{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:38:14Z","timestamp":1790055494606,"version":"4.0.1"},"reference-count":61,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NRE"],"published-print":{"date-parts":[[2022,8,16]]},"abstract":"<jats:p>BACKGROUND: Traumatic brain injury (TBI) often results in chronic impairments to cognitive function, and these may be related to disrupted functional connectivity (FC) of the brain at rest. OBJECTIVE: To investigate changes in default mode network (DMN) FC in adults with chronic TBI following 40 hours of auditory processing speed training. METHODS: Eleven adults with chronic TBI underwent 40-hours of auditory processing speed training over 13-weeks and seven adults with chronic TBI were assigned to a non-intervention control group. For all participants, resting-state FC and cognitive and self-reported function were measured at baseline and at a follow-up visit 13-weeks later. RESULTS: No significant group differences in cognitive function or resting-state FC were observed at baseline. Following training, the intervention group demonstrated objective and subjective improvements on cognitive measures with moderate-to-large effect sizes. Repeated measures ANCOVAs revealed significant (p\u200a&lt;\u200a0.001) group\u00d7time interactions, suggesting training-related changes in DMN FC, and semipartial correlations demonstrated that these were associated with changes in cognitive functioning. CONCLUSIONS: Changes in the FC between the DMN and other resting-state networks involved in the maintenance and manipulation of internal information, attention, and sensorimotor functioning may be facilitated through consistent participation in plasticity-based auditory processing speed training in adults with chronic TBI.<\/jats:p>","DOI":"10.3233\/nre-210264","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T11:28:39Z","timestamp":1649158119000},"page":"133-150","source":"Crossref","is-referenced-by-count":8,"title":["The effects of plasticity-based cognitive rehabilitation on resting-state functional connectivity in chronic traumatic brain injury: A pilot study"],"prefix":"10.1177","volume":"51","author":[{"given":"Hannah M.","family":"Lindsey","sequence":"first","affiliation":[{"name":"Traumatic Brain Injury and Concussion Center, Department of Neurology, University of Utah, Salt Lake City, UT, USA"},{"name":"Department of Psychology, Brigham Young University, Provo, UT, USA"},{"name":"Department of Psychology, New York University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Lazar","sequence":"additional","affiliation":[{"name":"Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Mercuri","sequence":"additional","affiliation":[{"name":"Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA"},{"name":"Department of Psychology, New York University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph F.","family":"Rath","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Rusk Rehabilitation at NYU Langone Health, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Bushnik","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Rusk Rehabilitation at NYU Langone Health, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Flanagan","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Rusk Rehabilitation at NYU Langone Health, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald T.","family":"Voelbel","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Rusk Rehabilitation at NYU Langone Health, New York, NY, USA"},{"name":"Department of Occupational Therapy and Center of Health and Rehabilitation Research, New York University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/NRE-210264_ref1","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.neuropsychologia.2014.07.034","article-title":"Partial maintenance of auditory-based cognitive training benefits in older adults","volume":"62","author":"Anderson,","year":"2014","journal-title":"Neuropsychologia"},{"issue":"5","key":"10.3233\/NRE-210264_ref2","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.neuron.2007.10.038","article-title":"Disruption of large-scale brain systems in advanced aging","volume":"56","author":"Andrews-Hanna,","year":"2007","journal-title":"Neuron"},{"issue":"2","key":"10.3233\/NRE-210264_ref6","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s11682-011-9145-0","article-title":"Neuropathology of mild traumatic brain injury: Relationship to neuroimaging findings","volume":"6","author":"Bigler,","year":"2012","journal-title":"Brain Imaging and Behavior"},{"issue":"1","key":"10.3233\/NRE-210264_ref7","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00415-014-7528-z","article-title":"Computer-aided cognitive rehabilitation improves cognitive performances and induces brain functional connectivity changes in relapsing remitting multiple sclerosis patients: an exploratory study","volume":"262","author":"Bonavita,","year":"2015","journal-title":"Journal of Neurology"},{"key":"10.3233\/NRE-210264_ref8","unstructured":"Brodmann, K. 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