{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:34:05Z","timestamp":1788582845286,"version":"build-2803163510"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2022,12,23]]},"abstract":"<jats:p>There are multiple manifestations in the neonatal period for infants born to mothers with systematic lupus erythematosus (SLE), ranging from cardiac, hematologic and dermatologic abnormalities. Cardiac complications may arise in utero in the form of heart block with a resulting increase in fetal mortality. The fetal conduction system is suspected to be affected by transplacental maternal antibodies, however additional environmental and fetal factors appear to play a role. We describe a rare case of a dichorionic-diamniotic twin pregnancy in which only one twin developed a complete heart block progressing to hydrops fetalis and fetal demise.<\/jats:p>","DOI":"10.3233\/npm-210819","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T13:27:37Z","timestamp":1650979657000},"page":"863-866","source":"Crossref","is-referenced-by-count":1,"title":["Discordant expression of maternal SLE in twin pregnancy with a single fetal AV block: A case report"],"prefix":"10.1177","volume":"15","author":[{"given":"M.Q.","family":"Mehdi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"Franco Fuenmayor","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, University of Texas Medical Branch, Galveston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Aly","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Cardiology, University of Texas Medical Branch, Galveston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"issue":"10","key":"10.3233\/NPM-210819_ref1","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1191\/0961203303lu466ed","article-title":"Congenital heart block: Do fetal factors fuel the fire from inflammation to fibrosis?","volume":"12","author":"Buyon","year":"2003","journal-title":"Lupus"},{"issue":"18","key":"10.3233\/NPM-210819_ref2","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1161\/CIRCULATIONAHA.111.033894","article-title":"Maternal and fetal factors associated with mortality and morbidity in a multi\u2013racial\/ethnic registry of anti-SSA\/Ro\u2013associated cardiac neonatal lupus","volume":"124","author":"Izmirly","year":"2011","journal-title":"Circulation"},{"issue":"8","key":"10.3233\/NPM-210819_ref3","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.jogoh.2019.05.002","article-title":"Discordant immune complete heart block and growth restriction in dichorionic twin pregnancy with permanent pacemaker implantation of an g neonate","volume":"48","author":"Envain","year":"2019","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"3","key":"10.3233\/NPM-210819_ref4","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s12016-017-8653-0","article-title":"Neonatal systemic lupus erythematosus syndrome: A comprehensive review","volume":"53","author":"Vanoni","year":"2017","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.3233\/NPM-210819_ref5","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1016\/S0735-1097(98)00161-2","article-title":"Autoimmune-associated congenital heart block: Demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry","volume":"31","author":"Buyon","year":"1998","journal-title":"J Am Coll Cardiol"},{"issue":"16","key":"10.3233\/NPM-210819_ref6","first-page":"E671","article-title":"Perinatal outcome of fetal atrioventricular block: One-hundred-sixteen cases from a single institution (vol 118, pg 1268, 2008)","volume":"118","author":"Lopes","year":"2008","journal-title":"Circulation."},{"key":"10.3233\/NPM-210819_ref7","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1365-2133.1994.tb02931.x","article-title":"Neonatal lupus erythematosus. 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