{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T04:57:26Z","timestamp":1781931446377,"version":"3.54.5"},"reference-count":43,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NRE"],"published-print":{"date-parts":[[2021,8,14]]},"abstract":"<jats:p>BACKGROUND: Nearly half of persons with Parkinson disease (PD) report fatigue as a factor in their fall history. However, it is unknown whether these self-reported falls are caused by a sensation of fatigue or performance fatigue. OBJECTIVE: We sought to investigate the influences of performance fatigue and age on postural control in persons with PD. METHODS: Individuals with PD (n\u200a=\u200a14) underwent postural control assessments before (T0) and immediately after (T1) fatiguing exercise. Biomechanical data were gathered on participants completing a treadmill-induced, posterior-directed fall. Performance fatigue was produced using lower extremity resistance exercise on an isokinetic ergometer. Repeated measures ANCOVAs were used with age as a covariate to determine the effects of performance fatigue on biomechanical variables. RESULTS: After adjustment for age, there was a statistically significant difference in peak center of pressure (COP) latency during the support phase of recovery. Pairwise comparisons demonstrated a decrease in peak ankle displacement from T0 to T1. Age was also found to be significantly related to reaction time and peak knee displacement while participants were fatigued. CONCLUSIONS: The decreased peak COP latency, along with decreased ankle angular displacement, suggest that persons with PD adopt a stiffening strategy in response to backward directed falls. Postural stiffening is not uncommon in persons with PD and could be a risk factor for falls. Older individuals with PD demonstrate slower mobility scores and decreased reaction times in the setting of fatigue, suggesting a combined effect of the aging and fatigue processes.<\/jats:p>","DOI":"10.3233\/nre-210040","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T05:23:07Z","timestamp":1624684987000},"page":"151-159","source":"Crossref","is-referenced-by-count":3,"title":["\u201cGoing Backward\u201d: Effects of age and fatigue on posterior-directed falls in Parkinson disease"],"prefix":"10.1177","volume":"49","author":[{"given":"Evan V.","family":"Papa","sequence":"first","affiliation":[{"name":"School of Rehabilitation and Communication Sciences, Idaho State University, Meridian, ID, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita M.","family":"Patterson","sequence":"additional","affiliation":[{"name":"University of North Texas Health Science Center, Fort Worth, TX, 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