{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:40:37Z","timestamp":1777891237605,"version":"3.51.4"},"reference-count":52,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2024,3,14]]},"abstract":"<jats:p>BACKGROUND: Orthotopic urinary diversion is the preferred diversion after cystectomy. Neobladder reconstruction with a longer ileum segment (60 cm) is advantageous for obtaining a large capacity and continence at the beginning; however, the long-term risk of residual urine, chronic infection, and the need for intermittent catheterization is more pronounced with the neobladder constructed with a longer ileal segment compared to the neobladder tailored from the shorter ileal segment. OBJECTIVE: To establish the differences in the functional outcome of a shorter (&lt; 45 cm) and longer (\u2a7e 45 cm) ileal segment usage in the reconstruction of the Hautmann ileal neobladder following the radical cystectomy. METHODS: Between July 2013 and September 2015, 121 patients with muscle-invasive bladder cancer underwent radical cystectomy and Hautmann ileal neobladder reconstruction. Patients were divided into two groups, depending on the length of the ileum used for the diversion creation: &lt; 45 cm of the ileum was used in the first group and \u2a7e 45 cm in the second group. Five-year follow-up was performed at 1, 3, 6, and 9 months and 1 and 5 years. The main measured outcomes were functional outcomes and the quality of life. The evaluation included clinical, laboratory, and QLQ-C30 questionnaires. Statistical analysis was performed using descriptive statistics, Mann-Whitney U test, Kolmogorov-Smirnov test, ANOVA, and chi-squared tests. RESULTS: Patients with a smaller neobladder had a better quality of life, and higher global health status scale score. Thirteen early and 21 late complications developed in 10 and 17 patients, respectively. There were significant differences in the need for clean intermittent self-catheterization (CIC) between the two groups: smaller-volume pouch patients had statistically decreased need for CIC in 5 year follow-up compared to larger-volume pouch patients (\u03c72 test = 8.245; df = 1; P= 0.004). Eighteen percent of patients with smaller neobladders had urinary tract infections in 5 years, compared to 35% with larger neobladders (\u03c72 test = 4.447; df = 1; P= 0.034). CONCLUSION: Minimizing the length of the ileal segment needed for Hautmann neobladder reconstruction is feasible and provides better long-term results than larger-volume neobladders.<\/jats:p>","DOI":"10.3233\/thc-230339","type":"journal-article","created":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T11:41:51Z","timestamp":1693309311000},"page":"951-962","source":"Crossref","is-referenced-by-count":1,"title":["Outcome of small versus big capacity Hautmann neobladder reconstruction: A prospective randomized study \u2013 a 5-year follow up"],"prefix":"10.1177","volume":"32","author":[{"given":"Iva Kozul","family":"Salihagic","sequence":"first","affiliation":[{"name":"Department of Urology, University Hospital \u201cSveti Duh\u201d, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adelina","family":"Hrkac","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital \u201cSveti Duh\u201d, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slaven","family":"Ovcaricek","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital \u201cSveti Duh\u201d, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pero","family":"Bokarica","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital \u201cSveti Duh\u201d, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Gilja","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital \u201cSveti Duh\u201d, Zagreb, Croatia"},{"name":"Department of Urology, University Hospital Mostar, Mostar, Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"3","key":"10.3233\/THC-230339_ref1","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1200\/JCO.2001.19.3.666","article-title":"Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1054 patients","volume":"19","author":"Stein","year":"2001","journal-title":"J Clin Oncol."},{"issue":"1","key":"10.3233\/THC-230339_ref2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00345-015-1729-7","article-title":"Open radical cystectomy: Still the gold standard for musle invasive bladder cancer","volume":"34","author":"Kiss","year":"2016","journal-title":"World J Urol."},{"key":"10.3233\/THC-230339_ref3","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1016\/j.juro.2011.02.006","article-title":"25 years of experience with 1000 neobladders: Long-term complications","volume":"185","author":"Hautmann","year":"2011","journal-title":"J Urol."},{"key":"10.3233\/THC-230339_ref4","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/01.ju.0000029010.97686.eb","article-title":"Urinary diversion: Ileal conduit to neobladder","volume":"169","author":"Hautmann","year":"2003","journal-title":"J Urol."},{"key":"10.3233\/THC-230339_ref5","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s00345-006-0061-7","article-title":"Radical cystectomy for invasive bladder cancer: Long-term results of a standard procedure","volume":"24","author":"Stein","year":"2006","journal-title":"World J Urol."},{"key":"10.3233\/THC-230339_ref6","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1111\/j.1464-410X.2010.09283.x","article-title":"Surgery illustrated-surgical atlas. 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