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In this article, baclofen use for spasticity management in children is briefly reviewed along with discussion of approaches using other medications as first-line treatment options. I will present a rationale for medication selection for spasticity management and discuss the approaches I take in medication selection that incorporate spasticity severity, patient goals, and medication side effect profiles.<\/jats:p>","DOI":"10.3233\/prm-230001","type":"journal-article","created":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T12:40:59Z","timestamp":1679056859000},"page":"11-17","source":"Crossref","is-referenced-by-count":5,"title":["Is baclofen the least worst option for spasticity management in children?"],"prefix":"10.1177","volume":"16","author":[{"given":"Joline E.","family":"Brandenburg","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation & Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"3","key":"10.3233\/PRM-230001_ref1","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1152\/physiol.00054.2018","article-title":"A Critical Evaluation of Current Concepts in Cerebral Palsy","volume":"34","author":"Brandenburg","year":"2019","journal-title":"Physiology (Bethesda)"},{"issue":"2","key":"10.3233\/PRM-230001_ref2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s11910-020-1022-z","article-title":"State of the Evidence Traffic Lights Systematic Review of Interventions for Preventing and Treating Children with Cerebral Palsy","volume":"20","author":"Novak","year":"2020","journal-title":"Curr Neurol Neurosci Re3"},{"issue":"3","key":"10.3233\/PRM-230001_ref4","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1152\/physrev.00036.2003","article-title":"Molecular Structure and Physiological Functions of GABAB Receptors","volume":"84","author":"Bettler","year":"2004","journal-title":"Physiol Rev"},{"issue":"8","key":"10.3233\/PRM-230001_ref5","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1212\/WNL.0b013e318247cd03","article-title":"GABAB receptors","volume":"78","author":"Benarroch","year":"2012","journal-title":"Structure, functions, and clinical implications. 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