{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:35:45Z","timestamp":1777890945739,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T00:00:00Z","timestamp":1486684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["NeuroRehabilitation: An International, Interdisciplinary Journal"],"published-print":{"date-parts":[[2017,5,4]]},"abstract":"<jats:p>OBJECTIVE: Appropriate afferent feedback delivery during the execution of motor tasks is important for rehabilitation after incomplete spinal cord injury (iSCI). However, during leg-cycling therapy, the plantar afferent feedback is minimal. We hypothesize that the augmentation of sensory input by combining cycling with a locomotor-like stimulation of plantar cutaneous innervations (ES-cycling), might help to restore proper spinal processing of sensorimotor function.<\/jats:p>\n                  <jats:p>METHODS: Thirteen non-injured subjects and 10 subjects with iSCI performed 10 minutes of cycling and, on another session, of ES-cycling. To assess spinal processing of sensorimotor function, soleus H-reflex response was tested following a conditioning plantar electrical stimulation applied at 25\u2013100\u200ams inter-stimulus intervals (ISI\u2019s), measured before and after the execution of the tasks.<\/jats:p>\n                  <jats:p>RESULTS: Before tasks execution, the conditioned H-reflex response was modulated in non-injured subjects, and absent in subjects with iSCI; after cycling, modulation profiles were unchanged. However, after ES-cycling a significant increase in H-reflex excitability was observed in the non-injured group at 100\u200ams ISI ( p\u200a&lt;\u200a0.05), and in the iSCI group between 50\u201375\u200ams ISI ( p\u200a&lt;\u200a0.001).<\/jats:p>\n                  <jats:p>CONCLUSION: The loss of reflex modulation in subjects with iSCI suggests reduced spinal processing of sensorimotor function. Reflex modulation recovery after ES-cycling may indicate the partial reactivation of these mechanisms.<\/jats:p>","DOI":"10.3233\/nre-161430","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T09:48:35Z","timestamp":1486720115000},"page":"429-437","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Afferent electrical stimulation during cycling improves spinal processing of sensorimotor function after incomplete spinal cord injury"],"prefix":"10.1177","volume":"40","author":[{"given":"Stefano","family":"Piazza","sequence":"first","affiliation":[{"name":"Neural Rehabilitation Group, Cajal Institute, Consejo Superior de Investigaciones Cient\u00edficas, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Serrano-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Sensorimotor Function Group, Hospital Nacional de Parapl\u00e9jicos, Toledo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"G\u00f3mez-Soriano","sequence":"additional","affiliation":[{"name":"Sensorimotor Function Group, Hospital Nacional de Parapl\u00e9jicos, Toledo, Spain"},{"name":"Toledo Physiotherapy Research Group, Nursing and Physiotherapy School,  Castilla La Mancha University, Toledo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Torricelli","sequence":"additional","affiliation":[{"name":"Neural Rehabilitation Group, Cajal Institute, Consejo Superior de Investigaciones Cient\u00edficas, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Segura-Fragosa","sequence":"additional","affiliation":[{"name":"Health Sciences Institute, Consejer\u00eda de Sanidad, Talavera de la Reina, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Pons","sequence":"additional","affiliation":[{"name":"Neural Rehabilitation Group, Cajal Institute, Consejo Superior de Investigaciones Cient\u00edficas, Madrid, Spain"},{"name":"Tecnol\u00f3gico de Monterrey, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Taylor","sequence":"additional","affiliation":[{"name":"Sensorimotor Function Group, Hospital Nacional de Parapl\u00e9jicos, Toledo, Spain"},{"name":"Stoke Mandeville Spinal Research, National Spinal Injuries Centre, Aylesbury, UK"},{"name":"Harris Manchester College, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,2,10]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.01.033"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/67.2.206"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(96)00061-5"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410370506"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp124"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101223"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000202600.72018.39"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1994.72.5.2090"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3034963"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1177\/1545968311420844"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1007\/BF00227268"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1016\/S1050-6411(02)00034-2"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2007.06.014"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101917"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00880.2009"},{"issue":"2","key":"ref016","first-page":"206","volume":"67","author":"Knikou M.","year":"2012","journal-title":"Neural Plasticity"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1002\/mus.22265"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3100432"},{"key":"ref019","unstructured":"Medical Research Council of the UK. 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