{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T09:49:43Z","timestamp":1777888183154,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pediatric Rehabilitation Medicine"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>With advances in the treatment of the mucopolysaccharidosis (MPS)\n\t\t\t disorders, musculoskeletal problems are increasingly becoming a focus of care\n\t\t\t for these patients. This review discusses the current understanding of the\n\t\t\t pathophysiology of musculoskeletal disease in MPS and its orthopedic\n\t\t\t management. Deformities of the spine, hips and extremities are common and often\n\t\t\t functionally limiting. Carpal tunnel syndrome and flexor tendon triggering are\n\t\t\t common. Surgical intervention is often required to optimize long-term\n\t\t\t function.<\/jats:p>","DOI":"10.3233\/prm-2010-0102","type":"journal-article","created":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T17:06:59Z","timestamp":1575392819000},"page":"47-56","source":"Crossref","is-referenced-by-count":38,"title":["Orthopedic management of mucopolysaccharide disease"],"prefix":"10.1177","volume":"3","author":[{"given":"Klane K.","family":"White","sequence":"first","affiliation":[{"name":"Seattle Children's Hospital, Department of Orthopedic\r\t\t\t Surgery, Seattle, WA, USA"},{"name":"University of Washington, Department of Orthopedics\r\t\t\t and Sports Medicine, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Harmatz","sequence":"additional","affiliation":[{"name":"Children's Hospital &amp; Research Center Oakland,\r\t\t\t Oakland, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,1]]},"container-title":["Journal of Pediatric Rehabilitation Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/PRM-2010-0102","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/PRM-2010-0102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:38:14Z","timestamp":1777610294000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/PRM-2010-0102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.3233\/PRM-2010-0102"],"URL":"https:\/\/doi.org\/10.3233\/prm-2010-0102","relation":{},"ISSN":["1874-5393","1875-8894"],"issn-type":[{"value":"1874-5393","type":"print"},{"value":"1875-8894","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}