{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T23:58:21Z","timestamp":1786579101648,"version":"build-2736575974"},"reference-count":46,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2024,7,12]]},"abstract":"<jats:p>BACKGROUND: Denture stomatitis, frequently encountered, is generally addressed symptomatically, with limited exploration of preventive approaches involving antifungal medicinal plants. OBJECTIVE: This study assessed the impact of Artemisia sieberi extracts on the candida growth of conventional and digitally processed acrylic materials. METHOD: Thirty acrylic resin discs (3 mm thickness \u00d7 10 mm diameter) were prepared by conventional or CAD\/CAM technology (milling and 3D printing). The resin discs were exposed to simulated brushing, thermocycling, and immersion in Artemisia sieberi extract for 8 hours. The surface roughness of the discs was assessed at baseline and after immersion in Artemisia sieberi extract. Candida growth was quantified through colony-forming units (CFU\/mL). Data was analyzed using SPSS v.22 (\u03b1\u2a7d 0.05). RESULTS: Irrespective of the material type, the post-immersion surface roughness was significantly higher compared to pre-immersion values (p&lt; 0.05). Candida growth was significantly higher in conventional acrylic materials than digitally fabricated acrylics (p&lt; 0.05). At \u00d7 3, Ra and CFU were found to be moderately positive and non-significantly correlated (R= 0.664, p= 0.149). At \u00d7 4, Ra and CFU were found to be weak positive and non-significantly correlated (R= 0.344, p= 0.503). CONCLUSION: Artemisia sieberi extracts had a notable impact on digitally fabricated denture acrylics, reducing candida albicans growth compared to conventional heat-cured acrylic. This suggests a potential role for these extracts in improving denture hygiene and preventing denture stomatitis, particularly in the context of digitally fabricated dentures.<\/jats:p>","DOI":"10.3233\/thc-231767","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T11:59:23Z","timestamp":1710849563000},"page":"2629-2641","source":"Crossref","is-referenced-by-count":3,"title":["Assessing the effect of Artemisia sieberi extracts on surface roughness and candida growth of digitally processed denture acrylic materials"],"prefix":"10.1177","volume":"32","author":[{"given":"Hanan","family":"Alotaibi","sequence":"first","affiliation":[{"name":"Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatimah","family":"Al-Otibi","sequence":"additional","affiliation":[{"name":"Department of Botany and Microbiology, College of Science, King Saud 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