{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:17:28Z","timestamp":1777889848555,"version":"3.51.4"},"reference-count":66,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T00:00:00Z","timestamp":1498262400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Main Group Chemistry"],"published-print":{"date-parts":[[2017,6,24]]},"abstract":"<jats:p>\n                    In the present paper, the essential oil and the volatiles emitted in vivo by leaves of A.\u00a0herba alba, which grows wild in center of Tunisia, were analyzed by GC-MS and SPME, respectively. The essential oil was characterized by the predominance of oxygenated monoterpenes (93.3%) with \u03b1-thujone as the major compound (45.5%) followed by \u03b2-thujone (11.4%), trans-sabinyl acetate (10.1%) and 1,8-cineole (7.4%). The SPME analyses showed that oxygenated monoterpenes were the most representative compounds (64.9%). The major ones were \u03b1-thujone (37.9%), germacrene D (16.5%), 1,8-cineole (8.4%) followed by \u03b2-thujone (7.8%). Moreover, different activities (antioxidant, antibacterial, allelopathic and insecticidal) of the leaf essential oil were investigated. The antioxidant activity was ascertained by evaluating its inhibitory effect against DPPH and ABTS. The results showed that the essential oil had a strong activity and it was more effective against the DPPH radical (IC\n                    <jats:sub>50<\/jats:sub>\n                    \u200a=\u200a6 \u03bcg\/mL) than the ABTS radical (IC\n                    <jats:sub>50<\/jats:sub>\n                    \u200a=\u200a40 \u03bcg\/mL). In antibacterial screening, it inhibited the growth of all bacteria tested except Salmonella anatum and Salmonella salamae which were resistant to this oil type. Staphylococcus aureus and Vibrio cholera were found to be extremely sensitive with the lowest MIC value (0.007\u200amg\/mL). In addition, allelopathic activity was evaluated against Lactuca sativa and Raphanus sativus. Data showed that, with essential oil, seed germination was completely inhibited for both of them, suggesting a potent allelopathic potential for the evaluated oil. Insecticidal activity was investigated against Culex pipiens larvae and a weak activity (LC\n                    <jats:sub>50<\/jats:sub>\n                    241.1\u200appm) for this A. herba alba essential oil.\n                  <\/jats:p>","DOI":"10.3233\/mgc-170229","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T10:50:16Z","timestamp":1498560616000},"page":"95-109","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Phytochemical identification of volatile fraction, essential oil and screening of\u00a0antioxidant, antibacterial, allelopathic and\u00a0insecticidal potential from\n                    <i>Artemisia herba-alba<\/i>\n                    leaves"],"prefix":"10.1177","volume":"16","author":[{"given":"Sana","family":"Bellili","sequence":"first","affiliation":[{"name":"University Manouba, ISBST, BVBGR-LR11ES31, Biotechpole Sidi Thabet, Ariana, Tunisia"},{"name":"Faculty of Sciences of Bizerte, Jarzouna \u2013 Bizerte, University of Carthage, Tunisia"}]},{"given":"Sabrine","family":"Jazi","sequence":"additional","affiliation":[{"name":"University Manouba, ISBST, BVBGR-LR11ES31, Biotechpole Sidi Thabet, Ariana, Tunisia"},{"name":"Faculty of Sciences of Bizerte, Jarzouna \u2013 Bizerte, University of Carthage, Tunisia"}]},{"given":"Mohamed Yahya","family":"Hrira","sequence":"additional","affiliation":[{"name":"UR 07\/06, Laboratoire de Biochimie, Facult\u00e9 de Pharmacie de Monastir, Universit\u00e9 de Monastir, Monastir, Tunisie"}]},{"given":"Ali","family":"Lamari","sequence":"additional","affiliation":[{"name":"Laboratoire de G\u00e9n\u00e9tique, Facult\u00e9 de M\u00e9decine de Monastir, Universit\u00e9 de Monastir, Monastir, Tunisie"}]},{"given":"Wissal","family":"Dhifi","sequence":"additional","affiliation":[{"name":"UR Ecophysiologie Environnementale et Proc\u00e9d\u00e9s Agroalimentaires, Institut Sup\u00e9rieur de Biotechnologie de Sidi Thabet, BiotechPole de Sidi Thabet, Universit\u00e9 de la Manouba, Tunisie"}]},{"given":"Mohamed Fethi","family":"Diouani","sequence":"additional","affiliation":[{"name":"LR11-IPT03 Epid\u00e9miologie et de Microbiologie V\u00e9t\u00e9rinaire, Institut Pasteur de Tunis 13 Place Pasteur, Tunis Belv\u00e9d\u00e8re, Tunisie"}]},{"given":"Maria Eduarda","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica e Bioqu\u00edmica Faculdade de Ci\u00eancias da Universidade de Lisboa Campo Grande, Lisboa, Portugal"}]},{"given":"Pier Luigi","family":"Cioni","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Bioorganic Chemistry and Biopharmaceutics University of Pisa, Pisa, Italy"}]},{"given":"Guido","family":"Flamini","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Bioorganic Chemistry and Biopharmaceutics University of Pisa, Pisa, Italy"}]},{"given":"Ameur","family":"Cherif","sequence":"additional","affiliation":[{"name":"University Manouba, ISBST, BVBGR-LR11ES31, Biotechpole Sidi Thabet, Ariana, Tunisia"}]},{"given":"Wissem","family":"Mnif","sequence":"additional","affiliation":[{"name":"University Manouba, ISBST, BVBGR-LR11ES31, Biotechpole Sidi Thabet, Ariana, Tunisia"},{"name":"Faculty of Sciences and Arts in Balgarn, Balgarn- Sabt Al Alaya, Bisha University, Saudi Arabia"}]}],"member":"179","published-online":{"date-parts":[[2017,6,24]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/617459"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1016\/S0308-8146(03)00267-X"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1021\/jf021074s"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1021\/jf0352881"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-012-3251-9"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.4314\/ijbcs.v8i4.53"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2004.07.010"},{"key":"ref008","unstructured":"JuddW.S., CampbellC.S., KelloggE.A., StevensP.F. and DonoghueM.J., Plant systematics: A phylogenetic approach (2nd ed.) Sinauer Associates Inc. (2002), USA."},{"key":"ref009","first-page":"1","volume":"4","author":"Abou El-Hamd H.M.","year":"2010","journal-title":"Rec Nat Prod"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2008.02.014"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2008.09.101"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2010.11.003"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytol.2011.07.003"},{"key":"ref014","first-page":"1","volume":"4","author":"Mohamed A.H.","year":"2010","journal-title":"Rec Nat Prod"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1016\/0378-8741(95)01302-4"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2006.09.011"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.01.031"},{"key":"ref018","first-page":"165","volume":"58","author":"Kim T.H.","year":"2004","journal-title":"Nat Med"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1080\/10412905.2008.9700061"},{"key":"ref020","first-page":"29","volume":"2","author":"Akrout A.","year":"2010","journal-title":"Recent Res Sci Technol"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1016\/j.crci.2009.09.008"},{"key":"ref022","first-page":"346","volume":"17","author":"Clevenger J.F.","year":"1928","journal-title":"J Am Pharm Assoc"},{"key":"ref023","unstructured":"AdamsR.P., Identification of essential oil components by gas chromatography\/quadrupole mass spectrometry, 2nd Ed.; Allured Publ. Corp.: Carol Stream, IL. (2001), USA."},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)81487-4"},{"key":"ref025","unstructured":"JenningsW. and ShibamotaT., Quantitative Analysis of Flavor and Fragrance Volatiles by Glass Capillary Chromatography. Academic Press, (1980), New York."},{"key":"ref026","unstructured":"MassadaY., Analysis of Essential Oil by Gas Chromatography and Spectrometry. John Wiley & Sons, (1976), New York."},{"key":"ref027","unstructured":"StenhagenE., AbrahamssonS. and McLaffertyF.W., Registry of mass spectral data. J. Wiley & Sons. (1974), New York."},{"key":"ref028","unstructured":"SwigarA.A. and SilvesteinR.M., Monoterpenes. Aldrich Chemical Company, (1981), Milwaukee."},{"key":"ref029","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2006.08.014"},{"key":"ref030","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2007.02.010"},{"key":"ref031","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-6915(01)00103-X"},{"key":"ref032","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-34923"},{"key":"ref033","unstructured":"RaymandM., PratoG. and RatsiraD., Probit analysis of mortality assays displaying quantal response. Version 3.3, licence CNRS-UMII L93019. Paraxeme, 34680 St. George d\u2019Orques, (1993), France."},{"key":"ref034","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2007.02.053"},{"key":"ref035","first-page":"528","volume":"23","author":"Ouyahya A.","year":"1990","journal-title":"Food Sci Technol"},{"key":"ref036","first-page":"147","volume-title":"Food Flavors: Generation, Analysis androcess Influence","author":"Vernin G.","year":"1995"},{"key":"ref037","first-page":"289","volume":"62","author":"Akrout A.","year":"2004","journal-title":"Cahiers Options Mediterran\u00e9ennes"},{"key":"ref038","doi-asserted-by":"publisher","DOI":"10.1080\/10412905.2006.9699096"},{"key":"ref039","doi-asserted-by":"publisher","DOI":"10.1016\/j.bse.2003.09.002"},{"key":"ref040","first-page":"2413","volume":"10","author":"Sharifian M.","year":"2011","journal-title":"Electron J Environ Agric Food Chem"},{"key":"ref041","doi-asserted-by":"publisher","DOI":"10.5897\/AJB10.2491"},{"key":"ref042","first-page":"1273","volume":"4","author":"Khennouf S.","year":"2010","journal-title":"J Med Plant Res"},{"key":"ref043","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2012.04.042"},{"key":"ref044","author":"Bourgou S.","year":"2015","journal-title":"Int J Food Prop"},{"key":"ref045","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2008.10.010"},{"key":"ref046","doi-asserted-by":"publisher","DOI":"10.1016\/S0308-8146(01)00198-4"},{"key":"ref047","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2005.03.006"},{"key":"ref048","doi-asserted-by":"publisher","DOI":"10.1016\/S0023-6438(03)00088-4"},{"key":"ref049","doi-asserted-by":"publisher","DOI":"10.1046\/j.1472-765x.2000.00731.x"},{"key":"ref050","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(97)00070-6"},{"key":"ref051","first-page":"189","volume":"6","author":"Mothana R.A.","year":"2012","journal-title":"Rec Nat Prod"},{"key":"ref052","first-page":"1563","volume":"7","author":"Bouhdid S.","year":"2008","journal-title":"Afr J Biotechnol"},{"key":"ref053","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.09.044"},{"key":"ref054","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.1998.00338.x"},{"key":"ref055","doi-asserted-by":"publisher","DOI":"10.1021\/jf950540t"},{"key":"ref056","doi-asserted-by":"publisher","DOI":"10.1021\/jf0105034"},{"key":"ref057","doi-asserted-by":"publisher","DOI":"10.1021\/jf060752y"},{"key":"ref058","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-003-1054-z"},{"key":"ref059","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009848215019"},{"key":"ref060","doi-asserted-by":"publisher","DOI":"10.1016\/S0305-1978(02)00202-8"},{"key":"ref061","doi-asserted-by":"publisher","DOI":"10.1016\/j.bse.2010.12.022"},{"key":"ref062","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2011.10.019"},{"key":"ref063","doi-asserted-by":"publisher","DOI":"10.1078\/1433-8319-00011"},{"key":"ref064","first-page":"33","volume":"6","author":"El-Hawary S.S.","year":"2013","journal-title":"A Juss IJARNP"},{"key":"ref065","doi-asserted-by":"publisher","DOI":"10.1002\/ps.486"},{"key":"ref066","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-010-1865-3"}],"container-title":["Main Group Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/MGC-170229","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/MGC-170229","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/MGC-170229","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:21:51Z","timestamp":1777612911000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/MGC-170229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,24]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,6,24]]}},"alternative-id":["10.3233\/MGC-170229"],"URL":"https:\/\/doi.org\/10.3233\/mgc-170229","relation":{},"ISSN":["1024-1221","1745-1167"],"issn-type":[{"value":"1024-1221","type":"print"},{"value":"1745-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,24]]}}}