{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:03:58Z","timestamp":1792641838086,"version":"4.5.0"},"reference-count":43,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:00:00Z","timestamp":1694736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2023,9,15]]},"abstract":"<jats:p>BACKGROUND: Establishing baseline measurements on normative data is essential to evaluate standards of care and the impact of clinical or surgical treatments. Hand volume determination is relevant in pathological conditions where the anatomical structures might undergo modifications like post-treatment chronic edema. For example, one of the consequences of breast cancer treatment is the possibility of developing uni-lateral lymphedema on the upper limbs. OBJECTIVE: Arm and forearm volumetrics are well-studied techniques, whereas hand volumetry computation poses several challenges both from the clinical and digital perspectives. The current work has explored routine clinical and customized digital methodologies for hand volume appraisal on healthy subjects. METHODS: Clinical hand volumes computed by water displacement or circumferential measurements were compared to digital volumetry calculated from 3D laser scans. Digital volume quantification algorithms exploited the gift wrapping concept or cubic tessellation of acquired 3D shapes. This latter digital technique is parametric, and a calibration methodology to define the resolution of the tessellation has been validated. RESULTS: Results on a group of normal subjects demonstrated that the volumes computed from digital hand representations extracted by tessellation return values similar to the clinical water displacement volume assessment at low tolerances. CONCLUSIONS: The current investigation suggested that the tessellation algorithm could be considered a digital equivalent of water displacement for hand volumetrics. Future studies are needed to confirm these results in people with lymphedema.<\/jats:p>","DOI":"10.3233\/thc-220694","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T10:36:52Z","timestamp":1686307012000},"page":"1835-1854","source":"Crossref","is-referenced-by-count":6,"title":["Technical aspects and validation of custom digital algorithms for hand volumetry"],"prefix":"10.1177","volume":"31","author":[{"given":"Mauro","family":"Nascimben","sequence":"first","affiliation":[{"name":"Center for Translational Research on Autoimmune and Allergic Diseases-CAAD, Universit\u00e0 del Piemonte Orientale, Novara, Italy"},{"name":"Enginsoft SpA, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Lippi","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Universit\u00e0 del Piemonte Orientale, Novara, Italy"},{"name":"Infrastruttura Ricerca Formazione Innovazione (IRFI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Fusco","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy"},{"name":"Division of Pathology, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"de Sire","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, University of Catanzaro \u201cMagna Gr\u00e6cia\u201d, Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Invernizzi","sequence":"additional","affiliation":[{"name":"Physical and Rehabilitative Medicine, Universit\u00e0 del Piemonte Orientale, Novara, Italy"},{"name":"Infrastruttura Ricerca Formazione Innovazione (IRFI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lia","family":"Rimondini","sequence":"additional","affiliation":[{"name":"Center for Translational Research on Autoimmune and Allergic Diseases-CAAD, Universit\u00e0 del Piemonte Orientale, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"issue":"5","key":"10.3233\/THC-220694_ref1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3390\/jpm11050402","article-title":"Breast cancer-related lymphedema: Recent updates on diagnosis, severity and available treatments","volume":"11","author":"Pappalardo","year":"2021","journal-title":"Journal of Personalized Medicine."},{"issue":"1","key":"10.3233\/THC-220694_ref3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1089\/lrb.2010.0021","article-title":"Reliability and concurrent validity of the perometer for measuring hand volume in women with and without 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