{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T20:41:12Z","timestamp":1788640872331,"version":"build-2803163510"},"reference-count":51,"publisher":"SAGE Publications","issue":"2-3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VES"],"published-print":{"date-parts":[[2024,5,9]]},"abstract":"<jats:p>BACKGROUND: Our sense of direction (SOD) ability relies on the sensory integration of both visual information and self-motion cues from the proprioceptive and vestibular systems. Here, we assess how dysfunction of the vestibular system impacts perceived SOD in varying vestibular disorders, and secondly, we explore the effects of dizziness, migraine and psychological symptoms on SOD ability in patient and control groups. METHODS: 87 patients with vestibular disorder and 69 control subjects were assessed with validated symptom and SOD questionnaires (Santa Barbara Sense of Direction scale and the Object Perspective test). RESULTS: While patients with vestibular disorders performed significantly worse than controls at the group level, only central and functional disorders (vestibular migraine and persistent postural perceptual dizziness), not peripheral disorders (benign-paroxysmal positional vertigo, bilateral vestibular failure and Meniere\u2019s disease) showed significant differences compared to controls on the level of individual vestibular groups. Additionally, orientational abilities associated strongly with spatial anxiety and showed clear separation from general dizziness and psychological factors in both patient and control groups. CONCLUSIONS: SOD appears to be less affected by peripheral vestibular dysfunction than by functional and\/or central diagnoses, indicating that higher level disruptions to central vestibular processing networks may impact SOD more than reductions in sensory peripheral inputs. Additionally, spatial anxiety is highly associated with orientational abilities in both patients and control subjects.<\/jats:p>","DOI":"10.3233\/ves-230082","type":"journal-article","created":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T13:05:56Z","timestamp":1710248756000},"page":"113-123","source":"Crossref","is-referenced-by-count":5,"title":["Sense of direction in vestibular disorders"],"prefix":"10.1177","volume":"34","author":[{"given":"Alexander I.G.","family":"Moore","sequence":"first","affiliation":[{"name":"Department of Brain Sciences, Neuro-otology Unit, Imperial College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Golding","sequence":"additional","affiliation":[{"name":"Department of Brain Sciences, Neuro-otology Unit, Imperial College London, London, UK"},{"name":"Department of Psychology, University of Westminster, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Alenova","sequence":"additional","affiliation":[{"name":"Department of Brain Sciences, Neuro-otology Unit, Imperial College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Castro","sequence":"additional","affiliation":[{"name":"Department of Brain Sciences, Neuro-otology Unit, Imperial College London, London, UK"},{"name":"Escuela de Fonoaudiologia, Facultad de Medicina Clinica Alemana, Universidad del Desarrollo, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo M.","family":"Bronstein","sequence":"additional","affiliation":[{"name":"Department of Brain Sciences, Neuro-otology Unit, Imperial College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/VES-230082_ref1","doi-asserted-by":"crossref","first-page":"107409","DOI":"10.1016\/j.clineuro.2022.107409","article-title":"Vestibular migraine and persistent postural perceptual dizziness: Handicap, emotional comorbidities, quality of life and personality traits","volume":"221","author":"Ak","year":"2022","journal-title":"Clin Neurol Neurosurg"},{"key":"10.3233\/VES-230082_ref2","doi-asserted-by":"crossref","unstructured":"Alvarez-Vargas D. , Abad C. , Pruden S.M. , Spatial anxiety mediates the sex difference in adult mental rotation test performance, Cogn Res Princ Implic (2020) 5, 31-020\u201300231\u20138","DOI":"10.1186\/s41235-020-00231-8"},{"key":"10.3233\/VES-230082_ref3","doi-asserted-by":"crossref","first-page":"120579","DOI":"10.1016\/j.jns.2023.120579","article-title":"Factors influencing clinical outcome in vestibular neuritis - A focussed review and reanalysis of prospective data","volume":"446","author":"Arshad","year":"2023","journal-title":"J Neurol Sci"},{"key":"10.3233\/VES-230082_ref4","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1586\/ern.11.19","article-title":"Neurologic bases for comorbidity of balance disorders, anxiety disorders and migraine: neurotherapeutic implications","volume":"11","author":"Balaban","year":"2011","journal-title":"Expert Rev Neurother"},{"key":"10.3233\/VES-230082_ref5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1055\/s-0039-3402735","article-title":"Vestibular Migraine I: Mechanisms, Diagnosis, and Clinical Features","volume":"40","author":"Baloh","year":"2020","journal-title":"Semin Neurol"},{"key":"10.3233\/VES-230082_ref6","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.jalz.2013.11.006","article-title":"Development and validation of a brief dementia screening indicator for primary care","volume":"10","author":"Barnes","year":"2014","journal-title":"Alzheimers Dement"},{"key":"10.3233\/VES-230082_ref7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s00415-009-0038-8","article-title":"Psychiatric morbidity and comorbidity in different vestibular vertigo syndromes. 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