{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:40:32Z","timestamp":1777891232000,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technology and Health Care"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Although the success rate of resuscitation in preterm infants is increasing, the long length of hospital stay in preterm infants and the need for more invasive operations, coupled with the widespread use of empirical antibiotics, have increased the prevalence of fungal infections in preterm infants in neonatal intensive care units (NICUs) year on year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>The present study aims to explore the risk factors of invasive fungal infections (IFI) in preterm infants and to identify some prevention strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      A total of 202 preterm infants with a gestational age of 26 weeks to 36\n                      <jats:inline-formula>\n                        <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" alttext=\"{}^{+6}\" display=\"inline\" overflow=\"scroll\">\n                          <mml:msup>\n                            <mml:mi\/>\n                            <mml:mrow>\n                              <mml:mo>+<\/mml:mo>\n                              <mml:mn>6<\/mml:mn>\n                            <\/mml:mrow>\n                          <\/mml:msup>\n                        <\/mml:math>\n                      <\/jats:inline-formula>\n                      weeks and a birth weight of less than 2,000 g, admitted to our neonatal unit during the 5-year period from January 2014 to December 2018, were selected for the study. Among these preterm infants, six cases that developed fungal infections during hospitalization were enrolled as the study group, and the remaining 196 infants who did not develop fungal infections during hospitalization were the control group. The gestational age, length of hospital stay, duration of antibiotic therapy, duration of invasive mechanical ventilation, indwelling duration of the central venous catheter, and duration of intravenous nutrition of the two groups were compared and analyzed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>There were statistically significant differences between the two groups in the gestational age, length of hospital stay, and duration of antibiotic therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>A small gestational age, a lengthy hospital stay, and long-term use of broad-spectrum antibiotics are the high-risk factors for fungal infections in preterm infants. Medical and nursing measures to address the high-risk factors might reduce the incidence of fungal infections and improve the prognosis in preterm infants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/thc-230218","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T10:37:32Z","timestamp":1686307052000},"page":"361-367","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["An analysis of the risk factors for invasive fungal infections in preterm infants and a discussion of prevention strategies"],"prefix":"10.1177","volume":"32","author":[{"given":"Lingyun","family":"Bao","sequence":"first","affiliation":[{"name":"Department of Neonatology, Kunming Children\u2019s Hospital, Kunming, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Kunming Children\u2019s Hospital, Kunming, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Kunming Children\u2019s Hospital, Kunming, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongrong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Kunming Children\u2019s Hospital, Kunming, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Kunming Children\u2019s Hospital, Kunming, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Kunming Children\u2019s Hospital, Kunming, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,1]]},"reference":[{"issue":"6","key":"e_1_3_2_2_2","first-page":"699","article-title":"Analysis of high-risk factors for secondary fungal infections in preterm infants","volume":"30","author":"Guo HC","year":"2019","unstructured":"GuoHC HuangHW. Analysis of high-risk factors for secondary fungal infections in preterm infants. Journal of Aerospace Medicine. 2019; 30(6): 699-701.","journal-title":"Journal of Aerospace Medicine."},{"key":"e_1_3_2_3_2","unstructured":"ShaoXM YeHM QiuXS. Practical Neonatology [M]. 5th edition Beijing: People\u2019s Health Publishing House. 2019: 531-533."},{"key":"e_1_3_2_4_2","unstructured":"Critical Care Medicine Branch of Chinese Medical Association Guidelines for the diagnosis and treatment of invasive fungal infections in critically ill patients (2007). Chinese Journal of Internal Medicine. 2007; 46(11): 960-966."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12323"},{"issue":"4","key":"e_1_3_2_6_2","first-page":"292","article-title":"Analysis of clinical features on neonatal invasive fungal infection","volume":"7","author":"Zheng T","year":"2019","unstructured":"ZhengT LiQP ChenHH, et al. Analysis of clinical features on neonatal invasive fungal infection. Journal of Developmental Medicine (Electronic Version). 2019; 7(4): 292-296.","journal-title":"Journal of Developmental Medicine (Electronic Version)."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.509914"},{"issue":"15","key":"e_1_3_2_8_2","first-page":"2507","article-title":"13 cases of fungal sepsis in premature infants","volume":"25","author":"Chen LD","year":"2019","unstructured":"ChenLD WangSL LiaoQ DengYH, et al. 13 cases of fungal sepsis in premature infants. International Medicine and Health Guidance News. 2019; 25(15): 2507-2509.","journal-title":"International Medicine and Health Guidance News."},{"issue":"12","key":"e_1_3_2_9_2","first-page":"911","article-title":"Diagnosis, treatment and prevention of invasive fungal infection in preterm infants","volume":"49","author":"Li QP","year":"2011","unstructured":"LiQP FengZC. Diagnosis, treatment and prevention of invasive fungal infection in preterm infants. Journal of Clinical Pediatrics. 2011; 49(12): 911-941.","journal-title":"Journal of Clinical Pediatrics."},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/ped.14085"},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","unstructured":"PradeganN Mu\u00f1ozYM ReyesM ToribioJ HerreraCJ Leon-WyssJR. Giant right atrial abscess in a premature infant with fungal endocarditis in a developing country. World J Pediatr Congenit Heart Surg. 2020 Sep; 11(5): 654-657.","DOI":"10.1177\/2150135120929009"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/bab.1908"},{"issue":"8","key":"e_1_3_2_13_2","first-page":"754","article-title":"Clinical analysis of 18 neonates with deep fungus infection under mechanical ventilation","volume":"20","author":"Li QP","year":"2005","unstructured":"LiQP HuangHY WangB, et al. Clinical analysis of 18 neonates with deep fungus infection under mechanical ventilation. Clinical Journal of Practical Pediatrics. 2005; 20(8): 754-755.","journal-title":"Clinical Journal of Practical Pediatrics."},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S227839"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2646-8"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ933"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10661-017-6051-y"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00281"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mmcr.2016.06.001"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","unstructured":"GranuloE Be\u0107arL GurbetaL Badnjevi\u0107A. Telemetry System for Diagnosis of Asthma and Chronical Obstructive Pulmonary Disease (COPD). In: Ahmed M. Begum S. Raad W. (eds) Internet of Things Technologies for HealthCare. HealthyIoT 2016. Lecture Notes of the Institute for Computer Sciences Social Informatics and Telecommunications Engineering vol 187. Springer Cham. 2016. doi: 10.1007\/978-3-319-51234-1_18.","DOI":"10.1007\/978-3-319-51234-1_18"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","unstructured":"Almina\u0160 Marijana\u0160 LemanaS et al. Review of Artificial Intelligence Application in Cardiology. 2020 9th Mediterranean Conference on Embedded Computing (MECO) Budva Montenegro 2020 pp. 1-5. doi: 10.1109\/MECO49872.2020.9134333.","DOI":"10.1109\/MECO49872.2020.9134333"},{"key":"e_1_3_2_22_2","first-page":"S336","article-title":"Artificial intelligence in medical devices: Past, present and future","volume":"33","author":"Badnjevi\u0107 A","year":"2021","unstructured":"Badnjevi\u0107A Avdihod\u017ei\u0107H Gurbeta Pokvi\u0107L. Artificial intelligence in medical devices: Past, present and future. Psychiatr Danub. 2021 May; 33(Suppl 3): S336-S341. PMID: 34010259.","journal-title":"Psychiatr Danub."},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","unstructured":"Veljovi\u0107E et al. Artificial Neural Network and Docking Study in Design and Synthesis of Xanthenes as Antimicrobial Agents. In: Badnjevic A. (eds) CMBEBIH 2017. IFMBE Proceedings vol 62. Springer Singapore. 2017. doi: 10.1007\/978-981-10-4166-2_93.","DOI":"10.1007\/978-981-10-4166-2_93"}],"updated-by":[{"DOI":"10.1177\/09287329251392360","type":"expression_of_concern","label":"Expression of concern","source":"publisher","updated":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000}}],"container-title":["Technology and Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/THC-230218","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/THC-230218","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/THC-230218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:57:42Z","timestamp":1777615062000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/THC-230218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.3233\/THC-230218"],"URL":"https:\/\/doi.org\/10.3233\/thc-230218","relation":{},"ISSN":["0928-7329","1878-7401"],"issn-type":[{"value":"0928-7329","type":"print"},{"value":"1878-7401","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]}}}