{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:18:57Z","timestamp":1777889937084,"version":"3.51.4"},"reference-count":50,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T00:00:00Z","timestamp":1582675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vestibular Research"],"published-print":{"date-parts":[[2020,5,18]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Although vestibular lesions degrade postural control we do not know the relative contributions of the magnitude of the vestibular loss and subjective vestibular symptoms to locomotor adaptation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To study how dizzy symptoms interfere with adaptive locomotor learning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      We examined patients with contrasting peripheral vestibular deficits, vestibular neuritis in the chronic stable phase (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a20) and strongly symptomatic unilateral Meniere\u2019s disease (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a15), compared to age-matched healthy controls (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a15). We measured locomotor adaptive learning using the \u201cbroken escalator\u201d aftereffect, simulated on a motorised moving sled.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Patients with Meniere\u2019s disease had an enhanced \u201cbroken escalator\u201d postural aftereffect. More generally, the size of the locomotor aftereffect was related to how symptomatic patients were across both groups. Contrastingly, the degree of peripheral vestibular loss was not correlated with symptom load or locomotor aftereffect size. During the MOVING trials, both patient groups had larger levels of instability (trunk sway) and reduced adaptation than normal controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Dizziness symptoms influence locomotor adaptation and its subsequent expression through motor aftereffects. Given that the unsteadiness experienced during the \u201cbroken escalator\u201d paradigm is internally driven, the enhanced aftereffect found represents a new type of self-generated postural challenge for vestibular\/unsteady patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/ves-200693","type":"journal-article","created":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T11:19:56Z","timestamp":1582888796000},"page":"81-94","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The \u201cbroken escalator\u201d phenomenon: Vestibular dizziness interferes with locomotor adaptation"],"prefix":"10.1177","volume":"30","author":[{"given":"Mitesh","family":"Patel","sequence":"first","affiliation":[{"name":"Imperial College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed","family":"Roberts","sequence":"additional","affiliation":[{"name":"Imperial College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qadeer","family":"Arshad","sequence":"additional","affiliation":[{"name":"Imperial College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Bunday","sequence":"additional","affiliation":[{"name":"University of Westminster","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John F.","family":"Golding","sequence":"additional","affiliation":[{"name":"Imperial College London","place":["UK"]},{"name":"University of Westminster","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Kaski","sequence":"additional","affiliation":[{"name":"Imperial College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adolfo M.","family":"Bronstein","sequence":"additional","affiliation":[{"name":"Imperial College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,26]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70102-8"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(01)00132-1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2012.00083"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1586\/ern.11.19"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328315a293"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.120121"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.03870.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-006-0446-2"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01214.2007"},{"issue":"3","key":"e_1_3_2_11_2","first-page":"155","article-title":"What is the effect of dizziness on the quality of life for patients with Meniere\u2019s disease?","volume":"126","author":"Cunha F.","year":"2005","unstructured":"CunhaF., SettanniF.A. and GanancaF.F., What is the effect of dizziness on the quality of life for patients with Meniere\u2019s disease? 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