{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T16:56:24Z","timestamp":1783702584811,"version":"3.55.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NRE"],"published-print":{"date-parts":[[2021,12,24]]},"abstract":"<jats:p>BACKGROUND: Early muscle changes are believed to occur in patients with stroke. However, there are insufficient data on the changes in muscle mass and architecture of these patients. OBJECTIVES: This study investigates differences in ultrasound-derived muscle architecture parameters of the hemiplegic upper and lower limbs in patients with subacute stroke. METHODS: This is a prospective observational study, which recruited 40 adult patients who had experienced a first ever unilateral stroke (ischemic or hemorrhagic), with a duration of\u200a&lt;\u200a1 month post stroke. The brachialis, vastus lateralis and medial gastrocnemius on both the hemiplegic and normal side were evaluated via ultrasound. We recorded clinical variables including Motricity Index, Modified Ashworth Scale (MAS) and Functional Independence Measure (FIM)-walk. RESULTS: We found reduced mean muscle thickness (p\u200a&lt;\u200a0.001) and increased echo intensity (p\u200a&lt;\u200a0.001) in the brachialis muscle, increased echo intensity (p\u200a=\u200a0.002) in the vastus lateralis muscle, and reduced muscle thickness (p\u200a&lt;\u200a0.001) with increased echo intensity (p\u200a&lt;\u200a0.001) in the medial gastrocnemius muscle compared to the normal side. There were no significant correlations between ultrasound findings and Motricity Index. CONCLUSIONS: We report changes in ultrasound-derived muscle architecture in the hemiplegic limbs of patients with subacute stroke, with consistent findings of decreased muscle mass and increased echo intensity.<\/jats:p>","DOI":"10.3233\/nre-210257","type":"journal-article","created":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T12:28:38Z","timestamp":1637065718000},"page":"565-572","source":"Crossref","is-referenced-by-count":21,"title":["Changes in muscle architecture on ultrasound in patients early after stroke"],"prefix":"10.1177","volume":"49","author":[{"given":"Jong Moon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew Rong Jie","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deshan Kumar","family":"Rajeswaran","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuen-Loong","family":"Tham","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen Li","family":"Lui","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keng He","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, 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