{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:37:02Z","timestamp":1777891022838,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2021,3,12]]},"abstract":"<jats:p>BACKGROUND: Status epilepticus (SE) as the initial presentation of aortic dissection in the absence of chest pain is very rare. We report a case of aortic dissection (AD), which presented as SE with markedly elevated levels of D-dimer, a reliable and sensitive index of fibrin deposition and stabilization. CASE REPORT: A 74-year-old Asian woman presented to the emergency department (ED) with an altered mental state following three consecutive generalized tonic-clonic seizures at home. Her initial vital signs were normal, and the head CT scan was non-informative. Most of the laboratory results were normal, but the D-dimer levels were markedly elevated. About 90 minutes after arriving at the ED, the patient developed another tonic-clonic seizure for about three-four minutes. Emergent chest CT revealed type A AD with hemopericardium. During preparation for the emergency operation, the patient suffered a cardiac arrest. Despite performing cardiopulmonary resuscitation (CPR) for 35 minutes, the patient died. CONCLUSIONS: The goal of this case report is to make clinicians aware of the possibility that new-onset SE with elevated D-dimer levels can be an indication of acute AD type A in the absence of typical symptoms.<\/jats:p>","DOI":"10.3233\/thc-202309","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T12:12:46Z","timestamp":1592568766000},"page":"357-360","source":"Crossref","is-referenced-by-count":0,"title":["Status epilepticus as an initial presentation of aortic dissection: A case report"],"prefix":"10.1177","volume":"29","author":[{"given":"In Hwan","family":"Yeo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Kun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/THC-202309_ref1","doi-asserted-by":"publisher","first-page":"2611","DOI":"10.1161\/circulationaha.106.630400","article-title":"Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from 1987\u20132002","volume":"114","author":"Olsson","year":"2006","journal-title":"Circulation"},{"key":"10.3233\/THC-202309_ref2","doi-asserted-by":"publisher","first-page":"2806","DOI":"10.1016\/j.ijcard.2012.07.008","article-title":"Acute aortic dissection: epidemiology and outcomes","volume":"167","author":"Pacini","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.3233\/THC-202309_ref3","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1161\/01.str.0000254594.33408.b1","article-title":"Neurological symptoms in type A aortic dissections","volume":"38","author":"Gaul","year":"2007","journal-title":"Stroke"},{"key":"10.3233\/THC-202309_ref4","doi-asserted-by":"publisher","first-page":"245.e1-2","DOI":"10.1016\/j.ajem.2007.03.026","article-title":"Seizure: an unusual primary presentation of type A aortic dissection","volume":"26","author":"Mo","year":"2008","journal-title":"Am J Emerg Med"},{"key":"10.3233\/THC-202309_ref5","doi-asserted-by":"publisher","first-page":"e31-3","DOI":"10.1212\/WNL.0b013e31820d6271","article-title":"Pearls & oy-sters: a stroke of luck: detecting type A aortic dissection by MRA","volume":"76","author":"Hyland","year":"2011","journal-title":"Neurology"},{"key":"10.3233\/THC-202309_ref6","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1093\/eurheartj\/ehm484","article-title":"D-dimer in ruling out acute aortic dissection: a systematic review and prospective cohort study","volume":"28","author":"Sodeck","year":"2007","journal-title":"Eur Heart J"},{"key":"10.3233\/THC-202309_ref7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.ejim.2013.07.012","article-title":"Causes of elevated D-dimer in patients admitted to a large urban emergency department","volume":"25","author":"Lippi","year":"2014","journal-title":"Eur J Intern Med"},{"key":"10.3233\/THC-202309_ref8","doi-asserted-by":"publisher","first-page":"2702","DOI":"10.1161\/circulationaha.108.833004","article-title":"Diagnosis of acute aortic dissection by D-dimer: the international registry of acute aortic dissection substudy on biomarkers (IRAD-Bio) experience","volume":"119","author":"Suzuki","year":"2009","journal-title":"Circulation"},{"key":"10.3233\/THC-202309_ref9","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.annemergmed.2015.02.013","article-title":"A systematic review and meta-analysis of D-dimer as a rule-out test for suspected acute aortic dissection","volume":"66","author":"Asha","year":"2015","journal-title":"Ann Emerg Med"}],"container-title":["Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/THC-202309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:52:08Z","timestamp":1777614728000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/THC-202309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,12]]},"references-count":9,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3233\/thc-202309","relation":{},"ISSN":["0928-7329","1878-7401"],"issn-type":[{"value":"0928-7329","type":"print"},{"value":"1878-7401","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,12]]}}}