{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:41:45Z","timestamp":1777891305393,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["THC"],"published-print":{"date-parts":[[2024,7,12]]},"abstract":"<jats:p>BACKGROUND: Prosthodontics are often performed to treat patients with malocclusion and dentition defects. However, single prosthodontics cannot properly correct the disharmony of teeth, dental arch and other parts affected by malocclusion, and some patients may have difficulty in recovering the occlusal function due to poor prosthodontics. OBJECTIVE: This study aims to investigate the effect of orthodontics combined with fibre-reinforced composite resin-bonded fixed partial denture (FRC-RBFPD) on anterior dentition defects with minimal vertical intermaxillary space. METHODS: Sixty-two patients with anterior dentition defects with minimal vertical mandibular space admitted to our hospital between March 2021 and May 2023 were enrolled in this study. The participants were divided into the observation group (31 cases) and the control group (31 cases), according to the treatment plan. The control group was treated with traditional therapy, and the observation group was treated with orthodontic combined FRC-RBFPD therapy. Periodontal conditions (periodontal pocket depth [PD], the plaque index [PLI], the sulcus bleeding index [SBI]), levels of inflammatory factors in gingival crevicular fluid (high mobility group box 1 [HMGB1]), myeloid cell triggering receptor-1 (TREM-1), monocyte chemoattractant protein-1 (MCP-1), pain (visual analogue scale [VAS]), the clinical response rate and the incidence of adverse reactions were collected and compared. RESULTS: After 1, 3, 5 and 9 months following treatment, the scores of the PD, PLI, SBI, HMGB1, VAS, TREM-1 and MCP-1 in the observation group were found to be lower than those in the control group (FPD treatment= 352.532, FPLI score treatment= 112.341, FSBI score treatment= 79.479, FVAS score treatment= 96.132, FHMGB1 treatment= 52.532, FTREM-1 score treatment= 64.593, FMCP-1 score treatment= 53.582, and they were all statistically significant P&lt; 0.05). There was a statistically significant difference in the response rate between the two groups (97.77% vs. 80.65%, \u03c72= 4.026, P= 0.045). No statistically significant difference was observed in the incidence of adverse reactions between the two groups (6.45% vs. 16.13%, \u03c72= 1.449, P= 0.229). CONCLUSION: Orthodontics combined with FRC-RBFPD shows an ideal restorative effect on patients with anterior dentition defects and minimal vertical intermaxillary space.<\/jats:p>","DOI":"10.3233\/thc-231889","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T12:00:39Z","timestamp":1710849639000},"page":"2697-2709","source":"Crossref","is-referenced-by-count":0,"title":["Effect of orthodontics combined with fibre-reinforced composite resin-bonded fixed partial denture on anterior dentition defects with minimal vertical intermaxillary space"],"prefix":"10.1177","volume":"32","author":[{"given":"Shi-Lei","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"3","key":"10.3233\/THC-231889_ref3","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.prosdent.2017.01.008","article-title":"Removable partial dentures: The clinical need for innovation","volume":"118","author":"Campbell","year":"2017","journal-title":"J Prosthet Dent."},{"issue":"2","key":"10.3233\/THC-231889_ref4","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/j.2041-1626.2012.00111.x","article-title":"Investigating oral health-related quality of life and self-perceived satisfaction with partial dentures","volume":"3","author":"Abuzar","year":"2012","journal-title":"J Investig Clin Dent."},{"issue":"1","key":"10.3233\/THC-231889_ref5","doi-asserted-by":"publisher","first-page":"102","DOI":"10.5005\/jp-journals-10024-2220","article-title":"Impact of removable partial denture on quality-of-life of sudanese adults in khartoum state","volume":"19","author":"Wahbi","year":"2018","journal-title":"J Contemp Dent Pract."},{"issue":"6","key":"10.3233\/THC-231889_ref6","doi-asserted-by":"publisher","first-page":"449","DOI":"10.3969\/j.issn.1005-4979.2013.06.010","article-title":"Dental implant combined with orthodontic appliances for the prothesis in decreased occlusal-gingival distance patients","volume":"23","author":"Peng","year":"2013","journal-title":"Journal of Oral and Maxillofacial Surgery."},{"issue":"5","key":"10.3233\/THC-231889_ref7","doi-asserted-by":"publisher","first-page":"295","DOI":"10.3969\/j.issn.1003-1634.2023.05.010","article-title":"The clinical performance of invisible orthodontics combined with the implant in treating malocclusion patients with dentition defect","volume":"39","author":"Zhang","year":"2023","journal-title":"Journal of Clinical Stomatology."},{"issue":"10","key":"10.3233\/THC-231889_ref8","first-page":"113","article-title":"Effect of orthodontic combined with prosthodontic therapy in treating patients with malocclusion and dentition defect","volume":"24","author":"Zheng","year":"2020","journal-title":"Journal of Clinical Medicine in Practice."},{"issue":"5","key":"10.3233\/THC-231889_ref9","doi-asserted-by":"publisher","first-page":"872","DOI":"10.4012\/dmj.2012-059","article-title":"Effects of fibers on the color change and stability of resin composites after accelerated aging","volume":"31","author":"Tuncdemir","year":"2012","journal-title":"Dent Mater J."},{"issue":"1","key":"10.3233\/THC-231889_ref10","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/s0109-5641(03)00065-4","article-title":"Flexural properties of fiber reinforced root canal posts","volume":"20","author":"Lassila","year":"2004","journal-title":"Dent Mater."},{"key":"10.3233\/THC-231889_ref13","unstructured":"Long ZX. 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