{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:07:11Z","timestamp":1781665631017,"version":"3.54.5"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2023,6,27]]},"abstract":"<jats:p>PURPOSE: Infection with COVID-19 during pregnancy has been associated with a hypercoagulable state. It is unknown if maternal COVID-19 infection results in congenital anomalies secondary to intrauterine vascular accidents. This study sought to determine if the rate of in-utero vascular complications (intestinal atresia and limb abnormalities) that may be attributable to the hypercoagulable states associated with COVID-19 and pregnancy increased after the onset of the pandemic. METHODS: Pregnancy, neonatal, and congenital defect data from a single academic medical center and the partner\u2019s children\u2019s hospital were collected and compared to the period prior to onset of the pandemic. A subanalysis including pregnant woman 18 years or greater with documented COVID-19 infection during gestation between March 2020-2021 was performed. RESULTS: Rates of intestinal atresia did not differ prior to or after the onset of the pandemic (3.78% vs 7.23%, p\u200a=\u200a0.21) nor did rates of limb deficiency disorders (4.41% vs 9.65%, p\u200a=\u200a0.09). On subanalysis, there were 194 women with COVID-19 infection included in analysis: 135 (69.6%) were positive during delivery admission and 59 (30.4%) were positive earlier in their pregnancy. There was one infant born with intestinal atresia. CONCLUSION: We report a low incidence of congenital anomalies in infants born to mothers with COVID-19 infection. It remains unclear if the impact of COVID-19 on the coagulative state augments the normal pro-thrombotic state of pregnancy; ongoing surveillance is warranted.<\/jats:p>","DOI":"10.3233\/npm-221122","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T13:00:03Z","timestamp":1682082003000},"page":"227-234","source":"Crossref","is-referenced-by-count":7,"title":["Incidence of congenital complications related to COVID-19 infection during pregnancy"],"prefix":"10.1177","volume":"16","author":[{"given":"M.L.","family":"Reppucci","sequence":"first","affiliation":[{"name":"Pediatric Surgery, Children\u2019s Hospital Colorado, Aurora, CO, USA"},{"name":"Department of Surgery, Division of Pediatric Surgery, University of Colorado School of Medicine, Aurora, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Kaizer","sequence":"additional","affiliation":[{"name":"The Center for Research in Outcomes for Children\u2019s 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