{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:35:03Z","timestamp":1777890903817,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T00:00:00Z","timestamp":1455235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["NeuroRehabilitation: An International, Interdisciplinary Journal"],"published-print":{"date-parts":[[2016,2,18]]},"abstract":"\n BACKGROUND:<\/jats:title>\n \n An equation for predicting the gross oxygen uptake (gross-VO\n 2<\/jats:sub>\n ) during walking for persons with multiple sclerosis (MS) has been developed. Predictors included walking speed and total score from the 12-Item Multiple Sclerosis Walking Scale (MSWS-12).\n <\/jats:p>\n <\/jats:sec>\n \n OBJECTIVE:<\/jats:title>\n This study examined the validity of this prediction equation in another sample of persons with MS.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n \n Participants were 18 persons with MS with limited mobility problems (42 \u00b1 13 years; 14 women). Participants completed the MSWS-12. Gross-VO\n 2<\/jats:sub>\n was measured with open-circuit spirometry during treadmill walking at 2.0, 3.0, and 4.0 mph (0.89, 1.34, and 1.79 m\u00b7s\n \u20131<\/jats:sup>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n REULTS:<\/jats:title>\n \n Absolute percent error was small: 8.3 \u00b1 6.1% , 8.0 \u00b1 5.6% , and 12.2 \u00b1 9.0% at 2.0, 3.0, and 4.0 mph, respectively. Actual gross-VO\n 2<\/jats:sub>\n did not differ significantly from predicted gross-VO\n 2<\/jats:sub>\n at 2.0 and 3.0 mph, but was significantly higher than predicted gross-VO\n 2<\/jats:sub>\n at 4.0 mph ( p\u200a< \u200a0.001). Bland-Altman plots indicated nearly zero mean difference between actual and predicted gross-VO\n 2<\/jats:sub>\n with modest 95% confidence intervals at 2.0 and 3.0 mph, but there was some underestimation at 4.0 mph.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n \n Speed and MSWS-12 score provide valid prediction of gross-VO\n 2<\/jats:sub>\n during treadmill walking at slow and moderate speeds in ambulatory persons with MS. However, there is a possibility of small underestimation for walking at 4.0 mph.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3233\/nre-161310","type":"journal-article","created":{"date-parts":[[2016,3,22]],"date-time":"2016-03-22T11:26:08Z","timestamp":1458645968000},"page":"191-197","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Cross-validation of oxygen uptake prediction during walking in ambulatory persons with multiple sclerosis"],"prefix":"10.1177","volume":"38","author":[{"given":"Stamatis","family":"Agiovlasitis","sequence":"first","affiliation":[{"name":"Department of Kinesiology, Mississippi State University, Mississippi State, MS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert W.","family":"Motl","sequence":"additional","affiliation":[{"name":"Department of Kinesiology & Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,2,12]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0570"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-010-1812-0"},{"key":"ref003","author":"Agiovlasitis S.","journal-title":"Journal of Rehabilitation Research and Development."},{"key":"ref004","volume-title":"ACSM\u2019s Guidelines for Exercise Testing and Prescription","author":"American College of Sports Medicine","year":"2014","edition":"9"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1177\/1352458506073780"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1177\/096228029900800204"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1177\/1352458507079445"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.60.1.31"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.2.251"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1177\/135245859900500508"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199310000-00012"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1997.83.6.1998"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.2165\/11591150-000000000-00000"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2013.04.020"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1177\/1352458513483890"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-13-37"},{"key":"ref017","volume-title":"Exercise physiology: Energy, nutrition, and human performance","author":"McArdle W. 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