{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:41:51Z","timestamp":1777891311842,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2024,11,8]]},"abstract":"<jats:p>BACKGROUND: The incidence of brain injury is increasing year by year, and it has become one of the major diseases threatening human life in today\u2019s society. From the perspective of the causes of brain injury, it is mainly due to falls from high places, traffic accidents, etc. Severe brain injury patients often lose consciousness. In recent years, the emergence of integrated traditional Chinese and Western medicine has provided a new approach and new ideas for the treatment of craniocerebral trauma. OBJECTIVE: The article systematically and scientifically expounded the role of Xingnaojing injection in the treatment of brain injury by comparing the GCS (Glasgow Coma Scale) score, changes in intracranial pressure, the incidence of complications after brain injury, the transformation from moderate brain injury to severe brain injury, and recovery of consciousness. METHODS: For the problem of gene polymorphism in patients with brain injury, this article discussed the role of APOE2 (Apolipoprotein E2), \u03b53, \u03b54 in brain injury. All patients had a clear history of trauma and received strict nervous system examination and CT scanning when they were admitted to the hospital. After craniocerebral trauma surgery or conservative therapy, patients should take a Xingnaojing injection of 30 ml and a 0.9% sodium chloride injection of 250 ml after admission. After the operation, respiratory tract nursing should be strengthened, and patients who cannot eat should be given nasal feeding, acupuncture, and physiotherapy to prevent bedridden complications. RESULTS: The probability of epilepsy after brain injury was 27%. CONCLUSION: The article would help to evaluate the degree of brain damage and prognosis of patients.<\/jats:p>","DOI":"10.3233\/thc-231864","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T10:31:52Z","timestamp":1728642712000},"page":"4801-4818","source":"Crossref","is-referenced-by-count":0,"title":["Systematic quantitative evaluation of gene polymorphism and therapeutic effect of xingnaojing injection in patients with brain injury"],"prefix":"10.1177","volume":"32","author":[{"given":"Limei","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Critical Care, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxia","family":"Wang","sequence":"additional","affiliation":[{"name":"Infectious Disease Department, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 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