{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T09:50:24Z","timestamp":1777888224701,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PRM"],"published-print":{"date-parts":[[2023,9,19]]},"abstract":"<jats:p>PURPOSE: This study aimed to compare the result of the six-minute walk test (6MWT) in patients with cystic fibrosis (CF) aged\u200a&lt;\u200a20 years old and individuals without CF. METHODS: In this cross-sectional study, 50 children and adolescents with CF and 20 children and adolescents without CF underwent the 6MWT. Vital signs before and immediately after the 6MWT and six-minute walk distance (6MWD) were evaluated. RESULTS: The mean change in heart rate, percentage of peripheral oxygen saturation (SpO2%), systolic blood pressure, respiratory rate, and dyspnea severity during the 6MWT was significantly higher in patients with CF. In the case group, 6MWD was associated with regular chest physical therapy (CPT) and forced expiratory volume (FEV)&gt;\u200a80%. Patients with CF receiving regular CPT or mechanical vibration and with FEV in the first second\u200a&gt;\u200a80% showed better physical capacity during the 6MWT (smaller Sp02% decline and lower dyspnea perception). CONCLUSION: Children and adolescents with CF have lower physical capacity compared to individuals without CF. CPT and mechanical vibration could be used to increase physical capacity in this population.<\/jats:p>","DOI":"10.3233\/prm-210089","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T12:02:38Z","timestamp":1680264158000},"page":"517-528","source":"Crossref","is-referenced-by-count":0,"title":["Six-minute walk test and factors affecting exercise capacity in children with cystic fibrosis"],"prefix":"10.1177","volume":"16","author":[{"given":"Vahideh","family":"Toopchizadeh","sequence":"first","affiliation":[{"name":"Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaheh","family":"Nezamoleslami","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandana","family":"Rafeey","sequence":"additional","affiliation":[{"name":"Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Jahanjoo","sequence":"additional","affiliation":[{"name":"Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Sadegh","family":"Khabbaz","sequence":"additional","affiliation":[{"name":"Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir Hossein","family":"Jafari-Rouhi","sequence":"additional","affiliation":[{"name":"Pediatric Health Research Center, Tabriz Children\u2019s Hospital, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"6-7","key":"10.3233\/PRM-210089_ref1","doi-asserted-by":"publisher","first-page":"217","DOI":"10.3109\/09638289809166732","article-title":"The management of young adults with cystic fibrosis: \u2018genes, jeans and genies\u2019","volume":"20","author":"Elborn","year":"1998","journal-title":"Disabil Rehabil"},{"key":"10.3233\/PRM-210089_ref2","unstructured":"Savant A , Lyman B , Bojanowski C , Upadia J Cystic Fibrosis In: Adam MP Everman DB Mirzaa GM et al editors. 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