{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:30:51Z","timestamp":1777890651443,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2023,3,28]]},"abstract":"<jats:p>BACKGROUND: Varicella vaccination of non-immune post-partum women is recommended to reduce the risk of chickenpox in mothers and their infants. Though rare, transmission of the varicella vaccine strain vOka can occur from recent vaccinees to non-immune contacts who usually develop mild chickenpox. METHODS\/RESULTS: Here we describe an infant hospitalized in the neonatal ICU with vaccine-strain varicella due to transmission from their mother who received the varicella vaccine post-partum. We describe the infection prevention and control strategies implemented to prevent further transmission. CONCLUSION: Vaccine-strain varicella transmission from mother to infant is a rare event and its occurrence in the neonatal ICU setting can be challenging. Anticipatory guidance for mothers vaccinated in the postpartum period and support of parents of an infected infant are recommended.<\/jats:p>","DOI":"10.3233\/npm-221031","type":"journal-article","created":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T11:17:32Z","timestamp":1675423052000},"page":"179-182","source":"Crossref","is-referenced-by-count":2,"title":["Varicella in the neonatal ICU due to the Varicella vaccine Oka strain"],"prefix":"10.1177","volume":"16","author":[{"given":"I.","family":"Frantzis","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Columbia University Irving Medical Center, New York City, New York, USA"},{"name":"NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Messina","sequence":"additional","affiliation":[{"name":"Department of Infection Prevention and Control, New York-Presbyterian Hospital, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Northwell Health Physician Partners, Northern Westchester Hospital, Mount Kisco, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Aschheim","sequence":"additional","affiliation":[{"name":"NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University Irving Medical Center, New York City, New York, USA"},{"name":"NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.C.","family":"Hairston","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.T.","family":"Lauren","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University Irving Medical Center, New York City, New York, USA"},{"name":"Department of Dermatology, Columbia University Irving Medical Center, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gershon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University Irving Medical Center, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Feldstein","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Columbia University Irving Medical Center, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Orange","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University Irving Medical Center, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Saiman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University Irving Medical Center, New York City, New York, USA"},{"name":"Department of Infection Prevention and Control, New York-Presbyterian Hospital, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"5","key":"10.3233\/NPM-221031_ref1","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1128\/JCM.06630-11","article-title":"Novel genetic variation identified at fixed loci in ORF62 of the Oka varicella vaccine and in a case of vaccine-associated herpes zoster","volume":"50","author":"Quinlivan","year":"2012","journal-title":"J Clin Microbiol"},{"issue":"11","key":"10.3233\/NPM-221031_ref2","doi-asserted-by":"crossref","first-page":"4781","DOI":"10.1172\/JCI71927","article-title":"A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR(-) B cells","volume":"123","author":"Boisson","year":"2013","journal-title":"J Clin Invest"},{"issue":"4","key":"10.3233\/NPM-221031_ref3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.siny.2008.11.008","article-title":"Varicella in the fetus and newborn","volume":"14","author":"Smith","year":"2009","journal-title":"Semin Fetal Neonatal Med"},{"issue":"4","key":"10.3233\/NPM-221031_ref4","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1086\/338832","article-title":"National Institute of Child Health and Human Development, Network of Maternal-Fetal Medicine Units. Risk factors and outcome of varicella-zoster virus pneumonia in pregnant women","volume":"185","author":"Harger","year":"2002","journal-title":"J Infect Dis"},{"issue":"1","key":"10.3233\/NPM-221031_ref6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1542\/peds.2007-1089","article-title":"Prevention of varicella: recommendations for use of varicella vaccines in children, including a recommendation for a routine 2-dose varicella immunization schedule","volume":"120","author":"American Academy of Pediatrics Committee on Infectious Diseases","year":"2007","journal-title":"Pediatrics"},{"issue":"3","key":"10.3233\/NPM-221031_ref7","doi-asserted-by":"crossref","first-page":"e20191305","DOI":"10.1542\/peds.2019-1305","article-title":"Transmission of Vaccine-Strain Varicella-Zoster Virus: A Systematic Review","volume":"144","author":"Marin","year":"2019","journal-title":"Pediatrics"},{"issue":"9","key":"10.3233\/NPM-221031_ref8","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/INF.0b013e31825d2a1b","article-title":"Neonatal vaccine-strain varicella-zoster virus infection 22 days after maternal postpartum vaccination","volume":"31","author":"Kluthe","year":"2012","journal-title":"Pediatr Infect Dis J"},{"issue":"10","key":"10.3233\/NPM-221031_ref9","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1093\/jpids\/piac050","article-title":"Vaccine-Strain Varicella Virus Transmitted to a Term Infant Following Maternal Postpartum Vaccination","volume":"11","author":"Saringkarisate","year":"2022","journal-title":"J Pediatric Infect Dis Soc"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/NPM-221031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:42:32Z","timestamp":1777614152000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospress&doi=10.3233\/NPM-221031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,28]]},"references-count":8,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3233\/npm-221031","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,28]]}}}