{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:46:37Z","timestamp":1791852397325,"version":"4.3.4"},"reference-count":55,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NRE"],"published-print":{"date-parts":[[2019,2,20]]},"DOI":"10.3233\/nre-182553","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T14:48:21Z","timestamp":1549982901000},"page":"111-129","source":"Crossref","is-referenced-by-count":8,"title":["The association between temporal measures of swallowing with penetration and aspiration in patients with dysphagia: A meta-analysis"],"prefix":"10.1177","volume":"44","author":[{"given":"Ana Maria","family":"Furkim","sequence":"first","affiliation":[{"name":"Department of Speech-Language Pathology, University of Toronto, Canada"},{"name":"Department of Speech-Language Pathology and Hearing Sciences, Federal University of Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta Gon\u00e7alves","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Speech-Language Pathology and Hearing Sciences, S\u00e3o Paulo State University-UNESP at Mar\u00edlia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Vanin","sequence":"additional","affiliation":[{"name":"Swallowing Lab, University of Toronto, University Health Network, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary","family":"Martino","sequence":"additional","affiliation":[{"name":"Swallowing Lab, University of Toronto, University Health Network, Canada"},{"name":"Department of Speech-Language Pathology, Rehabilitation Sciences Institute, Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Canada"},{"name":"Affiliate Scientist, Krembil Research Institute, University Health Network, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"issue":"7521","key":"10.3233\/NRE-182553_ref1","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1136\/bmj.331.7521.903","article-title":"Standard deviations and standard errors","volume":"331","author":"Altman","year":"2005","journal-title":"BMJ"},{"issue":"6","key":"10.3233\/NRE-182553_ref2","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00455-015-9653-y","article-title":"Videofluoroscopic predictors of penetration-aspiration in parkinson's disease p atients","volume":"30","author":"Argolo","year":"2015","journal-title":"Dysphagia"},{"issue":"1","key":"10.3233\/NRE-182553_ref3","doi-asserted-by":"crossref","first-page":"42","DOI":"10.4103\/0028-3886.60395","article-title":"Quantitative videofluoroscopic analysis of penetrationaspiration in post-stroke patients","volume":"58","author":"Bingjie","year":"2010","journal-title":"Neurol India"},{"issue":"5","key":"10.3233\/NRE-182553_ref4","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1080\/00016489850183269","article-title":"Thermal oral-pharyngeal stimulation and elicitation of swallowing","volume":"118","author":"Bove","year":"1998","journal-title":"Acta Otolaryngol"},{"issue":"62","key":"10.3233\/NRE-182553_ref5","first-page":"1471","article-title":"Swallowing transit times and valleculae residue in stable chronic obstructive pulmonary disease","volume":"14","author":"Chaves","year":"2014","journal-title":"BMC Pulmonary Medicine"},{"issue":"9","key":"10.3233\/NRE-182553_ref6","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1111\/j.1365-2036.2006.03118.x","article-title":"The effect of bolus viscosity on swallowing function in neurogenic dysphagia","volume":"24","author":"Clave","year":"2006","journal-title":"Aliment Phar-macolTher"},{"issue":"1","key":"10.3233\/NRE-182553_ref7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF02407397","article-title":"Timing of videofluoro-scopic, manometric events, and bolus transit during the oral and pharyngeal phases of swallowing","volume":"4","author":"Cook","year":"1989","journal-title":"Dysphagia"},{"issue":"6","key":"10.3233\/NRE-182553_ref8","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/00004424-198411000-00009","article-title":"Timing in the normal pharyngeal swallow: Prospective selection and evaluation of 16 normal asymptomatic patients","volume":"19","author":"Curtis","year":"1984","journal-title":"Investigative Radiology"},{"issue":"1","key":"10.3233\/NRE-182553_ref9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1159\/000339888","article-title":"Taste and temperature in swallowing transit time after stroke","volume":"2","author":"Cola","year":"2012","journal-title":"Cerebrovasc Dis Extra"},{"issue":"2","key":"10.3233\/NRE-182553_ref10","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1044\/1058-0360(2007\/018)","article-title":"Effects of verbal cue on bolus flow during swallowing","volume":"16","author":"Daniels","year":"2007","journal-title":"Am J Speech Lang Pathol"},{"issue":"3","key":"10.3233\/NRE-182553_ref11","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1007\/BF00341259","article-title":"Manofluorographic analysis of swallowing in the elderly","volume":"9","author":"Dejaeger","year":"1994","journal-title":"Dysphagia"},{"issue":"5","key":"10.3233\/NRE-182553_ref12","doi-asserted-by":"crossref","first-page":"965","DOI":"10.2214\/ajr.154.5.2108570","article-title":"Radiologic assessment of abnormal oral and pharyngeal phases of swallowing. AJR","volume":"154","author":"Dodds","year":"1990","journal-title":"American Journal of Roentgenology"},{"issue":"6","key":"10.3233\/NRE-182553_ref13","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.2214\/ajr.150.6.1307","article-title":"Influence of bolus volume on swallow-induced hyoid movement in normal subjects","volume":"150","author":"Dodds","year":"1988","journal-title":"AJR American Journal of Roentgenology"},{"issue":"5","key":"10.3233\/NRE-182553_ref14","doi-asserted-by":"crossref","first-page":"953","DOI":"10.2214\/ajr.154.5.2108569","article-title":"Physiology and radiology of the normal oral and pharyngeal phases of swallowing","volume":"154","author":"Dodds","year":"1990","journal-title":"AJR American Journal ofRoentgenology"},{"key":"10.3233\/NRE-182553_ref15","first-page":"393","volume-title":"AJR.","author":"Eisenhuber","year":"2002"},{"issue":"5","key":"10.3233\/NRE-182553_ref16","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/0003489415617774","article-title":"Quantitative measures of swallowing deficits in patients with parkinson's disease","volume":"125","author":"Ellerston","year":"2016","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"8842","key":"10.3233\/NRE-182553_ref17","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/0140-6736(93)93023-T","article-title":"Capsaicin and swallowing reflex","volume":"341","author":"Ebihara","year":"1993","journal-title":"Lancet"},{"issue":"2","key":"10.3233\/NRE-182553_ref18","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1590\/S2317-17822013000200012","article-title":"Sour taste and cold temperature in the oral phase of swallowing in patients after stroke","volume":"25","author":"Gatto","year":"2013","journal-title":"CoDAS"},{"key":"10.3233\/NRE-182553_ref19","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.physbeh.2017.03.018","article-title":"Examination of swallowing maneuver training and transfer of practiced behaviors to laryngeal vestibule kinematics in functional swallowing of healthy adults","volume":"174","author":"Guedes","year":"2017","journal-title":"Physiology & Behavior"},{"issue":"7","key":"10.3233\/NRE-182553_ref20","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1044\/2017_JSLHR-S-16-0117","article-title":"Identification of swallowing tasks from a modified barium swallow study that optimize the detection of physiological impairment","volume":"60","author":"Hazelwood","year":"2017","journal-title":"J Speech Lang Hear Res"},{"issue":"5","key":"10.3233\/NRE-182553_ref21","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1053\/apmr.2001.21939","article-title":"Quantifying swallowing function after stroke: A functional dysphagia scale based on videofluoroscopic studies","volume":"82","author":"Han","year":"2001","journal-title":"Archives of Physical Medicine & Rehabilitation"},{"key":"10.3233\/NRE-182553_ref22","unstructured":"Higgins, J.P.T. , & Green, S.E. (2011). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]: The cochrane collaboration. Available from http:\/\/www.cochrane-handbook.org\/."},{"issue":"2","key":"10.3233\/NRE-182553_ref23","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s004550010004","article-title":"Timing of events in normal swallowing: a videofluoroscopic study","volume":"15","author":"Kendall","year":"2000","journal-title":"Dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref24","first-page":"71","article-title":"Common medical conditions in the elderly: impact on pharyngeal bolus transit","volume":"19","author":"Kendall","year":"2004","journal-title":"Dysphagia (0179051X)"},{"issue":"5","key":"10.3233\/NRE-182553_ref25","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1053\/gast.1997.v113.pm9352847","article-title":"Impaired deglutitive airway protection: a videofluoroscopic analysis of severity and mechanism","volume":"113","author":"Kharilas","year":"1997","journal-title":"Gastroenterology"},{"issue":"3","key":"10.3233\/NRE-182553_ref26","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s00455-007-9135-y","article-title":"Maximum hyoid displacement in normal swallowing","volume":"23","author":"Kim","year":"2008","journal-title":"Dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref27","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1055\/s-0029-1186278","article-title":"Kinematic analysis of hyolaryngeal complex movement in patients with dysphagia development after pneumonectomy","volume":"58","author":"Kim","year":"2010","journal-title":"Thoracic and Cardiovascular Surgeon"},{"issue":"4","key":"10.3233\/NRE-182553_ref28","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s00455-007-9085-4","article-title":"Stage transition duration in patients poststroke","volume":"22","author":"Kim","year":"2007","journal-title":"Dysphagia"},{"issue":"1","key":"10.3233\/NRE-182553_ref29","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.apmr.2012.07.016","article-title":"Changes of timing variables in swallowing of boluses with different viscosities in patients with dysphagia","volume":"94","author":"Lee","year":"2013","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"issue":"11","key":"10.3233\/NRE-182553_ref30","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1016\/j.apmr.2012.07.010","article-title":"Prolonged swallowing time in dysphagic Parkinsonism patients with aspiration pneumonia","volume":"93","author":"Lin","year":"2012","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"10.3233\/NRE-182553_ref31","doi-asserted-by":"crossref","first-page":"277","DOI":"10.2214\/ajr.153.2.277","article-title":"Interactive computer program for biomechanical analysis of videoradiographic studies of swallowing","volume":"153","author":"Logemann","year":"1989","journal-title":"AJR American Journal of Roentgenology"},{"key":"10.3233\/NRE-182553_ref32","volume-title":"A Manual for Videofluoroscopic Evaluation of Swallowing.","author":"Logemann","year":"1986"},{"issue":"4","key":"10.3233\/NRE-182553_ref33","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s00455-008-9185-9","article-title":"MBS measurement tool for swallow impairment-MBSImp: establishing a standard","volume":"23","author":"Martin-Harris","year":"2008","journal-title":"Dysphagia"},{"issue":"12","key":"10.3233\/NRE-182553_ref34","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1161\/01.STR.0000190056.76543.eb","article-title":"Dysphagia after stroke: Incidence, diagnosis, and pulmonary complications","volume":"36","author":"Martino","year":"2005","journal-title":"Stroke"},{"key":"10.3233\/NRE-182553_ref35","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1007\/s00455-013-9459-8","article-title":"The relationship between residue and aspiration on the subsequent swallow: an application of the normalized residue ratio scale","volume":"28","author":"Molfenter","year":"2013","journal-title":"dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref36","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s00455-012-9397-x","article-title":"Temporal variability in the deglutition literature","volume":"27","author":"Molfenter","year":"2012","journal-title":"Dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref37","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00455-013-9506-5","article-title":"Kinematic and temporal factors associated with penetration-aspiration in swallowing liquids","volume":"29","author":"Molfenter","year":"2014","journal-title":"Dysphagia"},{"issue":"5","key":"10.3233\/NRE-182553_ref38","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1152\/jn.00130.2016","article-title":"Sour taste increases swallowing and prolongs hemodynamic responses in the cortical swallowing network","volume":"116","author":"Mulheren","year":"2016","journal-title":"J Neurophysiol"},{"issue":"3","key":"10.3233\/NRE-182553_ref39","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1007\/s00455-013-9456-y","article-title":"Timing differences between cued and noncued swallows in healthy young adults","volume":"28","author":"Nagy","year":"2013","journal-title":"Dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref40","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/BF00417905","article-title":"Quantitative assessment of oral and pharyngeal function in Parkinson's disease","volume":"11","author":"Nilsson","year":"1996","journal-title":"Dysphagia"},{"issue":"3","key":"10.3233\/NRE-182553_ref41","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/s12603-016-0754-6","article-title":"Pharyngeal residue and aspiration and the relationship with clinical\/nutritional status of patients with oropharyngeal dysphagia submitted to videofluoroscopy","volume":"21","author":"Oliveira","year":"2017","journal-title":"J Nutr Health Aging"},{"issue":"7","key":"10.3233\/NRE-182553_ref42","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.jamda.2017.02.015","article-title":"Diagnosis and management of oropharyngeal dysphagia among older persons, state of the art","volume":"18","author":"Ortega","year":"2017","journal-title":"J Am Med Dir Assoc"},{"issue":"3","key":"10.3233\/NRE-182553_ref43","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00455-009-9237-9","article-title":"Initiation and duration of laryngeal closure during the pharyngeal swallow in post-stroke patients","volume":"25","author":"Park","year":"2010","journal-title":"Dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref44","doi-asserted-by":"crossref","first-page":"218","DOI":"10.5535\/arm.2015.39.2.218","article-title":"Effect of chronic obstructive pulmonary disease on swallowing function in stroke patients","volume":"39","author":"Park","year":"2015","journal-title":"Ann Rehabil Med"},{"issue":"2","key":"10.3233\/NRE-182553_ref45","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1136\/jnnp.2006.101857","article-title":"Deglutitive laryngeal closure in stroke patients","volume":"78","author":"Power","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"10.3233\/NRE-182553_ref46","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s00455-008-9198-4","article-title":"Predicting aspiration after hemispheric stroke from timing measures of oropharyngeal bolus flow and laryngeal closure","volume":"24","author":"Power","year":"2009","journal-title":"Dysphagia"},{"issue":"2","key":"10.3233\/NRE-182553_ref47","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1044\/jshr.3702.314","article-title":"Oropharyngeal swallow efficiency as a representative measure of swallowing function","volume":"37","author":"Rademaker","year":"1994","journal-title":"Journal of Speech & Hearing Research"},{"issue":"9","key":"10.3233\/NRE-182553_ref48","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1136\/gutjnl-2011-300753","article-title":"Natural capsaicinoids improve swallow response in older patients with oropharyngeal dysphagia","volume":"62","author":"Rofes","year":"2013","journal-title":"Gut"},{"key":"10.3233\/NRE-182553_ref49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00417897","article-title":"A Penetration-Aspiration Scale","volume":"11","author":"Rosenbek","year":"1996","journal-title":"Dysphagia"},{"issue":"3","key":"10.3233\/NRE-182553_ref50","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1093\/ageing\/afs006","article-title":"Oropharyngeal dysphagia as a risk factor for malnutrition and lower respiratory tract infection in independently living older persons: a population-based prospective study","volume":"41","author":"Serra-Prat","year":"2012","journal-title":"Age Ageing"},{"issue":"4","key":"10.3233\/NRE-182553_ref51","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s00455-015-9620-7","article-title":"Temporal and physiologic measurements of deglutition in the upright and supine position with videofluoroscopy (VFS) in healthy subjects","volume":"30","author":"Sul","year":"2015","journal-title":"Dysphagia"},{"key":"10.3233\/NRE-182553_ref52","first-page":"295","volume":"29,","author":"Steele","year":"2014","journal-title":"Physiological factors related to aspiration: A systematic Review"},{"issue":"4","key":"10.3233\/NRE-182553_ref53","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1007\/s00455-015-9618-1","article-title":"The effect of radiation dose on swallowing: evaluation of aspiration and kinematics","volume":"30","author":"Starmer","year":"2015","journal-title":"Dysphagia"},{"issue":"1","key":"10.3233\/NRE-182553_ref54","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s00455-007-9090-7","article-title":"Effects of bolus consistency on timing and safety of swallow in patients with Parkinson's disease","volume":"23","author":"Troche","year":"2008","journal-title":"Dysphagia"},{"key":"10.3233\/NRE-182553_ref55","doi-asserted-by":"crossref","first-page":"e13111","DOI":"10.1111\/nmo.13111","article-title":"Videofluoroscopic assessment of the pathophysiology of chronic poststroke oropharyngeal dysphagia","volume":"00","author":"Vilardell","year":"2017","journal-title":"Neurogastroenterol Motil"}],"container-title":["NeuroRehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/NRE-182553","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:52:03Z","timestamp":1777614723000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/NRE-182553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,20]]},"references-count":55,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3233\/nre-182553","relation":{},"ISSN":["1053-8135","1878-6448"],"issn-type":[{"value":"1053-8135","type":"print"},{"value":"1878-6448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,20]]}}}