{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:32:28Z","timestamp":1761611548530},"reference-count":25,"publisher":"Deutscher Arzte-Verlag GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.3238\/arztebl.m2022.0287","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T12:04:06Z","timestamp":1658923446000},"source":"Crossref","is-referenced-by-count":12,"title":["Monkeypox in Germany"],"prefix":"10.3238","author":[{"given":"Christian","family":"Hoffmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heiko","family":"Jessen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Wyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Noe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kreckel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siegfried","family":"K\u00f6ppe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja-Sophie","family":"Krauss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Schuler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Bickel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Lenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Scholten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerd","family":"Klausen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harm-Henning","family":"Lindhof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Glaunsinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramona","family":"Pauli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"H\u00e4rter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Billy","family":"Radke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Unger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Marquardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Masuhr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Esser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim Oliver","family":"Flettner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph D.","family":"Spinner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Boesecke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11437","published-online":{"date-parts":[[2022,8,22]]},"reference":[{"key":"10.3238\/arztebl.m2022.0287_ref1","unstructured":"Ladnyj ID, Ziegler P, Kima E: A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo. Bull World Health Organ 1972; 46: 593\u20137."},{"key":"10.3238\/arztebl.m2022.0287_ref2","doi-asserted-by":"crossref","unstructured":"Simpson K, Heymann D, Brown CS, et al.: Human monkeypox\u2014after 40 years, an unintended consequence of smallpox eradication. Vaccine 2020; 38: 5077\u201381","DOI":"10.1016\/j.vaccine.2020.04.062"},{"key":"10.3238\/arztebl.m2022.0287_ref3","doi-asserted-by":"crossref","unstructured":"Minhaj FS, Ogale YP, Whitehill F, et al.: Monkeypox outbreak\u2014nine states. MMWR Morb Mortal Wkly Rep 2022; 71: 764\u20139","DOI":"10.15585\/mmwr.mm7123e1"},{"key":"10.3238\/arztebl.m2022.0287_ref4","doi-asserted-by":"crossref","unstructured":"Noe S, Zange S, Seilmaier M, et al.: Clinical and virological features of first human monkeypox cases in Germany. Infection 2022; 1\u20136.","DOI":"10.1007\/s15010-022-01874-z"},{"key":"10.3238\/arztebl.m2022.0287_ref5","unstructured":"Robert-Koch-Institut: Internationaler Affenpocken-Ausbruch: Fallzahlen und Einsch\u00e4tzung der Situation in Deutschland. Stand: 17.6.2022. https:\/\/www.rki.de\/DE\/Content\/InfAZ\/A\/Affenpocken\/Ausbruch-2022-Situation-Deutschland.html (last accessed on 20 July 2022)."},{"key":"10.3238\/arztebl.m2022.0287_ref6","doi-asserted-by":"crossref","unstructured":"Giorgi FM, Pozzobon D, Di Meglio A, Mercatelli D: Genomic analysis of the recent monkeypox outbreak. bioRxiv 2022. 06.01.494368.","DOI":"10.1101\/2022.06.01.494368"},{"key":"10.3238\/arztebl.m2022.0287_ref7","doi-asserted-by":"crossref","unstructured":"Gigante CM, Korber B, Seabolt MH, et al.: Multiple lineages of monkeypox virus detected in the United States, 2021\u20132022. bioRxiv 2022. 06.10.495526.","DOI":"10.1101\/2022.06.10.495526"},{"key":"10.3238\/arztebl.m2022.0287_ref8","doi-asserted-by":"crossref","unstructured":"Isidro J, Borges V, Pinto M, et al.: Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus. Nat Med 2022.","DOI":"10.1038\/s41591-022-01907-y"},{"key":"10.3238\/arztebl.m2022.0287_ref9","doi-asserted-by":"crossref","unstructured":"Likos AM, Sammons SA, Olson VA, et al.: A tale of two clades: monkeypox viruses. J Gen Virol 2005; 86: 2661\u201372","DOI":"10.1099\/vir.0.81215-0"},{"key":"10.3238\/arztebl.m2022.0287_ref10","doi-asserted-by":"crossref","unstructured":"Chen N, Li G, Liszewski MK, Atkinson JP, et al.: Virulence differences between monkeypox virus isolates from West Africa and the Congo basin. Virology 2005; 340: 46\u201363","DOI":"10.1016\/j.virol.2005.05.030"},{"key":"10.3238\/arztebl.m2022.0287_ref11","doi-asserted-by":"crossref","unstructured":"Yinka-Ogunleye A, Aruna O, Dalhat M, et al.: Outbreak of human monkeypox in Nigeria in 2017\u201318: a clinical and epidemiological report. Lancet Infect Dis 2019; 19: 872\u20139","DOI":"10.1016\/S1473-3099(19)30294-4"},{"key":"10.3238\/arztebl.m2022.0287_ref12","doi-asserted-by":"crossref","unstructured":"Huhn GD, Bauer AM, Yorita K, et al.: Clinical characteristics of human monkeypox, and risk factors for severe disease. Clin Infect Dis 2005; 41: 1742\u201351","DOI":"10.1086\/498115"},{"key":"10.3238\/arztebl.m2022.0287_ref13","unstructured":"UNAIDS: UNAIDS warns that stigmatizing language on monkeypox jeopardises public health. https:\/\/www.unaids.org\/en\/resources\/presscentre\/pressreleaseandstatementarchive\/2022\/may\/20220522_PR_MONKEYPOX (last accessed on 17 June 2022)."},{"key":"10.3238\/arztebl.m2022.0287_ref14","doi-asserted-by":"crossref","unstructured":"Hammarlund E, Lewis MW, Carter SV, et al.: Multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypox. Nat Med 2005; 11: 1005\u201311","DOI":"10.1038\/nm1273"},{"key":"10.3238\/arztebl.m2022.0287_ref15","doi-asserted-by":"crossref","unstructured":"Karem KL, Reynolds M, Hughes C, et al.: Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection. Clin Vaccine Immunol 2007; 14: 1318\u201327","DOI":"10.1128\/CVI.00148-07"},{"key":"10.3238\/arztebl.m2022.0287_ref16","doi-asserted-by":"crossref","unstructured":"Gilchuk I, Gilchuk P, Sapparapu G, et al.: Cross-neutralizing and protective human antibody specificities to poxvirus infections. Cell 2016, 167: 684\u201394.","DOI":"10.1016\/j.cell.2016.09.049"},{"key":"10.3238\/arztebl.m2022.0287_ref17","doi-asserted-by":"crossref","unstructured":"Fine PE, Zezek Z, Grab B, Dixon H: The transmission potential of monkeypox virus in human populations. Int J Epidemiol 1988; 17: 643\u201350","DOI":"10.1093\/ije\/17.3.643"},{"key":"10.3238\/arztebl.m2022.0287_ref18","doi-asserted-by":"crossref","unstructured":"Rimoin AW, Mulembakani PM, Johnston SC, Lloyd Smith JO, Kisalu NK, Kinkela TL: Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo. Proc Natl Acad Sci USA 2010; 107: 16262\u20137","DOI":"10.1073\/pnas.1005769107"},{"key":"10.3238\/arztebl.m2022.0287_ref19","doi-asserted-by":"crossref","unstructured":"Petersen E, Abubakar I, Ihekweazu C, Heymann D, Ntoumi F, Blumberg L: Monkeypox\u2014enhancing public health preparedness for an emerging lethal human zoonotic epidemic threat in the wake of the smallpox post-eradication era. Int J Infect Dis 2019; 78: 78\u201384","DOI":"10.1016\/j.ijid.2018.11.008"},{"key":"10.3238\/arztebl.m2022.0287_ref20","doi-asserted-by":"crossref","unstructured":"Rao AK, Petersen BW, Whitehill F, et al.: Use of JYNNEOS (smallpox and monkeypox vaccine, live, nonreplicating) for preexposure vaccination of persons at risk for occupational exposure to orthopoxviruses: recommendations of the Advisory Committee on Immunization Practices\u2014United States, 2022. MMWR Morb Mortal Wkly Rep 2022, 71: 734\u201342.","DOI":"10.15585\/mmwr.mm7122e1"},{"key":"10.3238\/arztebl.m2022.0287_ref21","unstructured":"Imvanex, Fachinformation: https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/imvanex-epar-product-information_de.pdf (last accessed on 20 July 2022)."},{"key":"10.3238\/arztebl.m2022.0287_ref22","doi-asserted-by":"crossref","unstructured":"Edghill-Smith Y, Bray M, Whitehouse CA, et al.: Smallpox vaccine does not protect macaques with AIDS from a lethal monkeypox virus challenge. J Infect Dis 2005; 191: 372\u201381","DOI":"10.1086\/427265"},{"key":"10.3238\/arztebl.m2022.0287_ref23","doi-asserted-by":"crossref","unstructured":"Fleischauer AT, Kile JC, Davidson M, et al.: Evaluation of human-to-human transmission of monkeypox from infected patients to health care workers. Clin Infect Dis 2005; 40: 689\u201394","DOI":"10.1086\/427805"},{"key":"10.3238\/arztebl.m2022.0287_ref24","doi-asserted-by":"crossref","unstructured":"Vaughan A, Aarons E, Astbury J, et al.: Human-to-human transmission of monkeypox virus, United Kingdom, October 2018. Emerg Infect Dis 2020; 26: 782\u20135","DOI":"10.3201\/eid2604.191164"},{"key":"10.3238\/arztebl.m2022.0287_ref25","unstructured":"Adler H, Gould S, Hine P, et al.: NHS England high consequence infectious diseases (airborne) network. Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis 2022, 22: 1473\u20133099."}],"container-title":["Deutsches \u00c4rzteblatt international"],"original-title":[],"link":[{"URL":"https:\/\/www.aerzteblatt.de\/10.3238\/arztebl.m2022.0287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T09:10:35Z","timestamp":1660122635000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aerzteblatt.de\/10.3238\/arztebl.m2022.0287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,22]]},"references-count":25,"URL":"https:\/\/doi.org\/10.3238\/arztebl.m2022.0287","relation":{},"ISSN":["1866-0452"],"issn-type":[{"value":"1866-0452","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,22]]}}}