{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T05:18:01Z","timestamp":1737091081009,"version":"3.33.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2021,9,6]]},"abstract":"<jats:p>BACKGROUND: The mucous membrane of the maxillary sinus is sensitivis susceptible to infection or inflammation adjacent to it, which may contribute to mucous membrane thickening (MMT). Residual alveolar bone quality (RABQ) is considered a quality of the remaining bone apical to periodontal defect adjoining to the floor of the maxillary sinus. OBJECTIVE: The current study aimed to analyze the minimum RABQ to prevent the extension of periodontal pathology from reaching maxillary sinus using cone-beam computed tomography (CBCT). METHODS: In this retrospective observational study, 240 sinus exposure CBCT records of 146 patients were evaluated. Patients with at least one sinus exposure were included. RABQ and MMT were calculated using CBCT inbuilt tools. RABQ was divided into four groups based on gray scale values (GSV). Statistical analysis was performed using one way ANOVA and independent sample t-tests. Correlation was completed applying Pearson\u2019s correlation coefficient. RESULTS: A significant difference (p&lt; 0.05) was observed between the MMT values of the four RABQ groups. Inverse correlation was observed between mean MMT and GSV values. Mean MMT was higher than pathological MMT range (&gt; 2\u00a0mm), with significant differences in groups A and B, where mean GSV values are less than 500. Mean GSV greater than 500 in groups C and D show non-pathological MMT. Prevalence of MMT is 91.4% if GSV is &lt; 500 and 7.5% if GSV is &gt; 500. CONCLUSIONS: Our study suggests that MMT is present if RABQ has GSV values &lt; 500. Maxillary sinusitis and its etiology from periodontal pathology can be excluded based on RABQ adjoining periodontal lesion. Early detection and prompt treatment along with appropriate regenerative protocols can be performed to increase the RABQ. Further microbiological investigation is required to support the present results.<\/jats:p>","DOI":"10.3233\/thc-202577","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T18:20:38Z","timestamp":1611080438000},"page":"911-920","source":"Crossref","is-referenced-by-count":3,"title":["Does the quality of residual alveolar bone apical to a periodontal lesion beneath the maxillary sinus play a vital role in preventing the extension of periodontal disease to maxillary sinus? A CBCT-assisted retrospective study"],"prefix":"10.1177","volume":"29","author":[{"given":"Vijay","family":"Apparaju","sequence":"first","affiliation":[{"name":"Periodontist and Oral Implantologist, Hayati Asnany, Sabya, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil Kumar","family":"Vaddamanu","sequence":"additional","affiliation":[{"name":"Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhupesh Kiran","family":"Mandali","sequence":"additional","affiliation":[{"name":"Resident at North West Dental Residency, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishwanath","family":"Gurumurthy","sequence":"additional","affiliation":[{"name":"Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soumya","family":"Vishwanath","sequence":"additional","affiliation":[{"name":"All Care Dental Center, Bengaluru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"6","key":"10.3233\/THC-202577_ref1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/idj.12186","article-title":"Significance of maxillary sinus mucosal thickening in patients with periodontal disease","volume":"65","author":"Ren","year":"2015","journal-title":"Int Dent J."},{"issue":"1","key":"10.3233\/THC-202577_ref2","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.4317\/medoral.23172","article-title":"Association between maxillary sinus pathology and odontogenic lesions in patients evaluated by cone beam computed tomography. A systematic review and meta-analysis","volume":"25","author":"Pe\u00f1arrocha-Oltra","year":"2020","journal-title":"Med Oral Patol Oral Cir Bucal."},{"issue":"8","key":"10.3233\/THC-202577_ref3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1902\/jop.1984.55.8.477","article-title":"The relationship between periodontitis and the maxillary sinus","volume":"55","author":"Lane","year":"1984","journal-title":"J Periodontol."},{"issue":"10","key":"10.3233\/THC-202577_ref4","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.joen.2016.07.003","article-title":"Association between odontogenic conditions and maxillary sinus disease: A study using cone-beam computed tomography","volume":"42","author":"Nascimento","year":"2016","journal-title":"J Endod."},{"issue":"1","key":"10.3233\/THC-202577_ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40902-018-0186-9","article-title":"Definition and management of odontogenic maxillary sinusitis","volume":"41","author":"Kim","year":"2019","journal-title":"Maxillofac Plast Reconstr Surg."},{"issue":"11","key":"10.3233\/THC-202577_ref6","first-page":"591","article-title":"Maxillary sinusitis of odontogenic origin","volume":"34","author":"Maloney","year":"1968","journal-title":"J Can Dent Assoc."},{"issue":"8","key":"10.3233\/THC-202577_ref7","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1902\/jop.1992.63.8.674","article-title":"A histomorphologic study of the effects of periodontal inflammation on the maxillary sinus mucosa","volume":"63","author":"Moskow","year":"1992","journal-title":"J Periodontol."},{"issue":"3","key":"10.3233\/THC-202577_ref8","doi-asserted-by":"crossref","first-page":"166","DOI":"10.15171\/joddd.2018.026","article-title":"Effect of periodontal therapy on maxillary sinus mucous membrane thickening in chronic periodontitis: A split-mouth study","volume":"26","author":"Lathiya","year":"2018","journal-title":"J Dent Res Dent Clin Dent Prospects."},{"issue":"1","key":"10.3233\/THC-202577_ref9","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1902\/jop.2006.77.1.129","article-title":"Maxillary sinusitis and periapical abscess following periodontal therapy: A case report using three-dimensional evaluation","volume":"77","author":"Huang","year":"2006","journal-title":"J Periodontol."},{"issue":"3","key":"10.3233\/THC-202577_ref10","doi-asserted-by":"crossref","first-page":"e80","DOI":"10.1016\/j.tripleo.2009.10.031","article-title":"Prevalence of mucosal abnormalities of the maxillary sinus and their relationship to dental disease in panoramic radiography: results from the Health 2000 Health Examination Survey","volume":"109","author":"Vallo","year":"2010","journal-title":"Oral SurgeryOral Med Oral Pathol Oral Radiol Endodontology."},{"issue":"4","key":"10.3233\/THC-202577_ref11","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4103\/1735-3327.261131","article-title":"Does residual bone thickness apical to periodontal defect play a major role in maxillary sinus mucous membrane thickness? A cone-beam computed tomography-assisted retrospective study","volume":"16","author":"Apparaju","year":"2019","journal-title":"Dent Res J."},{"issue":"2","key":"10.3233\/THC-202577_ref12","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0030-6665(03)00171-3","article-title":"Maxillary sinus disease of odontogenic origin","volume":"37","author":"Mehra","year":"2004","journal-title":"Otolaryngologic Clinics of North America."},{"issue":"5","key":"10.3233\/THC-202577_ref13","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.2214\/ajr.166.5.8615273","article-title":"Dental disease: A frequently unrecognized cause of maxillary sinus abnormalities","volume":"166","author":"Abrahams","year":"1996","journal-title":"Am J Roentgenol."},{"key":"10.3233\/THC-202577_ref14","first-page":"1096365","article-title":"Presurgical cone beam computed tomography bone quality evaluation for predictable immediate implant placement and restoration in esthetic zone","volume":"2017","author":"Cristache","year":"2017","journal-title":"Case Rep Dent."},{"issue":"1","key":"10.3233\/THC-202577_ref15","doi-asserted-by":"crossref","first-page":"20140238","DOI":"10.1259\/dmfr.20140238","article-title":"CBCT-based bone quality assessment: Are Hounsfield units applicable","volume":"44","author":"Pauwels","year":"2015","journal-title":"Dentomaxillofacial Radiology."},{"issue":"1","key":"10.3233\/THC-202577_ref16","doi-asserted-by":"crossref","first-page":"20120075","DOI":"10.1259\/dmfr.20120075","article-title":"Diagnostic imaging of trabecular bone microstructure for oral implants: A literature review","volume":"42","author":"Ibrahim","year":"2013","journal-title":"Dentomaxillofacial Radiology."},{"issue":"6","key":"10.3233\/THC-202577_ref17","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.oooo.2014.02.012","article-title":"Internal or in-scan validation: a method to assess CBCT and MSCT gray scales using a human cadaver","volume":"117","author":"Bujt\u00e1r","year":"2014","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol."},{"issue":"5","key":"10.3233\/THC-202577_ref18","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1600-0501.2008.01672.x","article-title":"Evaluation of voxel values in mandibular cancellous bone: Relationship between cone-beam computed tomography and multislice helical computed tomography","volume":"20","author":"Naitoh","year":"2009","journal-title":"Clin Oral Implants Res."},{"issue":"1","key":"10.3233\/THC-202577_ref19","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1016\/j.tripleo.2009.08.027","article-title":"Comparison between cone-beam and multislice computed tomography depicting mandibular neurovascular canal structures","volume":"109","author":"Naitoh","year":"2010","journal-title":"Oral Surgery, Oral Med Oral Pathol Oral Radiol Endodontology."},{"issue":"2","key":"10.3233\/THC-202577_ref20","first-page":"239","article-title":"Measurement of mandibles with microfocus x-ray computerized tomography and compact computerized tomography for dental use","volume":"19","author":"Naitoh","year":"2004","journal-title":"Int J Oral Maxillofac Implants."},{"issue":"8","key":"10.3233\/THC-202577_ref21","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1111\/j.1600-0501.2011.02390.x","article-title":"The reliability of cone-beam computed tomography to assess bone density at dental implant recipient sites: A histomorphometric analysis by micro-CT","volume":"24","author":"Gonz\u00e1lez-Garc\u00eda","year":"2013","journal-title":"Clin Oral Implants Res."},{"issue":"6","key":"10.3233\/THC-202577_ref22","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/clr.12133","article-title":"Comparison between microcomputed tomography and cone-beam computed tomography radiologic bone to assess atrophic posterior maxilla density and microarchitecture","volume":"25","author":"Monje","year":"2014","journal-title":"Clin Oral Implants Res."},{"issue":"5","key":"10.3233\/THC-202577_ref23","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1600-0501.2009.01896.x","article-title":"Reliability of voxel values from cone-beam computed tomography for dental use in evaluating bone mineral density","volume":"21","author":"Nomura","year":"2010","journal-title":"Clin Oral Implants Res."},{"issue":"2","key":"10.3233\/THC-202577_ref24","first-page":"208","article-title":"Bone density assessments of dental implant sites: 3. Bone quality evaluation during osteotomy and implant placement","volume":"22","author":"Lee","year":"2007","journal-title":"Int J Oral Maxillofac Implants."},{"issue":"4","key":"10.3233\/THC-202577_ref25","first-page":"713","article-title":"Cone beam computed tomography as a method of quantitative and qualitative analysis of alveolar crest in the frontal mandibular area","volume":"51","author":"Georgescu","year":"2010","journal-title":"Rom J Morphol Embryol."},{"issue":"3","key":"10.3233\/THC-202577_ref26","first-page":"416","article-title":"Bone density assessments of dental implant sites: 2. Quantitative cone-beam computerized tomography","volume":"20","author":"Aranyarachkul","year":"2005","journal-title":"Int J Oral Maxillofac Implants."},{"issue":"5","key":"10.3233\/THC-202577_ref27","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1902\/jop.2011.110376","article-title":"Cone-Beam Computed Tomographic Evidence of the Association Between Periodontal Bone Loss and Mucosal Thickening of the Maxillary Sinus","volume":"83","author":"Phothikhun","year":"2012","journal-title":"J Periodontol."},{"issue":"1","key":"10.3233\/THC-202577_ref28","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.tripleo.2006.01.001","article-title":"Limited cone-beam CT and intraoral radiography for the diagnosis of periapical pathology","volume":"103","author":"Lofthag-Hansen","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod."},{"issue":"3","key":"10.3233\/THC-202577_ref29","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1600-051X.1986.tb01463.x","article-title":"The effects of periodontal treatment on mucous membrane thickening in the maxillary sinus","volume":"13","author":"Falk","year":"1986","journal-title":"J Clin Periodontol."},{"issue":"9","key":"10.3233\/THC-202577_ref30","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1902\/jop.1988.59.9.604","article-title":"Radiographic evaluation of the effect of initial periodontal therapy on thickness of the maxillary sinus mucosa","volume":"59","author":"Engstr\u00f6m","year":"1988","journal-title":"J Periodontol."},{"key":"10.3233\/THC-202577_ref31","doi-asserted-by":"crossref","first-page":"465173","DOI":"10.1155\/2014\/465173","article-title":"Chronic Maxillary Rhinosinusitis of Dental Origin: A Systematic Review of 674 Patient Cases","volume":"2014","author":"Lechien","year":"2014","journal-title":"International Journal of Otolaryngology"}],"container-title":["Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/THC-202577","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T12:15:03Z","timestamp":1737029703000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/THC-202577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,6]]},"references-count":31,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3233\/thc-202577","relation":{},"ISSN":["0928-7329","1878-7401"],"issn-type":[{"type":"print","value":"0928-7329"},{"type":"electronic","value":"1878-7401"}],"subject":[],"published":{"date-parts":[[2021,9,6]]}}}