{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:36:28Z","timestamp":1779402988096,"version":"3.53.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686615","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,21]]},"abstract":"<jats:p>Due to anatomical variability and imaging heterogeneity, the choice of loss function for breast, fibroglandular tissue (FGT), and implant segmentation in magnetic resonance imaging (MRI) is a challenging task. This study compares three loss function strategies for image segmentation: a baseline model using the standard Dice + cross-entropy loss, the Skeleton Recall Loss (SRL) targeting fine structural details, and a novel Volume-Aware Loss (VAL) penalizing implausibly small or false-positive implant predictions. A total of 136 pre-contrast T1-weighted breast MRI volumes were used for 5-fold cross-validation. The baseline achieved the highest overall performance (mean DSC: 0.921 breast, 0.712 FGT, 0.933 implant), while SRL and VAL were comparable to the baseline within the statistical variance of the dataset. Thus, we deduced that the standard Dice + cross-entropy loss remains the gold-standard for heterogeneous breast MRI segmentation.<\/jats:p>","DOI":"10.3233\/shti260136","type":"book-chapter","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T21:56:16Z","timestamp":1779400576000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Loss Functions for Fibroglandular Tissue Segmentation in MRI"],"prefix":"10.3233","author":[{"given":"Alexia","family":"Rizoudis","sequence":"first","affiliation":[{"name":"IT-Infrastructure for Translational Medical Research, University of Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona","family":"Wudy","sequence":"additional","affiliation":[{"name":"Department of diagnostic and interventional Radiology and Neuroradiology, University Hospital Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl Mathis","family":"Wild","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Hospital Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Kramer","sequence":"additional","affiliation":[{"name":"IT-Infrastructure for Translational Medical Research, University of Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Ditsch","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Hospital Augsburg, Germany"},{"name":"Bavarian Center for Cancer Research (BZKF), Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Wendler","sequence":"additional","affiliation":[{"name":"Department of diagnostic and interventional Radiology and Neuroradiology, University Hospital Augsburg, Germany"},{"name":"Digital Medicine, University Hospital Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"IT-Infrastructure for Translational Medical Research, University of Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Opening the Personal Gate between Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI260136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T21:56:16Z","timestamp":1779400576000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI260136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"ISBN":["9781643686615"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti260136","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,21]]}}}