{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T07:52:15Z","timestamp":1781769135591,"version":"3.54.5"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T00:00:00Z","timestamp":1702684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2023,12,18]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>We aimed to describe our experience with gabapentin use in infants admitted to our neonatal intensive care unit (NICU), including neurodevelopmental follow-up after discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We performed a retrospective medical record review of infants prescribed gabapentin during admission to the University of Virginia NICU from 01\/01\/2015 to 04\/30\/2021. We report clinical characteristics including gabapentin indication, dosing and side-effects while in the NICU, discharge data, and assessments in outpatient developmental follow-up clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Gabapentin was prescribed to 104 infants (median gestational age 29 weeks, median postmenstrual age at initiation 41 weeks). Sixty-one percent of infants were male. The primary indication was irritability in 86%, and 67% were receiving at least one other neurosedative medication. Median maximum dose was 25\u200amg\/kg\/day (IQR 15\u201335\u200amg\/kg\/day) and 84% were discharged home on gabapentin. The majority required equipment at discharge (64% gastrostomy or nasogastric tube feeds, 54% supplemental oxygen or mechanical ventilation, and 40% both). At the first neurodevelopmental follow-up appointment, at least one area of delay was identified in 93% of infants and by 2 years corrected age 66% had a diagnosis of global developmental delay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>NICU patients treated with gabapentin often require complex post-discharge care and require close neurodevelopmental follow up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/npm-230015","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T10:59:21Z","timestamp":1703242761000},"page":"717-723","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Gabapentin use in the neonatal intensive care unit and beyond: Single center report of 104 cases"],"prefix":"10.1177","volume":"16","author":[{"given":"M.","family":"Elliott","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Fairchild","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Burnsed","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Zanelli","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Heinan","sequence":"additional","affiliation":[{"name":"Department of Neurology and Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.P.","family":"Goodkin","sequence":"additional","affiliation":[{"name":"Department of Neurology and Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Frazier","sequence":"additional","affiliation":[{"name":"Division of Developmental Pediatrics, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Letzkus","sequence":"additional","affiliation":[{"name":"Division of Developmental Pediatrics, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,12,16]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1046\/j.0003-2409.2001.02399.x"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.5505\/agri.2013.98852"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2015.09.007"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14324"},{"issue":"3","key":"ref005","first-page":"207","volume":"22","author":"Sacha GL","year":"2017","journal-title":"J Pediatr Pharmacol Ther"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2019.02.012"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.10.013"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-022-03009-5"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.5863\/1551-6776-23.1.59"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.1689"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(97)00092-3"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70016-8"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-9651(18)30569-2"},{"key":"ref014","unstructured":"RossettiLThe Rossetti infant-toddler language scale: A measure of communication and interaction. 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