{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:40:36Z","timestamp":1782258036467,"version":"3.54.5"},"reference-count":35,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2022,1,27]]},"abstract":"<jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Few studies exist that research the association between umbilical cord characteristics with cardiac malformations. In this study, we describe a population of newborns with congenital heart defects (CHD) and the frequency of presentation of umbilical cord (UC) alterations, based upon the hypothesis that the continuity of the cardio-placental circuit can be affected by similar noxas during early development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We carried out a descriptive study at a hospital in Bogota based on clinical records from newborns with congenital heart disease with placental and UC pathology results. Group analyses were done according to the major categories of the ICD-10.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>We analyzed 122 cases and found that the most frequent alterations where hypercoiling (27.9%) and abnormal UC insertion (16.4%). Additionally, in almost every group of CHD, more than 65%of patients had some type of cord alteration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>We discovered a high frequency of UC alterations in patients with CHD. This outcome suggests that a possible association exists between the two phenomena, further research is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-210799","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T12:56:18Z","timestamp":1631883378000},"page":"81-88","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Congenital heart defects and umbilical cord abnormalities, an unknown association?"],"prefix":"10.1177","volume":"15","author":[{"given":"L.P.","family":"Monta\u00f1a-Jimenez","sequence":"first","affiliation":[{"name":"Hospital Universitario San Ignacio, Bogot\u00e1 D.C, Colombia"},{"name":"Pontificia Universidad Javeriana, Bogot\u00e1 D.C, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Lasalvia","sequence":"additional","affiliation":[{"name":"Neuroeconomix, Bogot\u00e1 D.C, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Diaz Puentes","sequence":"additional","affiliation":[{"name":"Hospital Universitario San Ignacio, Bogot\u00e1 D.C, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Olaya-C","sequence":"additional","affiliation":[{"name":"Hospital Universitario San Ignacio, Bogot\u00e1 D.C, Colombia"},{"name":"Pontificia Universidad Javeriana, Bogot\u00e1 D.C, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.18597\/rcog.8"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2007.02.004"},{"key":"ref003","unstructured":"Fr\u00edasJ G-BE. Disruptions. In: Gilbert-Barness E Potte's pathology of the fetus, infant and child Second edition Vol 1. Mosby Elsevier; 2007;135\u2013212."},{"key":"ref004","unstructured":"BaergenRN. Pathology of the umbilical cord. In: Manual of and Kaufmann\u2019s pathology of the human placenta. New York: New York Springfield; 2005;249\u201376."},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.06.001"},{"issue":"1","key":"ref006","first-page":"113","volume":"29","author":"Gilbert-Barness E","year":"1993","journal-title":"Birth Defects Orig Artic Ser"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.2350\/09-07-0680-CR.1"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2004.02.014"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2014.00390"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.00373"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00600.2013"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2013.05.003"},{"issue":"1","key":"ref013","first-page":"37","volume":"3","author":"N\u00fa\u00f1ez-Pati\u00f1o R","year":"2017","journal-title":"Salut Sci Spiritus"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5373.108"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.68.040104.113828"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-11-0636"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S174734"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.128777"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2015.06.013"},{"issue":"4","key":"ref020","first-page":"262","volume":"39","author":"Benirschke K","year":"1994","journal-title":"J Reprod Med"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00715-4"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61135-1"},{"key":"ref023","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60194-5"},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61305-2"},{"key":"ref025","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000429658.85846.f9"},{"key":"ref026","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-016-0950-9"},{"key":"ref027","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2018.12.001"},{"key":"ref028","first-page":"141","volume":"38","author":"Tassinari S","year":"2018","journal-title":"Biom\u00e9dica"},{"key":"ref029","doi-asserted-by":"publisher","DOI":"10.1177\/1093526618758204"},{"key":"ref030","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5180"},{"key":"ref031","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0078-y"},{"key":"ref032","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.741153"},{"key":"ref033","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12494"},{"key":"ref034","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-019-02189-x"},{"key":"ref035","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5177"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-210799","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-210799","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-210799","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:41:51Z","timestamp":1777614111000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-210799"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,17]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1,27]]}},"alternative-id":["10.3233\/NPM-210799"],"URL":"https:\/\/doi.org\/10.3233\/npm-210799","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,17]]}}}