{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:41:31Z","timestamp":1770979291725,"version":"3.50.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686509","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,12]]},"abstract":"<jats:p>The opioid crisis in Ontario continues to drive high rates of opioid-related mortality, exacerbated by a toxic drug supply and fragmented healthcare services. Emergency departments represent critical intervention points but currently lack standardized, real-time mechanisms to identify and coordinate care for patients at risk of opioid toxicity. This study proposes the Opioid Predictive &amp; Analytics Linkage (OPAL) framework, a standardized prevention model integrating predictive risk detection, multi-provider notifications, an evidence-based opioid care pathway, and post-discharge referral tracking to prevent opioid-related deaths. Stakeholder engagement suggests OPAL is both feasible and operationally sustainable within Ontario\u2019s healthcare infrastructure. Implementing and evaluating OPAL in real-world clinical settings may enhance early intervention, continuity of care, and ultimately reduce preventable opioid-related deaths across the province.<\/jats:p>","DOI":"10.3233\/shti260014","type":"book-chapter","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:54:16Z","timestamp":1770976456000},"source":"Crossref","is-referenced-by-count":0,"title":["Design and Evaluation of a Standardized Opioid Toxicity Prevention Pathway for Ontario"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9843-2885","authenticated-orcid":false,"given":"Ishan","family":"Aditya","sequence":"first","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8099-6941","authenticated-orcid":false,"given":"Kathleen","family":"Bissonnette","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3492-2124","authenticated-orcid":false,"given":"Sana","family":"Khushk","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2986-8369","authenticated-orcid":false,"given":"Noopur","family":"Swadas","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","From Silos to Synergy: Building Bridges"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI260014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:54:16Z","timestamp":1770976456000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI260014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,12]]},"ISBN":["9781643686509"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti260014","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,12]]}}}