{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:44:24Z","timestamp":1777891464247,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T00:00:00Z","timestamp":1541635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of X-Ray Science and Technology"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Improved visualization of lung cancer-associated vessels is vital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To evaluate the efficacy of 3-D quantitative CT in lung cancer-associated pulmonary vessel assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      Vascular CT changes were assessed visually and using FACT-Digital lung TM software (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u200a=\u200a162 patients, 178 controls). The total number of pulmonary vessels (TNV) and mean lumen area of pulmonary vessels (MAV) vertical to cross-sections of fifth\/sixth-generation bronchioles were measured.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Visual investigation revealed fewer ipsilateral pulmonary vascular abnormalities in lung cancer (151\/162) than did quantitative CT (162\/162), and required more time (3.2\u00b11.5 vs. 2.5\u00b11.3\u200amin) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u200a&lt;\u200a0.05). CT measurements revealed that the TNV vertical to the fifth-generation bronchial cross-section of the ipsilateral, contralateral, and control groups was 14.58\u00b14.75, 9.58\u00b13.74, and 10.22\u00b14.07 and the MAV in these groups was 99.70\u00b126.20, 58.76\u00b129.29, and 57.76\u00b118.32, respectively. The TNV vertical to the sixth-generation bronchial cross-section of the ipsilateral, contralateral, and control groups was 16.64\u00b15.14, 11.59\u00b14.06, and 11.75\u00b14.16 and the MAV was 110.22\u00b131.47, 67.62\u00b130.41, and 60.24\u00b116.18, respectively. The TNV and MAV in ipsilateral lung cancer tissues exceeded those in the contralateral side and control group tissues (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u200a&lt;\u200a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Automated 3-D quantitative CT could successfully characterize pulmonary vessels and their lung cancer-associated changes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/xst-180429","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T17:23:10Z","timestamp":1541784190000},"page":"149-160","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Morphological analysis of blood vessels near lung tumors using 3-D quantitative 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