{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:31:22Z","timestamp":1777890682927,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:00:00Z","timestamp":1712966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2024,5,16]]},"abstract":"\n BACKGROUND:<\/jats:title>\n Congenital syphilis is a vertical infection caused by Treponema pallidum. Despite the implementation of preventive strategies during pregnancy, its incidence is increasing, and it constitutes an important public health problem. Most patients with congenital syphilis are asymptomatic; however, a small group may develop severe disease at birth with the need of advanced resuscitation in the delivery room, acute hypoxemic respiratory failure, and hemodynamic instability. Therefore, awareness is needed.<\/jats:p>\n <\/jats:sec>\n \n METHODS AND RESULTS:<\/jats:title>\n This series describes the clinical course of two late preterm infants with congenital syphilis who developed acute hypoxemic respiratory failure, pulmonary hypertension, and circulatory collapse early after birth. Integrated hemodynamic evaluation with neonatologist-performed echocardiography (NPE) and therapeutic management is provided.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n A comprehensive hemodynamic evaluation including early and serial functional echocardiography in these patients is needed to address the underlying complex pathophysiology and to help to establish accurate treatment.<\/jats:p>\n <\/jats:sec>","DOI":"10.3233\/npm-230133","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T11:14:37Z","timestamp":1713266077000},"page":"255-260","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Severe pulmonary hypertension and circulatory failure associated with Congenital syphilis. Case report"],"prefix":"10.1177","volume":"17","author":[{"given":"M.","family":"Sanchez-Holgado","sequence":"first","affiliation":[{"name":"Department of Neonatology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.C.","family":"Bravo","sequence":"additional","affiliation":[{"name":"Department of Neonatology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Alvarez-Garcia","sequence":"additional","affiliation":[{"name":"Department of Neonatology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Lopez-Ortego","sequence":"additional","affiliation":[{"name":"Department of Neonatology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Criado Camargo","sequence":"additional","affiliation":[{"name":"Department of Neonatology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pellicer","sequence":"additional","affiliation":[{"name":"Department of Neonatology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,13]]},"reference":[{"key":"ref001","unstructured":"Centers for Disease Control and PreventionSexually transmitted disease surveillance 2020. Preliminary 2021 Data: Syphilis. https:\/\/www.cdc.gov\/std\/statistics\/2020\/preliminary2021.htm."},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2021.03.005"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2018.02.005"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.2019.v109i9.13817"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000003370"},{"issue":"4","key":"ref006","first-page":"223","volume":"63","author":"Spear ML","year":"1991","journal-title":"Del Med J"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2015.03.001"},{"key":"ref008","unstructured":"McNamaraPJ, GiesingerRE, LakshminrusimhaS. Dopamine and neonatal pulmonary hypertension-pressing need for a better pressor? J Pediatr. 2022:S0022-3476(22)00207-4."}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-230133","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/NPM-230133","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/NPM-230133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:43:34Z","timestamp":1777614214000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/NPM-230133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,13]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,5,16]]}},"alternative-id":["10.3233\/NPM-230133"],"URL":"https:\/\/doi.org\/10.3233\/npm-230133","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,13]]}}}