{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:30:47Z","timestamp":1777890647742,"version":"3.51.4"},"reference-count":54,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2022,12,23]]},"abstract":"<jats:p>Optimal fluid management of preterm babies with suspected or confirmed diagnosis of patent ductus arteriosus (PDA) is frequently challenging for neonatal care physician because of paucity of clinical trials. There is wide variation in practice across neonatal units, resulting in significant impact on outcomes in Extremely Low Birth Weight (ELBW) babies with hemodynamically significant PDA. A delicate balance is required in fluid management to reduce mortality and morbidity in this population. The purpose of this review is to lay out the current understanding about fluid and electrolyte management in ELBW babies with hemodynamically significant PDA and highlight areas for future research.<\/jats:p>","DOI":"10.3233\/npm-210943","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T13:10:08Z","timestamp":1652793008000},"page":"689-697","source":"Crossref","is-referenced-by-count":4,"title":["Fluid and electrolyte management in preterm infants with patent ductus arteriosus"],"prefix":"10.1177","volume":"15","author":[{"given":"R.","family":"Lalitha","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Western Ontario, Division of Neonatal-Perinatal Medicine, London, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Surak","sequence":"additional","affiliation":[{"name":"University of Alberta, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bitar","sequence":"additional","affiliation":[{"name":"University of Alberta, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Hyderi","sequence":"additional","affiliation":[{"name":"University of Alberta, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Kumaran","sequence":"additional","affiliation":[{"name":"University of Alberta, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"11","key":"10.3233\/NPM-210943_ref1","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1056\/NEJM198003133021103","article-title":"Effect of fluid administration on the development of symptomatic patent ductus arteriosus and congestive heart failure in","volume":"302","author":"Bell","year":"1980","journal-title":"N Engl J Med"},{"issue":"6","key":"10.3233\/NPM-210943_ref2","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/S0022-3476(78)80382-5","article-title":"Bronchopulmonary dysplasia: Possible relationship to pulmonary edema","volume":"92","author":"Brown","year":"1978","journal-title":"J Pediatr"},{"issue":"2","key":"10.3233\/NPM-210943_ref3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/sj.jp.7211895","article-title":"Fluid regimens in the first week of life may increase risk of patent ductus arteriosus in extremely low birth weight infants","volume":"28","author":"Stephens","year":"2008","journal-title":"J Perinatol"},{"issue":"3","key":"10.3233\/NPM-210943_ref4","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1542\/peds.91.3.552","article-title":"Association between neonatal care practices and efficacy of exogenous human surfactant: Results of a bicenter randomized trial","volume":"91","author":"Hallman","year":"1993","journal-title":"Pediatrics"},{"issue":"6","key":"10.3233\/NPM-210943_ref5","first-page":"1345","article-title":"Risk factors for chronic lung disease in the surfactant era: A North Carolina population-based study of very low birth weight infants","volume":"104","author":"Marshall","year":"1999","journal-title":"North Carolina Neonatologists Association. 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