{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:09:41Z","timestamp":1790363381745,"version":"4.1.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"5-6","license":[{"start":{"date-parts":[[2015,6,2]],"date-time":"2015-06-02T00:00:00Z","timestamp":1433203200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vestibular Research"],"published-print":{"date-parts":[[2016,1]]},"abstract":"\n BACKGROUND:<\/jats:title>\n Acute unilateral peripheral vestibular deficit (aUPVD)\npatients have balance deficits that can improve after several weeks.\nDetermining differences in vestibulo-spinal reflex (VSR) influences on\nbalance control and vestibular ocular reflex (VOR) responses with peripheral\nrecovery and central compensation would provide insights into CNS plasticity\nmechanisms. Also, clinically, knowing when balance control is approximately\nnormal again should contribute to decisions about working ability after\naUPVD. Usually VORs are employed for this purpose, despite a lack of\nknowledge about correlations with balance control. Given this background, we\nexamined whether balance and VOR measures improve similarly and are\ncorrelated. Further whether balance improvements are different for stance\nand gait.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n \n 26 patients were examined at onset of aUPVD, and 3, 6 and\n13 weeks later. To measure balance control and thereby assess the\ncontribution of VSR influences during stance and gait, body-worn gyroscopes\nmounted at lumbar 1-3 recorded the angular velocity of the lower trunk in\nthe roll (lateral) and pitch (anterior-posterior) directions. These signals\nwere integrated to yield angle deviations. To measure VOR function, rotating\nchair (ROT) tests were performed with triangular velocity profiles with\naccelerations of 20\u00b0\/s\n 2<\/jats:sup>\n and 5\u00b0\/s\n 2<\/jats:sup>\n , and caloric tests\nwith bithermal (44 and 30\u00b0C) water irrigation of the external auditory\nmeatus. Changes in average balance and VOR measures at the 4 examination\ntime points were modelled with exponential decays. Improvements were assumed\nto plateau when model values were to within 10% of steady state.\n <\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n Balance improvement rates were task and direction\ndependent, ranging from 3-9 weeks post aUPVD, similar to the range of ROT\nVOR improvement rates. Stance balance control improved similarly in the\npitch and roll directions. Both reached steady state at 7.5 weeks. However,\nchanges in visual and proprioceptive influences on stance sway velocities\ncontinued to decrease in favour of vestibular influences for over 10 weeks\nwith the visual influence being correlated with ROT deficit side responses\n(R= 0.475). Spontaneous nystagmus and stance roll velocity were weakly\ncorrelated (R= 0.24). Pitch control during gait tests improved faster than\nroll. Gait speed was slower and only recovered normal velocity at 6-9 weeks.\nPitch velocity when walking eyes closed was correlated (R= 0.38) with ROT\nasymmetry. Other balance and VOR measures were more weakly correlated\n(R< 0.2) even if these had similar improvement rates.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n These results indicate that balance control for stance\nimproves equally fast in the pitch and roll directions. For gait, pitch\ncontrol improves faster than roll. On average, stance and gait tests show\nnormal balance control at 6-9 weeks post aUPVD onset. As few balance\nmeasures are correlated with those of VOR function and then with low (R< 0.5)\ncoefficients, we suggest that VOR tests should not be used to assess\nimprovements in balance control after aUPVD. The lack of strong correlations\nbetween balance and VOR measures included in this study during peripheral\nrecovery and central compensation of aUPVD supports the hypothesis that\nrecovery of balance function after an aUPVD involves different CNS pathways\nand neural plasticity mechanisms.<\/jats:p>\n <\/jats:sec>","DOI":"10.3233\/ves-150561","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T07:30:08Z","timestamp":1454916608000},"page":"219-231","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Recovery times of stance and gait balance control after an acute unilateral peripheral vestibular deficit"],"prefix":"10.1177","volume":"25","author":[{"given":"John H.J.","family":"Allum","sequence":"first","affiliation":[{"name":"Division of Audiology and Neurootology, Department of ORL, University Hospital of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flurin","family":"Honegger","sequence":"additional","affiliation":[{"name":"Division of Audiology and Neurootology, Department of ORL, University Hospital of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,6,2]]},"container-title":["Journal of Vestibular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/VES-150561","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/VES-150561","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:22:15Z","timestamp":1777612935000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/VES-150561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,2]]},"references-count":0,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.3233\/VES-150561"],"URL":"https:\/\/doi.org\/10.3233\/ves-150561","relation":{},"ISSN":["0957-4271","1878-6464"],"issn-type":[{"value":"0957-4271","type":"print"},{"value":"1878-6464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,2]]}}}