{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:35:16Z","timestamp":1789914916354,"version":"4.0.1"},"reference-count":38,"publisher":"Deutscher Arzte-Verlag GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.3238\/arztebl.2018.0628","type":"journal-article","created":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T09:50:45Z","timestamp":1536918645000},"source":"Crossref","is-referenced-by-count":10,"title":["Breast Implant-Associated Lymphoma"],"prefix":"10.3238","author":[{"given":"Julian","family":"Kricheldorff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva Maria","family":"Fallenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Solbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Gerber-Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Rancs\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"von Fritschen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11437","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"key":"10.3238\/arztebl.2018.0628_ref1","unstructured":"FDA: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). www.fda.gov\/medicaldevices\/productsandmedicalprocedures\/implantsandprosthetics\/breastimplants\/ucm239995.htm (last accessed on 2 July 2017)."},{"key":"10.3238\/arztebl.2018.0628_ref2","doi-asserted-by":"crossref","unstructured":"Keech JA Jr, Creech BJ: Anaplastic T-cell lymphoma in proximity to a saline-filled breast implant. Plast Reconstr Surg 1997; 100: 554\u20135","DOI":"10.1097\/00006534-199708000-00065"},{"key":"10.3238\/arztebl.2018.0628_ref3","unstructured":"FDA: Medical device reports of breast implant-associated anaplastic large cell lymphoma. www.fda.gov\/MedicalDevices\/ProductsandMedicalProcedures\/ImplantsandProsthetics\/BreastImplants\/ucm481899.htm (last accessed on 8 April 2018)."},{"key":"10.3238\/arztebl.2018.0628_ref4","doi-asserted-by":"crossref","unstructured":"Clemens MW, Brody GS, Mahabir RC, Miranda RN: How to diagnose and treat breast implant-associated anaplastic large cell lymphoma. Plast Reconstr Surg 2018; 14: 586e\u201399e.","DOI":"10.1097\/PRS.0000000000004262"},{"key":"10.3238\/arztebl.2018.0628_ref5","doi-asserted-by":"crossref","unstructured":"Clemens MW, Horwitz SM: NCCN consensus guidelines for the diagnosis and management of breast implant-associated anaplastical large cell lymphoma. Aesthet Surg J 2017; 37: 285\u20139","DOI":"10.1093\/asj\/sjw259"},{"key":"10.3238\/arztebl.2018.0628_ref6","doi-asserted-by":"crossref","unstructured":"Kim B, Predmore ZS, Mattke S, et al.: Breast-implant-associated anaplastic large cell lymphoma: updated results from a structured expert consultation process. Plast Reconstr Surg Glob Open 2015; 3: e296","DOI":"10.1097\/GOX.0000000000000268"},{"key":"10.3238\/arztebl.2018.0628_ref7","unstructured":"NCCN: Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non-Hodgkin\u2019s Lymphomas; January 25, 2012. www.nccn.org\/professionals\/physician_gls\/f_guidelines.asp#nhl (last accessed on 15 December 2017)."},{"key":"10.3238\/arztebl.2018.0628_ref8","doi-asserted-by":"crossref","unstructured":"Aladily TN, Medeiros LJ, Amin MB, et al.: Anaplastic large cell lymphoma associated with breast implants: a report of 13 cases. Am J Durg Pathol 2012; 36: 1000","DOI":"10.1097\/PAS.0b013e31825749b1"},{"key":"10.3238\/arztebl.2018.0628_ref9","doi-asserted-by":"crossref","unstructured":"Clemens MW, Medeiros LJ, Butler CE, et al.: Complete surgical excision is essential for the management of patients with breast implant-associated anaplastic large-cell lymphoma. J Clin Oncol 2016; 34: 160\u20138","DOI":"10.1200\/JCO.2015.63.3412"},{"key":"10.3238\/arztebl.2018.0628_ref10","doi-asserted-by":"crossref","unstructured":"Thompson PA, Lade S, Webster H, et al.: Effusion-associated anaplastic large cell lymphoma of the breast: time for it to be defined as a distinct-pathological entity. Haematologica 2010; 95: 1977","DOI":"10.3324\/haematol.2010.026237"},{"key":"10.3238\/arztebl.2018.0628_ref11","unstructured":"NIH: Adult non-hodgkin lymphoma treatment. (PDQ)\u2013Patient Version. www.cancer.gov\/types\/lymphoma\/patient\/adult-nhl-treatment-pdq (last accessed on 1 March 2018)."},{"key":"10.3238\/arztebl.2018.0628_ref12","doi-asserted-by":"crossref","unstructured":"Swerdlow SH, Campo E, Pileri SA, et al.: The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016; 127: 2375\u201390","DOI":"10.1182\/blood-2016-01-643569"},{"key":"10.3238\/arztebl.2018.0628_ref13","doi-asserted-by":"crossref","unstructured":"Kim B, Roth C, Chung KC, et al.: Anaplastic large cell lymphoma and breast implants: a systematic review. Plast Reconstr Surg 2011; 127: 2141","DOI":"10.1097\/PRS.0b013e3182172418"},{"key":"10.3238\/arztebl.2018.0628_ref14","unstructured":"European Comission Scientific Committee on Health Environmental and Emerging Risks SCHEER: Scientific advice on the state of scientific knowledge regarding a possible connection between breast implants and anaplastic large cell lymphoma. 2017. https:\/\/ec.europa.eu\/health\/scientific_committees\/consultations\/public_consultations\/scheer_consultation_06_en (last accessed on 8 May 2018)."},{"key":"10.3238\/arztebl.2018.0628_ref15","unstructured":"George EV, Pharm J, Houston C, et al.: Breast implant-associated ALK-negative anaplastic large cell lymphoma: a case report and discussion of possible pathogenesis. Int J Clin Exp Pathol 2013; 6: 1631"},{"key":"10.3238\/arztebl.2018.0628_ref16","doi-asserted-by":"crossref","unstructured":"Bizjak M, Selmi C, Praprotnik S, et al.: Silicone implants and lymphoma: the role of inflammation. J Autoimmun 2015; 65: 64\u201373","DOI":"10.1016\/j.jaut.2015.08.009"},{"key":"10.3238\/arztebl.2018.0628_ref17","doi-asserted-by":"crossref","unstructured":"Orciani M, Sorgentoni G, Torresetti M, et al.: MSCs and inflammation: new insights into the potential association between ALCL and breast implants. Breast Cancer Res Treat 2016; 156: 65\u201372","DOI":"10.1007\/s10549-016-3745-8"},{"key":"10.3238\/arztebl.2018.0628_ref18","doi-asserted-by":"crossref","unstructured":"Barnsley GP, Sigurdson LJ, Barnsley SE: Textured surface breast implants in the prevention of capsular contracture among breast augmentation patients: a meta-analysis of randomized controlled trials. Plast Reconstr Surg 2006; 117: 2182\u201390","DOI":"10.1097\/01.prs.0000218184.47372.d5"},{"key":"10.3238\/arztebl.2018.0628_ref19","doi-asserted-by":"crossref","unstructured":"Brody GS, Deapen D, Taylor CR, et al.: Anaplastic large cell lymphoma occurring in women with breast implants. Analysis of 173 cases. Plast Reconstr Surg 2015; 135: 695\u2013705","DOI":"10.1097\/PRS.0000000000001033"},{"key":"10.3238\/arztebl.2018.0628_ref20","doi-asserted-by":"crossref","unstructured":"Hu H, Johani K, Almatroudi A, et al.: Bacterial biofilm infection detected in breast implant-associated anaplastic large-cell lymphoma. Plast Reconstr Surg 2016; 137: 1659\u201369","DOI":"10.1097\/PRS.0000000000002010"},{"key":"10.3238\/arztebl.2018.0628_ref21","doi-asserted-by":"crossref","unstructured":"Adams WP Jr: Discussion: Bacterial biofilm infection detected in breast implant-associated anaplastic large-cell lymphoma. Plast Reconstr Surg 2016; 137: 1670\u20132","DOI":"10.1097\/PRS.0000000000002170"},{"key":"10.3238\/arztebl.2018.0628_ref22","doi-asserted-by":"crossref","unstructured":"Lipworth L, Tarone RE, McLaughlin JK: Breast implants and lymphoma risk: a review of the epidemiologic evidence through 2008. Plast Reconstr Surg 2009; 123: 790\u20133","DOI":"10.1097\/PRS.0b013e318199edeb"},{"key":"10.3238\/arztebl.2018.0628_ref23","doi-asserted-by":"crossref","unstructured":"Srinivasa DR, Miranda RN, Kaura A, et al.: Global Adverse Event Reports of Breast Implant-Associated ALCL: an international review of 40 government authority databases. Plast Reconstr Surg 2017; 139: 1029\u201339","DOI":"10.1097\/PRS.0000000000003233"},{"key":"10.3238\/arztebl.2018.0628_ref24","doi-asserted-by":"crossref","unstructured":"de Jong D, Vasel WL, de Boer JP, et al.: Anaplastic large-cell lymphoma in women with breast implants. JAMA 2008; 300: 2030\u20135","DOI":"10.1001\/jama.2008.585"},{"key":"10.3238\/arztebl.2018.0628_ref25","doi-asserted-by":"crossref","unstructured":"de Boer M, van Leeuwen FE, Hauptmann M, et al.: Breast implants and the risk of anaplastic large-cell lymphoma in the breast. JAMA Oncol 2018; 4: 335\u201341","DOI":"10.1001\/jamaoncol.2017.4510"},{"key":"10.3238\/arztebl.2018.0628_ref26","doi-asserted-by":"crossref","unstructured":"Doren EL, Miranda RN, Selber JC, et al.: U.S. epidemiology of breast implant-associated anaplastic large-cell lymphoma. Plast Reconstr Surg 2017; 139: 1042\u201350","DOI":"10.1097\/PRS.0000000000003282"},{"key":"10.3238\/arztebl.2018.0628_ref27","doi-asserted-by":"crossref","unstructured":"Loch-Wilkinson A, Beath KJ, Knight RJW, et al.: Breast implant-associated anaplastic large cell lymphoma in Australia and New Zealand: high-surface-area textured implants are associated with increased risk. Plast Reconstr Surg 2017; 140: 645\u201354","DOI":"10.1097\/PRS.0000000000003654"},{"key":"10.3238\/arztebl.2018.0628_ref28","unstructured":"Clemens MW, Miranda RN: Coming of age: breast implant-associated anaplastic large cell lymphoma after 18 years of investigation. Clin Plast Surg 2015; 42: 605\u201313"},{"key":"10.3238\/arztebl.2018.0628_ref29","doi-asserted-by":"crossref","unstructured":"Palraj B, Paturi A, Stone RG, et al.: Soft tissue anaplastic large T-cell lymphoma associated with a metallic orthopedic implant: case report and review of current literature. J Foot Ankle Surg 2010; 49: 561","DOI":"10.1053\/j.jfas.2010.08.009"},{"key":"10.3238\/arztebl.2018.0628_ref30","unstructured":"Coleman MP: Cancer risk from orthopedic prostheses. Ann Clin Lab Sci 1996; 26: 139\u201346"},{"key":"10.3238\/arztebl.2018.0628_ref31","doi-asserted-by":"crossref","unstructured":"Yoon HJ, Choe JY, Jeon YK: Mucosal CD30-positive T-cell lymphoproliferative disorder arising in the oral cavity following dental implants: report of the first case. Int J Surg Pathol 2015; 23: 656\u201361","DOI":"10.1177\/1066896915599059"},{"key":"10.3238\/arztebl.2018.0628_ref32","doi-asserted-by":"crossref","unstructured":"Taylor CR, Siddiqi IN, Brody GS: Anaplastic large cell lymphoma occurring in association with breast implants: review of pathologic and immunohistochemical features in 103 cases. Appl Immunohistochem Mol Morphol 2013; 21: 13\u201320","DOI":"10.1097\/PAI.0b013e318266476c"},{"key":"10.3238\/arztebl.2018.0628_ref33","doi-asserted-by":"crossref","unstructured":"Adrada BE, Miranda RN, Rauch GM, et al.: Breast-implant associated anaplastic large cell lymphoma: sensitivity, specifitiy, and findings of imaging studies in 44 patients. Breast Cancer Res Treat 2014; 147: 1\u201314","DOI":"10.1007\/s10549-014-3034-3"},{"key":"10.3238\/arztebl.2018.0628_ref34","doi-asserted-by":"crossref","unstructured":"Bautista-Quach MA, Nademanee A, Weisenburger DD, Chen W, Kim YS: Implant-associated primary anaplastic large-cell lymphoma with simultaneous involvement of bilateral breast capsules. Clin Breast Cancer 2013; 13: 492\u20135","DOI":"10.1016\/j.clbc.2013.08.009"},{"key":"10.3238\/arztebl.2018.0628_ref35","doi-asserted-by":"crossref","unstructured":"Clemens MW, Collins MS, Butler CE: Characteristics and treatment of patients with breast implant-associated anaplastic large cell lymphoma presenting with aggressive features. Plast Reconstr Surg 2015; 136: 119","DOI":"10.1097\/01.prs.0000472428.27422.0d"},{"key":"10.3238\/arztebl.2018.0628_ref36","doi-asserted-by":"crossref","unstructured":"Hapgood G, Savage KJ: The biology and management of systemic anaplastic large cell lymphoma. Blood 2015; 126: 17\u201325","DOI":"10.1182\/blood-2014-10-567461"},{"key":"10.3238\/arztebl.2018.0628_ref37","doi-asserted-by":"crossref","unstructured":"Pro B, Advani R, Brice P, et al.: Brentuximab vetodin (SGN-35) in patients with relapsed or refractory systemic anaplastic large cell lymphoma: results of a phase II study. J Clin Oncol 2012; 30: 2190\u20136","DOI":"10.1200\/JCO.2011.38.0402"},{"key":"10.3238\/arztebl.2018.0628_ref38","doi-asserted-by":"crossref","unstructured":"Johnson L, O\u00b4Donoghue JM, McLean N, et al.: Breast implant associated anaplastic large cell lymphoma: the UK experience. Recommendations on its management and implications for informed consent. Eur J Surg Oncol 2017; 43: 1393\u2013401","DOI":"10.1016\/j.ejso.2017.05.004"}],"container-title":["Deutsches \u00c4rzteblatt international"],"original-title":[],"link":[{"URL":"https:\/\/www.aerzteblatt.de\/10.3238\/arztebl.2018.0628","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T14:00:48Z","timestamp":1638799248000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aerzteblatt.de\/10.3238\/arztebl.2018.0628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,21]]},"references-count":38,"URL":"https:\/\/doi.org\/10.3238\/arztebl.2018.0628","relation":{},"ISSN":["1866-0452"],"issn-type":[{"value":"1866-0452","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,21]]}}}