{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:30:24Z","timestamp":1777890624824,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2022,4,12]]},"abstract":"<jats:p>BACKGROUND: COVID-19 disease can affect women at any stage of pregnancy, and newborns could become infected with SARS-CoV-2 through vertical or horizontal transmission. Little is known about SARS-CoV-2 infection in neonates born to mothers with COVID-19. Experts emphasize the importance of ensuring the safety of newborns without compromising the benefits of early contact with the mother. The aim of the study was to investigate the epidemiological characteristics of newborns born to mothers infected with SARS-CoV-2. METHODS: Observational, prospective cohort study was conducted in the intensive care unit of the perinatal center (Georgia). Information was collected by reviewing and personal observations of medical histories of newborns born to mothers infected with SARS-CoV-2. RESULTS: The study included 38 newborns with suspected (n\u200a=\u200a16; 42.1%) and confirmed (n\u200a=\u200a22; 57.9%) COVID-19 infection cases, treated in the neonatal intensive care unit. The study did not reveal the risk of vertical transmission of SARS-CoV-2 infection and confirmed a fairly large rate of horizontal transmission of infection (n\u200a=\u200a25; 66%). Skin-to-skin mother care was performed in 68.7% of newborns, 26.3% received exclusive maternal or donated breast milk during hospital stay. CONCLUSION: Prevention of horizontal transmission of infection in newborns should be a priority. It is recommended skin-to-skin mother care and maternal or donated breast milk during hospital stay, taking into account the health of the mother and the newborn, following the rules of hygiene and use of the mask by the infected mother.<\/jats:p>","DOI":"10.3233\/npm-210883","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T11:52:18Z","timestamp":1642161138000},"page":"291-295","source":"Crossref","is-referenced-by-count":1,"title":["Epidemiological characteristics of neonates born to mothers infected with COVID-19: A single-centre observational study"],"prefix":"10.1177","volume":"15","author":[{"given":"T.","family":"Verulava","sequence":"first","affiliation":[{"name":"School of Medicine and Healthcare Management, Caucasus University, Tbilisi, Georgia"},{"name":"Faculty of Health Care Economics and Management, Teaching University Geomedi, Tbilisi, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Galogre","sequence":"additional","affiliation":[{"name":"School of Medicine and Healthcare Management, Caucasus University, Tbilisi, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/NPM-210883_ref1","unstructured":"World Health Organization. WHO Director-General\u2019s opening remarks at the media briefing on COVID-19 - 11 March 2020. Available at: https:\/\/www.who.int\/dg\/speeches\/detail\/who-director-general-s-opening-remarksat-the-media-briefing-on-covid-19\u201411-march-2020."},{"key":"10.3233\/NPM-210883_ref2","first-page":"e50","article-title":"Clinical characteristics of COVID-19 infection in newborns and pediatrics: A systematic review","volume":"8","author":"Panahi","year":"2020","journal-title":"Arch Acad Emerg Med"},{"issue":"4","key":"10.3233\/NPM-210883_ref3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3233\/NPM-200489","article-title":"A newborn with coronavirus (COVID-19) disease: A brief report","volume":"13","author":"Rong","year":"2020","journal-title":"J Neonatal-Perinatal Med"},{"key":"10.3233\/NPM-210883_ref4","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ajog.2020.04.024","article-title":"Screening all pregnant women admitted to labor and delivery for the virus responsible for coronavirus disease","volume":"223","author":"Vintzileos","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.3233\/NPM-210883_ref5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.21037\/tp.2020.02.06","article-title":"Clinical analysis of 10 neonates born to mothers with -nCoV pneumonia","volume":"9","author":"Zhu","year":"2020","journal-title":"Transl Pediatr"},{"issue":"2","key":"10.3233\/NPM-210883_ref6","doi-asserted-by":"crossref","first-page":"423","DOI":"10.21037\/tp-20-144","article-title":"Is there possibility of vertical transmission of COVID- A systematic review","volume":"10","author":"Yuan","year":"2021","journal-title":"Transl Pediatr"},{"issue":"8","key":"10.3233\/NPM-210883_ref7","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1055\/s-0040-1710050","article-title":"Severe COVID-19 during pregnancy and possible vertical transmission","volume":"37","author":"Alzamora","year":"2020","journal-title":"Am J Perinatol"},{"key":"10.3233\/NPM-210883_ref8","doi-asserted-by":"crossref","first-page":"3572","DOI":"10.1038\/s41467-020-17436-6","article-title":"Transplacental transmission of SARS-CoV-2 infection","volume":"11","author":"Vivanti","year":"2020","journal-title":"Nat Commun"},{"issue":"5","key":"10.3233\/NPM-210883_ref9","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1542\/neo.21-5-e293","article-title":"Neonatal management during the coronavirus disease (COVID-19) outbreak: The Chinese experience","volume":"21","author":"Ma","year":"2020","journal-title":"NeoReviews.e"},{"issue":"3","key":"10.3233\/NPM-210883_ref10","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1080\/15513815.2020.1747120","article-title":"Vertical transmission of coronavirus disease 19 (COVID-19) from infected pregnant mothers to neonates: A review","volume":"39","author":"Karimi-Zarchi","year":"2020","journal-title":"Fetal Pediatr Pathol"},{"issue":"8","key":"10.3233\/NPM-210883_ref11","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1055\/s-0040-1710050","article-title":"Severe COVID-19 during pregnancy and possible vertical transmission","volume":"37","author":"Alzamora","year":"2020","journal-title":"Am J Perinatol"},{"issue":"18","key":"10.3233\/NPM-210883_ref12","first-page":"1846","article-title":"Possible vertical transmission of SARSCoV-2 from an infected mother to her newborn","volume":"323","author":"Dong","year":"2020","journal-title":"JAMA"},{"issue":"3","key":"10.3233\/NPM-210883_ref13","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3233\/NPM-200478","article-title":"Management of the mother-infant dyad with suspected or confirmed SARS-CoV-2 infection in a highly epidemic context\u2019","volume":"13","author":"Pietrasanta","year":"2020","journal-title":"J. Neonatal Perinat. Med"},{"issue":"3","key":"10.3233\/NPM-210883_ref14","doi-asserted-by":"crossref","first-page":"e13010","DOI":"10.1111\/mcn.13010","article-title":"Breastfeeding and coronavirus disease-Ad interim indications of the Italian Society of Neonatology endorsed by the Union of European Neonatal & Perinatal Societies","volume":"16","author":"Davanzo","year":"2020","journal-title":"Matern Child Nutr"},{"key":"10.3233\/NPM-210883_ref15","unstructured":"World Health Organization. Breastfeeding advice during the COVID-19 outbreak. http:\/\/www.emro.who.int\/nutrition\/nutrition-infocus\/breastfeeding-advice-during-covid-19-outbreak.html (2020)."},{"issue":"1","key":"10.3233\/NPM-210883_ref16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s13006-020-00314-8","article-title":"Breastfeeding mothers with COVID-19 infection: A case series","volume":"15","author":"Pereira","year":"2020","journal-title":"Int Breastfeed J"},{"issue":"10","key":"10.3233\/NPM-210883_ref17","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1038\/s41372-020-0765-3","article-title":"Newborns of COVID-19 mothers: Short-term outcomes of colocating and breastfeeding from the pandemic\u2019s epicenter","volume":"40","author":"Patil","year":"2020","journal-title":"J Perinatol"},{"issue":"4","key":"10.3233\/NPM-210883_ref18","doi-asserted-by":"crossref","first-page":"128","DOI":"10.15406\/jpnc.2020.10.00427","article-title":"Clinical profile of neonates delivered from mothers with confirmed COVID-19 infection: An experience from a Tertiary Perinatal Care Center in Dubai, UAE","volume":"10","author":"Saleh Elhalik","year":"2020","journal-title":"J Pediatr Neonatal Care"},{"key":"10.3233\/NPM-210883_ref19","first-page":"405","article-title":"Evaluation of rooming-in practice for neonates born to mothers with severe acute respiratory syndrome coronavirus 2 infection in Italy","volume":"4","author":"Ronchi","year":"2020","journal-title":"JAMA Pediatr"},{"key":"10.3233\/NPM-210883_ref20","first-page":"2","article-title":"Sars-COV-2 in human breast milk and neonatal outcome","volume":"61","author":"Bertino","year":"2020","journal-title":"Lancet"},{"issue":"5","key":"10.3233\/NPM-210883_ref21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1631\/jzus.B2000095","article-title":"Can SARS-CoV-2-infected women breastfeed after viral clearance?","volume":"21","author":"Jing","year":"2020","journal-title":"J Zhejiang Univ Sci B"},{"issue":"05","key":"10.3233\/NPM-210883_ref22","first-page":"1","article-title":"Insight from a COVID-19-infected lactating mother with a healthy breastfed infant","volume":"01","author":"Feng","year":"2020","journal-title":"Front Med Case Rep"},{"key":"10.3233\/NPM-210883_ref23","first-page":"1846","article-title":"Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn","volume":"323","author":"Dong","year":"2020","journal-title":"JAMA"},{"key":"10.3233\/NPM-210883_ref24","doi-asserted-by":"crossref","first-page":"E647","DOI":"10.1503\/cmaj.200821","article-title":"Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection","volume":"192","author":"Kirtsman","year":"2020","journal-title":"CMAJ"},{"issue":"1","key":"10.3233\/NPM-210883_ref25","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ajog.2020.07.049","article-title":"Vertical transmission of coronavirus disease A systematic review and meta-analysis","volume":"224","author":"Kotlyar","year":"2021","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.3233\/NPM-210883_ref26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1001\/jamapediatrics.2020.4298","article-title":"Outcomes of Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection at a Large Medical Center in New York City","volume":"175","author":"Dumitriu","year":"2021","journal-title":"JAMA Pediatr"},{"key":"10.3233\/NPM-210883_ref27","doi-asserted-by":"crossref","first-page":"5164","DOI":"10.1038\/s41467-020-18982-9","article-title":"Synthesis and systematic review of reported neonatal SARS-CoV-2 infections","volume":"11","author":"Raschetti","year":"2020","journal-title":"Nat Commun"},{"key":"10.3233\/NPM-210883_ref28","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/ijgo.13146","article-title":"Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection","volume":"149","author":"Chen","year":"2020","journal-title":"Int. J. Gynaecol. Obstet"},{"key":"10.3233\/NPM-210883_ref29","doi-asserted-by":"crossref","unstructured":"Vivanti AJ , Deruelle P , Picone O , Guillaume S , Roze JC , Mulin B . Post-natal follow-up for women and neonates during the COVID-19 pandemic: French National Authority for Health recommendations. J Gynecol Obstet. Hum. Reprod. 2020;49(7).","DOI":"10.1016\/j.jogoh.2020.101805"},{"key":"10.3233\/NPM-210883_ref30","doi-asserted-by":"crossref","unstructured":"Tscherning C , Sizun J , Kuhn P . Promoting attachment between parents and neonates despite the COVID-19 pandemic. Acta Paediatr. 2020.","DOI":"10.1111\/apa.15455"},{"key":"10.3233\/NPM-210883_ref31","doi-asserted-by":"crossref","unstructured":"Merewood A , Davanzo R , Haas-Kogan M , Vertecchi G , Gizzi C , Mosca F , Burnham L , Moretti C . Breastfeeding supportive practices in European hospitals during the COVID-19 pandemic. J Matern-Fetal Neonatal Med. 2021;34(24).","DOI":"10.1080\/14767058.2021.1986482"},{"key":"10.3233\/NPM-210883_ref32","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41390-020-01226-3","article-title":"Favorable outcomes among neonates not separated from their symptomatic SARS-CoV-2-infected mothers","volume":"90","author":"Martenot","year":"2021","journal-title":"Pediatr Res"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/NPM-210883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:42:07Z","timestamp":1777614127000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospress&doi=10.3233\/NPM-210883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,12]]},"references-count":32,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3233\/npm-210883","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,12]]}}}