{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T16:01:16Z","timestamp":1789920076103,"version":"4.0.1"},"reference-count":34,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T00:00:00Z","timestamp":1499299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Restorative Neurology and Neuroscience"],"published-print":{"date-parts":[[2017,8,8]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique, which can modulate cortical excitability and combined with rehabilitation therapies may improve motor recovery after stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Our aim was to study the feasibility of a 4-week robotic gait training protocol combined with tDCS, and to study tDCS to the leg versus hand motor cortex or sham to improve walking ability in patients after a subacute stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Forty-nine subacute stroke patients underwent 20 daily sessions (5 days a week for 4 weeks) of robotic gait training combined with tDCS. Patients were assigned either to the tDCS\n                      <jats:sub>leg<\/jats:sub>\n                      group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a9), receiving 2\u200amA anodal tDCS over the motor cortex leg representation (vertex), or an active control group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a17) receiving anodal tDCS over the hand motor cortex area (tDCS\n                      <jats:sub>hand<\/jats:sub>\n                      ). In addition, we studied 23 matched patients in a control group receiving gait training without tDCS (\n                      <jats:sub>no<\/jats:sub>\n                      tDCS). Study outcomes included gait speed (10-meter walking test), and quality of gait, using the Functional Ambulatory Category (FAC) before and after the 4-week training period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Only one patient did not complete the treatment because he presented a minor side-effect. Patients in all three groups showed a significantly improvement in gait speed and FAC. The tDCS\n                      <jats:sub>leg<\/jats:sub>\n                      group did not perform better than the tDCS\n                      <jats:sub>hand<\/jats:sub>\n                      or\n                      <jats:sub>no<\/jats:sub>\n                      tDCS group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Combined tDCS and robotic training is a safe and feasible procedure in subacute stroke patients. However, adding tDCS to robot-assisted gait training shows no benefit over robotic gait training alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/rnn-170734","type":"journal-article","created":{"date-parts":[[2017,7,7]],"date-time":"2017-07-07T11:49:24Z","timestamp":1499428164000},"page":"377-384","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["tDCS does not enhance the effects of robot-assisted gait training in patients with subacute stroke"],"prefix":"10.1177","volume":"35","author":[{"given":"Daniel","family":"Leon","sequence":"first","affiliation":[{"name":"Fundaci\u00f3n Institut Guttmann, Institut Universitari de Neurorehabilitaci\u00f3 adscrit a la UAB, Badalona \u2013Barcelona, Spain"},{"name":"Univ Autonoma de Barcelona, Bellaterra (Cerdanyola del Vall\u00e8s), Spain"},{"name":"Fundaci\u00f3 Institut d\u2019Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol, Badalona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Cortes","sequence":"additional","affiliation":[{"name":"Burke Medical Research Institute","place":["USA"]},{"name":"Department of Rehabilitation Medicine, Weill Cornell Medicine, New York, NY, USA"},{"name":"Universitat de Barcelona, Gran Via de les Corts Catalanes, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Elder","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice","family":"Kumru","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Institut Guttmann, Institut Universitari de Neurorehabilitaci\u00f3 adscrit a la UAB, Badalona \u2013Barcelona, Spain"},{"name":"Univ Autonoma de Barcelona, Bellaterra (Cerdanyola del Vall\u00e8s), Spain"},{"name":"Fundaci\u00f3 Institut d\u2019Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol, Badalona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Laxe","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Institut Guttmann, Institut Universitari de Neurorehabilitaci\u00f3 adscrit a la UAB, Badalona \u2013Barcelona, Spain"},{"name":"Univ Autonoma de Barcelona, Bellaterra (Cerdanyola del Vall\u00e8s), Spain"},{"name":"Fundaci\u00f3 Institut d\u2019Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol, Badalona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan James","family":"Edwards","sequence":"additional","affiliation":[{"name":"Burke Medical Research Institute","place":["USA"]},{"name":"Department of Neurology, Weill Cornell Medicine, New York, NY, USA"},{"name":"Edith Cowan University","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep Maria","family":"Tormos","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Institut Guttmann, Institut Universitari de Neurorehabilitaci\u00f3 adscrit a la UAB, Badalona \u2013Barcelona, Spain"},{"name":"Univ Autonoma de Barcelona, Bellaterra (Cerdanyola del Vall\u00e8s), Spain"},{"name":"Fundaci\u00f3 Institut d\u2019Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol, Badalona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Bernabeu","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Institut Guttmann, Institut Universitari de Neurorehabilitaci\u00f3 adscrit a la UAB, Badalona \u2013Barcelona, Spain"},{"name":"Univ Autonoma de Barcelona, Bellaterra (Cerdanyola del Vall\u00e8s), Spain"},{"name":"Fundaci\u00f3 Institut d\u2019Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol, Badalona, 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