{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:41:37Z","timestamp":1779403297824,"version":"3.53.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686615","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,21]]},"abstract":"<jats:p>To explore the potential of ontologies in improving adverse event identification, we developed ontology-aligned representations of adverse events extracted from electronic health records (EHRs) of fifty patients participating in a multiple myeloma trial. We reused relevant biomedical ontologies that are built upon Basic Formal Ontology (BFO) and constructed representations in Resource Description Framework\/Web Ontology Language (RDF\/OWL). Adverse events for the selected cohort were extracted from both structured and unstructured EHR data stored in the Arkansas Clinical Data Repository (AR-CDR). This ontology-aligned approach supports automated reasoning and facilitates semantic interoperability.<\/jats:p>","DOI":"10.3233\/shti260397","type":"book-chapter","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:03:44Z","timestamp":1779401024000},"source":"Crossref","is-referenced-by-count":0,"title":["Ontology-Aligned Representation of Adverse Events in a Multiple Myeloma Clinical Trial"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3960-8868","authenticated-orcid":false,"given":"Mitra","family":"Rocca","sequence":"first","affiliation":[{"name":"University of Arkansas for Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1834-3856","authenticated-orcid":false,"given":"Mathias","family":"Brochhausen","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9150-1326","authenticated-orcid":false,"given":"Michael","family":"Buckley","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1402-9616","authenticated-orcid":false,"given":"Jonathan P.","family":"Bona","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Opening the Personal Gate between Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI260397","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:03:44Z","timestamp":1779401024000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI260397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"ISBN":["9781643686615"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti260397","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,21]]}}}