{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T13:18:11Z","timestamp":1778591891540,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"5-6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VES"],"published-print":{"date-parts":[[2014,12,17]]},"abstract":"<jats:p>Vestibulo-Ocular Reflex (VOR) abnormalities in cerebellar ataxias are a matter of renewed interest. We have previously reported vestibular areflexia in a group of Yemenite-Jews with Spinocerebellar Ataxia Type 3 (SCA3) who had clear bilateral pathological horizontal Head Impulse Test (HIT). The objective of this study was to evaluate the VOR of ten SCA3 patients who have variable bedside HIT responses by recording their eye movements using magnetic search coils and to correlate these results with their clinical and genetic data. Eight out of the ten patients have abnormal horizontal HIT detected by both clinical bedside examination and laboratory tests. Results of bedside HIT testing were significantly correlated with the VOR gain recorded using magnetic search coils. No significant correlations were found between VOR gain and other clinical or genetic data. Our study confirms the presence of defective VOR in SCA3 patients and corroborates the useful of the HIT as a reliable bedside test for diagnosis of VOR deficits.<\/jats:p>","DOI":"10.3233\/ves-140527","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T18:03:43Z","timestamp":1575309823000},"page":"351-355","source":"Crossref","is-referenced-by-count":32,"title":["Impaired vestibulo-ocular reflex (VOR) in spinocerebellar ataxia type 3 (SCA3): Bedside and search coil evaluation"],"prefix":"10.1177","volume":"24","author":[{"given":"Carlos R.","family":"Gordon","sequence":"first","affiliation":[{"name":"Department of Neurology, Meir Medical Center, Kfar Saba and Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ari Z.","family":"Zivotofsky","sequence":"additional","affiliation":[{"name":"Brain Science Program, Bar Ilan University, Ramat Gan, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avi","family":"Caspi","sequence":"additional","affiliation":[{"name":"Department of Electrical and Electronic Engineering, Sami Shamoon College of Engineering, Ashdod, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","container-title":["Journal of Vestibular Research"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/VES-140527","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:22:08Z","timestamp":1777612928000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/VES-140527"}},"subtitle":[],"editor":[{"given":"Marco","family":"Mandal\u00e0","sequence":"additional","affiliation":[{"name":"Otological and Skull Base Surgery Department, S.M. delle Scotte Hospital, Siena, Italy"}],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Stefano","family":"Ramat","sequence":"additional","affiliation":[{"name":"Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy"}],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"David S.","family":"Zee","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,12,17]]},"references-count":0,"journal-issue":{"issue":"5-6"},"URL":"https:\/\/doi.org\/10.3233\/ves-140527","relation":{},"ISSN":["1878-6464","0957-4271"],"issn-type":[{"value":"1878-6464","type":"electronic"},{"value":"0957-4271","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12,17]]}}}