{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:31:03Z","timestamp":1777890663998,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2023,6,27]]},"abstract":"<jats:p>BACKGROUND: Severe perinatal depression is a significant cause of mortality and morbidity in neonates. Vitamin D levels were observed to be low in mothers and their neonates with hypoxic ischemic encephalopathy in some studies, owing to its neuroprotective properties. OBJECTIVE: Primary objective was to compare vitamin D deficiency state in full term neonates with severe perinatal depression and healthy term controls. Secondary objectives were to determine sensitivity and specificity of serum 25(OH)D&lt;12\u200ang\/mL in predicting mortality, development of hypoxic ischemic encephalopathy, abnormal neurological examination at discharge, and developmental outcome at 12 weeks of age. MATERIAL AND METHODS: Serum 25(OH)D levels in full term neonates with severe perinatal depression and healthy controls were compared. RESULTS: Serum 25(OH)D levels in severe perinatal depression and controls (n\u200a=\u200a55 each group) were significantly different (7.50 \u00b1 3.53\u200ang\/mL vs 20.23 \u00b1 12.70\u200ang\/mL). At cut-off of\u200a&lt;\u200a12\u200ang\/mL, serum 25(OH)D could predict mortality with 100% sensitivity and 17% specificity and poor developmental outcomes with sensitivity of 100% and specificity of 50%. CONCLUSION: Vitamin D deficiency status at birth can serve as an effective screening tool and poor prognostic markers in term neonates with severe perinatal depression.<\/jats:p>","DOI":"10.3233\/npm-230020","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T10:57:22Z","timestamp":1686913042000},"page":"257-264","source":"Crossref","is-referenced-by-count":2,"title":["Serum Vitamin D status in full term neonates with severe perinatal depression"],"prefix":"10.1177","volume":"16","author":[{"given":"P.","family":"Batra","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.S.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Harit","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/NPM-230020_ref1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3233\/NPM-16152","article-title":"Hypoxic-ischemic brain injury: Planned delivery before intrapartum events","volume":"10","author":"Odd","year":"2017","journal-title":"J Neonat Perinat Med"},{"key":"10.3233\/NPM-230020_ref2","unstructured":"National Neonatology Forum. 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