{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:39:30Z","timestamp":1780965570447,"version":"3.54.1"},"reference-count":40,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,6,5]],"date-time":"2022-06-05T00:00:00Z","timestamp":1654387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of X-Ray Science and Technology"],"published-print":{"date-parts":[[2022,9,30]]},"abstract":"<jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>\n                      To investigate\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG PET\/CT findings of tuberculous lymphadenitis and analyze the causes of misdiagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>METHOD:<\/jats:title>\n                    <jats:p>Between 2013 and 2021, a retrospective review was conducted on 22 patients at Jiangxi Provincial People\u2019s Hospital Affiliated with Nanchang University who had lymph node tuberculosis confirmed by histology or clinical investigation. Subjective judgment and quantitative analysis were adopted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Out of 22 patients, 14 are male and 8 are female. The average age was 55.5 years (55.5\u00b112.4). The most common site of lymph node tuberculosis (LNTB) is the mediastinum (41.5%), followed by the neck (24.4%) and the abdominal cavity (21.9%). Half of the patients have more than one site affected. More than half of LNTB patients (54.5%) are concurrent with other types of TB, especially PTB. Among the 41 biggest affected lymph nodes, the average maximum diameter, minimum diameter, SUVmax and the lesion SUVmax\/SUVmean liver ratio are 22.04\u00b18.39, 16.93\u00b16.75, 9.72\u00b15.04 and 6.72\u00b13.60, respectively. There is a poor correlation coefficient of 0.236 between the FDG uptake and the size of the biggest affected lymph node. Patients who are concurrent with no other TB have the significantly higher FDG uptake than patients who are concurrent with other TB (12.42 vs 8.02) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u200a=\u200a0.005). Among these cases, 6 cases (27.3%) are accurately diagnosed with LNTB, all of which have pulmonary tuberculosis as a complication. However, 16 cases (72.7%) are misdiagnosed as lymphoma (50%), sarcoidosis (13.6%), and lymph node metastasis (9%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec specific-use=\"heading-level-1\">\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>\n                      This study demonstrates that\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG PET\/CT is very useful in detecting LNTB because tuberculous granulomas show significant levels of glucose uptake. It proves to be an effective method for revealing lesion extent and discovering additional lesions that morphological imaging is missed. However,\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG PET\/CT is not able to reliably distinguish LNTB from lymphoma, sarcoidosis, and metastatic lymph nodes. Nonetheless,\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG PET\/CT allows for the selection of the most optimal biopsy location, and thus has potential to detect early treatment response and distinguish between active and inactive lesions.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/xst-221195","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T12:47:12Z","timestamp":1654606032000},"page":"941-951","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Analysis of misdiagnosis and\n                    <sup>18<\/sup>\n                    F-FDG PET\/CT findings of lymph node tuberculosis"],"prefix":"10.1177","volume":"30","author":[{"given":"Fengxiang","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Jiangxi Provincial People\u2019s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zizhen","family":"Huang","sequence":"additional","affiliation":[{"name":"Sterilization and Supply Center","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Jiangxi Provincial People\u2019s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhehuang","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Jiangxi Provincial People\u2019s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanling","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Jiangxi Provincial People\u2019s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Jiangxi Provincial People\u2019s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juhong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Jiangxi Provincial People\u2019s Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,5]]},"reference":[{"key":"e_1_3_1_2_2","unstructured":"World Health Organization. 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