{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T23:06:21Z","timestamp":1779404781609,"version":"3.53.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686615","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,21]]},"abstract":"<jats:p>Catheter-related bloodstream infections (CRBSIs) are often difficult to diagnose due to the variability of pathogen sources and inconsistencies in laboratory data. Differential time to positivity (DTP) offers a means to distinguish CRBSIs from secondary bacteremia, but its practical application is complicated by heterogeneous nomenclature and variable reporting formats. We implemented an algorithm that standardizes microbiological records using a custom ontology-driven framework and applies clinically established thresholds. A fuzzy matching approach was then used to classify infections as likely catheter-related, unlikely, or non-diagnostic. This proof-of-concept validates the feasibility of automated DTP analysis and highlights the potential of semantic technologies to support clinical decision-making.<\/jats:p>","DOI":"10.3233\/shti260512","type":"book-chapter","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:07:08Z","timestamp":1779401228000},"source":"Crossref","is-referenced-by-count":0,"title":["Automated Differential Time to Positivity Analysis for CRBSIs Using Historical Microbiological Data"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5416-6417","authenticated-orcid":false,"given":"Julia","family":"Liepold","sequence":"first","affiliation":[{"name":"Institute for Logic and Computation, TU Wien, 1040 Vienna, Austria"},{"name":"Medexter Healthcare, Borschkegasse 7\/5, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5902-4666","authenticated-orcid":false,"given":"Leonhard","family":"Hauptfeld","sequence":"additional","affiliation":[{"name":"Medexter Healthcare, Borschkegasse 7\/5, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7867-9465","authenticated-orcid":false,"given":"Moritz","family":"Grob","sequence":"additional","affiliation":[{"name":"Medexter Healthcare, Borschkegasse 7\/5, 1090 Vienna, Austria"},{"name":"Medical University of Vienna, Center for Medical Data Science, Institute of Artificial Intelligence, Spitalgasse 23, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Csarmann","sequence":"additional","affiliation":[{"name":"Medexter Healthcare, Borschkegasse 7\/5, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0345-4011","authenticated-orcid":false,"given":"Andrea","family":"Rappelsberger","sequence":"additional","affiliation":[{"name":"Medical University of Vienna, Center for Medical Data Science, Institute of Artificial Intelligence, Spitalgasse 23, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5046-1549","authenticated-orcid":false,"given":"Klaus-Peter","family":"Adlassnig","sequence":"additional","affiliation":[{"name":"Medexter Healthcare, Borschkegasse 7\/5, 1090 Vienna, Austria"},{"name":"Medical University of Vienna, Center for Medical Data Science, Institute of Artificial Intelligence, Spitalgasse 23, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Opening the Personal Gate between Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI260512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:07:08Z","timestamp":1779401228000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI260512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"ISBN":["9781643686615"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti260512","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,21]]}}}