{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T09:55:26Z","timestamp":1777888526129,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Restorative Neurology and Neuroscience"],"published-print":{"date-parts":[[2016,11,22]]},"abstract":"<jats:p>Background: A large number of patients with Bell\u2019s palsy fail to recover facial function completely after steroid therapy. Only a few small trials have been conducted to test whether outcomes can be improved by the addition of antiviral therapy.<\/jats:p>\n                  <jats:p>Objective: To evaluate the efficacy of treatment with steroid alone versus steroid + antiviral in a group of patients with moderately severe to severe acute Bell\u2019s palsy.<\/jats:p>\n                  <jats:p>Methods: Fifty eligible patients out of a total of 65 with acute onset Bell\u2019s palsy were randomized to receive the two treatments. Evaluation was performed before starting treatment, after 2 weeks of treatment and 3 months after onset, using the House and Brackmann facial nerve grading system (HB) and the Sunnybrook grading system.<\/jats:p>\n                  <jats:p>This study was registered with ClinicalTrials.gov, number NCT02328079.<\/jats:p>\n                  <jats:p>Results: Both treatments had comparable demographics and clinical scores at baseline. There was greater improvement in the mean HB and Sunnybrook scores of the steroid + antiviral group in comparison to steroid group at 3 months. At the end of the 3rd month, 17 patients (68%) had good recovery and 8 patients (32%) had poor recovery in the steroid group compared with 23 patients (92%) and 2 (8%) respectively in the steroid and antiviral group ( p\u200a=\u200a0.034).<\/jats:p>\n                  <jats:p>Conclusion: The combination of steroid and antiviral treatment increases the possibility of recovery in moderately severe to complete acute Bell\u2019s palsy.<\/jats:p>","DOI":"10.3233\/rnn-150605","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T08:49:09Z","timestamp":1475225349000},"page":"897-905","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Steroid\/Antiviral for the treatment of Bell\u2019s palsy: Double blind randomized clinical trial"],"prefix":"10.1177","volume":"34","author":[{"given":"Eman Mohamed","family":"Khedr","sequence":"first","affiliation":[{"name":"Department of Neuropsychiatry, Assiut University Hospital, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reda","family":"Badry","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry, Assiut University Hospital, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwer Mohamed","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry, Assiut University Hospital, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noha","family":"Abo El-Fetoh","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry, Assiut University Hospital, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina Hatem","family":"El-Hammady","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Rehabilitation, Assiut University Hospital, Assiut, 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