-200412","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-200412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:38:29Z","timestamp":1777613909000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-200412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,26]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2,4]]}},"alternative-id":["10.3233\/NPM-200412"],"URL":"https:\/\/doi.org\/10.3233\/npm-200412","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,26]]}}}