{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:31:30Z","timestamp":1777890690624,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NPM"],"published-print":{"date-parts":[[2024,10,15]]},"abstract":"<jats:p>BACKGROUND: There is no objective criteria to wean CPAP in preterm neonates. We aimed to assess the accuracy of \u2018saturation trends\u2019 to predict successful CPAP discontinuation. METHODS: We included very preterm neonates who required CPAP. Index tests were \u2018saturation trends\u2019. Outcome was successful CPAP discontinuation, defined as baby stable in room air for 72\u200ah. RESULTS: We had 120 neonates with mean\u00b1SD gestation 28.6\u00b11.8 weeks. 96 (80%) neonates had successful discontinuation and 24 (20%) failed. Neonates with successful discontinuation had significantly greater \u2018saturation trends\u2019 during 24\u200ah before discontinuing CPAP compared to those who failed [64.3 (48.1\u201383.7) vs. 47.3 (23.0\u201365.0), p\u200a=\u200a0.001]. Saturations\u200a&gt;\u200a95% while on CPAP with 21% FiO2 for\u200a&gt;\u200a60% time had 63% sensitivity and 70% specificity to predict successful CPAP discontinuation. CONCLUSION: \u2018Saturation trends\u2019 is a readily available objective parameter that can be used to guide weaning CPAP in preterm neonates.<\/jats:p>","DOI":"10.3233\/npm-230192","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T10:36:08Z","timestamp":1726828568000},"page":"647-651","source":"Crossref","is-referenced-by-count":0,"title":["Utility of saturation trends to predict successful weaning of nasal CPAP in very preterm neonates \u2013 A prospective study"],"prefix":"10.1177","volume":"17","author":[{"given":"T.","family":"Abiramalatha","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Unit; Kovai Medical Center and Hospital (KMCH), Coimbatore, India"},{"name":"KMCH Research Foundation, Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Govindaraju","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit; Kovai Medical Center and Hospital (KMCH), Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Rajaiah","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit; Kovai Medical Center and Hospital (KMCH), Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Chandrasekar","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit; Kovai Medical Center and Hospital (KMCH), Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit; Kovai Medical Center and Hospital (KMCH), Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit; Kovai Medical Center and Hospital (KMCH), Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"6","key":"10.3233\/NPM-230192_ref1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1177\/000992287000900607","article-title":"Respiratory distress syndrome of the newborn infant","volume":"9","author":"Downes","year":"1970","journal-title":"Clin Pediatr"},{"key":"10.3233\/NPM-230192_ref2","first-page":"1","article-title":"A controlled clinical trial of effects of water mist on obstructive respiratory signs, death rate and necropsy findings among premature infants","volume":"17","author":"Silverman","year":"1956","journal-title":"Pediatrics"},{"issue":"2","key":"10.3233\/NPM-230192_ref3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1038\/jp.2013.157","article-title":"Transcribed oxygen saturation vs oximeter recordings in very low birth weight infants","volume":"34","author":"Ruiz","year":"2014","journal-title":"J Perinatol"},{"issue":"4","key":"10.3233\/NPM-230192_ref4","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/s41390-020-0772-2","article-title":"Oxygen saturation histograms predict nasal continuous positive airway pressure-weaning success in preterm infants","volume":"88","author":"Gentle","year":"2020","journal-title":"Pediatr Res"},{"issue":"4","key":"10.3233\/NPM-230192_ref5","doi-asserted-by":"crossref","first-page":"416","DOI":"10.4187\/respcare.04102","article-title":"The objective use of pulse oximetry to predict respiratory support transition in preterm infants: An observational pilot study","volume":"61","author":"Mascoll-Robertson","year":"2016","journal-title":"Respir Care"},{"issue":"2","key":"10.3233\/NPM-230192_ref6","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/s41390-019-0527-0","article-title":"Continuous vital sign analysis for predicting and preventing neonatal diseases in the twenty-first century: Big data to the forefront","volume":"87","author":"Kumar","year":"2020","journal-title":"Pediatr Res"},{"issue":"4","key":"10.3233\/NPM-230192_ref7","doi-asserted-by":"crossref","first-page":"F329","DOI":"10.1136\/archdischild-2015-309210","article-title":"Heart rate characteristic index monitoring for bloodstream infection in an NICU: A 3-year experience","volume":"101","author":"Coggins","year":"2016","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"4","key":"10.3233\/NPM-230192_ref8","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1055\/s-0041-1728829","article-title":"Sepsis and mortality prediction in very low birth weight infants: Analysis of HeRO and nSOFA","volume":"40","author":"Zeigler","year":"2023","journal-title":"Am J Perinatol"},{"issue":"6","key":"10.3233\/NPM-230192_ref9","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1055\/s-0040-1718877","article-title":"Longitudinal analysis of continuous pulse oximetry as prognostic factor in neonatal respiratory distress","volume":"39","author":"Sol\u00eds-Garc\u00eda","year":"2022","journal-title":"Am J Perinatol"},{"issue":"13","key":"10.3233\/NPM-230192_ref10","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1055\/s-0038-1654712","article-title":"Early pulse oximetry data improves prediction of death and adverse outcomes in a two-center cohort of very low birth weight infants","volume":"35","author":"Sullivan","year":"2018","journal-title":"Am J Perinatol"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/NPM-230192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:43:47Z","timestamp":1777614227000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospress&doi=10.3233\/NPM-230192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,15]]},"references-count":10,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3233\/npm-230192","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,15]]}}}