{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:19:52Z","timestamp":1787242792573,"version":"build-2736575974"},"reference-count":23,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NRE"],"published-print":{"date-parts":[[2023,9,25]]},"abstract":"<jats:p>BACKGROUND: Progressive Supranuclear Palsy (PSP) is an incurable neurodegenerative disorder. One variant of PSP is a frontal lobe cognitive or behavioral presentation (PSP-F). Currently, the primary management of this disease is rooted in neurological rehabilitation, therefore, early, and accurate diagnosis is key. CASE REPORT: Here we present a 60-year-old man with a 2\u20133-year history of functional decline and behavioral changes. He was misdiagnosed with a late-onset psychiatric disorder. During his second inpatient admission, a full workup for neurodegenerative diseases was performed, and the patient was ultimately diagnosed with probable PSP-F. We describe his neurological rehabilitation plan, examining recommendations before and after diagnosis. RESULTS: After the neurodegenerative disorder diagnosis, the neurological rehabilitation plan, particularly PT and OT, changed drastically despite no change in clinical presentation emphasizing the value of an appropriate and early diagnosis. Furthermore, in an OT session, the patient demonstrated longitudinal improvement, emphasizing the importance of rehabilitation in these patient\u2019s lives. CONCLUSION: Increased recognition of PSP variants amongst healthcare providers will allow more patients to receive early and appropriate diagnoses, so that they can benefit maximally from their neurological rehabilitation plans, maintain quality of life and experience longer periods of functioning. Furthermore, developing PSP-specific rehabilitation guidelines are crucial for improved outcomes. Correct diagnosis will also reduce the use of inappropriate and potentially harmful medications in these populations.<\/jats:p>","DOI":"10.3233\/nre-220235","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T10:12:08Z","timestamp":1692699128000},"page":"239-247","source":"Crossref","is-referenced-by-count":3,"title":["Increasing awareness of rare PSP-F, where rehabilitation is the primary treatment: A case report"],"prefix":"10.1177","volume":"53","author":[{"given":"Anne","family":"Reisch","sequence":"first","affiliation":[{"name":"University of Connecticut, School of Medicine, Farmington, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Gerety","sequence":"additional","affiliation":[{"name":"Institute of Living, Hartford Hospital, Hartford, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Ding","sequence":"additional","affiliation":[{"name":"Institute of Living, Hartford Hospital, Hartford, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laren","family":"Narapareddy","sequence":"additional","affiliation":[{"name":"Emory University, School of Nursing, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharat R.","family":"Narapareddy","sequence":"additional","affiliation":[{"name":"Institute of Living, Hartford Hospital, Hartford, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/NRE-220235_ref1","unstructured":"Agarwal, S. , & Gilbert, R. (2022) Progressive supranuclear palsy. In StatPearls. 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perspectives","volume":"11","author":"Morris,","year":"2021","journal-title":"Frontiers in Neurology"},{"issue":"2","key":"10.3233\/NRE-220235_ref14","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/09540261.2013.763341","article-title":"Clinical diagnostic criteria and classification controversies in frontotemporal lobar degeneration","volume":"25","author":"Rascovsky,","year":"2013","journal-title":"International Review of Psychiatry (Abingdon, England)"},{"issue":"Pt 9","key":"10.3233\/NRE-220235_ref15","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1093\/brain\/awr179","article-title":"Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia","volume":"134","author":"Rascovsky,","year":"2011","journal-title":"Brain: A Journal of Neurology"},{"issue":"14","key":"10.3233\/NRE-220235_ref16","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1002\/mds.26054","article-title":"The phenotypic spectrum of 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views on exercise and structured physical activity for people with progressive supranuclear palsy","volume":"15","author":"Slade,","year":"2020","journal-title":"PloS One"},{"issue":"1","key":"10.3233\/NRE-220235_ref20","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/0269215519877235","article-title":"Exercise and physical activity for people with progressive supranuclear palsy: A systematic review","volume":"34","author":"Slade,","year":"2020","journal-title":"Clinical Rehabilitation"},{"issue":"2","key":"10.3233\/NRE-220235_ref21","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1055\/s-0034-1377058","article-title":"Progressive supranuclear palsy: A heterogeneous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia","volume":"34","author":"Steele,","year":"2014","journal-title":"Seminars in 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(2008) FDA extends black-box warning to all antipsychotics. Psychiatric News. Retrieved December 5, 2022, from https:\/\/psychnews.psychiatryonline.org\/doi\/10.1176\/pn.43.14.0001","DOI":"10.1176\/pn.43.14.0001"}],"container-title":["NeuroRehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/NRE-220235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:07:33Z","timestamp":1777615653000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/NRE-220235"}},"subtitle":[],"editor":[{"given":"Matthew E.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Lindsey J.","family":"Gurin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Davin K.","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Durga","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,9,25]]},"references-count":23,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3233\/nre-220235","relation":{},"ISSN":["1053-8135","1878-6448"],"issn-type":[{"value":"1053-8135","type":"print"},{"value":"1878-6448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,25]]}}}