{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:25:26Z","timestamp":1788449126124,"version":"build-2803163510"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vestibular Research"],"published-print":{"date-parts":[[2022,5,2]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Parkinson\u2019s disease (PD) is a common multi-system neurodegenerative disorder with possible vestibular system dysfunction, but prior vestibular function test findings are equivocal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To report and compare vestibulo-ocular reflex (VOR) gain as measured by the video head impulse test (vHIT) in participants with PD, including tremor dominant and postural instability\/gait dysfunction phenotypes, with healthy controls (HC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      Forty participants with PD and 40 age- and gender-matched HC had their vestibular function assessed. Lateral and vertical semicircular canal VOR gains were measured with vHIT. VOR canal gains between PD participants and HC were compared with independent samples\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -tests. Two distinct PD phenotypes were compared to HC using Tukey\u2019s ANOVA. The relationship of VOR gain with PD duration, phenotype, severity and age were investigated using logistic regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>There were no significant differences between groups in vHIT VOR gain for lateral or vertical canals. There was no evidence of an effect of PD severity, phenotype or age on VOR gains in the PD group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>The impulsive angular VOR pathways are not significantly affected by the pathophysiological changes associated with mild to moderate PD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/ves-201626","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T14:08:49Z","timestamp":1623766129000},"page":"261-269","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Vestibular semicircular canal function as detected by video Head Impulse Test (vHIT) is essentially unchanged in people with Parkinson\u2019s disease compared to healthy controls"],"prefix":"10.1177","volume":"32","author":[{"given":"Kim E.","family":"Hawkins","sequence":"first","affiliation":[{"name":"University of Sydney","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Chiarovano","sequence":"additional","affiliation":[{"name":"University of Sydney","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serene S.","family":"Paul","sequence":"additional","affiliation":[{"name":"University of Sydney","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M","family":"Burgess","sequence":"additional","affiliation":[{"name":"University of Sydney","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamish G.","family":"MacDougall","sequence":"additional","affiliation":[{"name":"University of Sydney","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian S.","family":"Curthoys","sequence":"additional","affiliation":[{"name":"University of Sydney","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"303","article-title":"Comparison of electronystagmographic recordings in patients with vertigo and Parkinson\u2019s disease","volume":"50","author":"Dolowitz D.A.","year":"1969","unstructured":"DolowitzD.A., and MagidS.L., Comparison of electronystagmographic recordings in patients with vertigo and Parkinson\u2019s disease, Transactions of the Pacific Coast Oto-Ophthalmological Society Annual Meeting 50(1969), 303\u2013314.","journal-title":"Transactions of the Pacific Coast Oto-Ophthalmological Society Annual Meeting"},{"key":"e_1_3_2_3_2","unstructured":"AllenN.E. SchwartzelA.K. and CanningC.G. Recurrent Falls in Parkinson\u2019s Disease: a systematic review Parkinson\u2019s Disease (2013) 906274."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12168"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-017-5092-3"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63437-5.00003-0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","unstructured":"Garcia-RillE. Arousal and movement disorders in Arousal in Neurological and Psychiatric Diseases E. Garcia-Rill Editor. 2019 Academic Press.","DOI":"10.1016\/B978-0-12-817992-5.00011-8"},{"key":"e_1_3_2_8_2","first-page":"1085","article-title":"Vestibular Functions and Parkinson\u2019s Disease","volume":"9","author":"Smith P.F.","year":"2018","unstructured":"SmithP.F., Vestibular Functions and Parkinson\u2019s Disease, Frontiers in neurology [electronic resource] 9 (2018), 1085.","journal-title":"Frontiers in neurology [electronic resource]"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-72992008000300007"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.32.10.1133"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1988.tb06966.x"},{"issue":"264","key":"e_1_3_2_12_2","first-page":"2018","article-title":"Central Lesions With Selective Semicircular Canal Involvement Mimicking Bilateral Vestibulopathy","volume":"9","author":"Chen L.","unstructured":"ChenL. and HalmagyiG.M., Central Lesions With Selective Semicircular Canal Involvement Mimicking Bilateral Vestibulopathy, Frontiers in Neurology 9(264), 2018.","journal-title":"Frontiers in Neurology"},{"issue":"258","key":"e_1_3_2_13_2","first-page":"2017","article-title":"The Video Head Impulse Test","volume":"8","author":"Halmagyi G.M.","unstructured":"HalmagyiG.M., et al., The Video Head Impulse Test, Frontiers in Neurology 8(258), 2017.","journal-title":"Frontiers in Neurology"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2017.08.021"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2020.01.018"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/09593985.2018.1492055"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphys.2013.12.014"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.07.108"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22340"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23429"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25383"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061488"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181bacf85"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-018-8986-5"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1159\/000362780"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-015-0081-7"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70067-9"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzz033"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.4.699"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aww175"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-151258"},{"key":"e_1_3_2_32_2","first-page":"S276","article-title":"Vestibular rehabilitation in patients with Parkinson\u2019s disease","volume":"29","author":"Zeigelboim B.S.","year":"2014","unstructured":"ZeigelboimB.S., et al., Vestibular rehabilitation in patients with Parkinson\u2019s disease, Movement Disorders 29 (2014), S276\u2013S276.","journal-title":"Movement Disorders"}],"container-title":["Journal of Vestibular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/VES-201626","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/VES-201626","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/VES-201626","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:26:21Z","timestamp":1777613181000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/VES-201626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,11]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5,2]]}},"alternative-id":["10.3233\/VES-201626"],"URL":"https:\/\/doi.org\/10.3233\/ves-201626","relation":{},"ISSN":["0957-4271","1878-6464"],"issn-type":[{"value":"0957-4271","type":"print"},{"value":"1878-6464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,11]]}}}