{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:09:56Z","timestamp":1792548596998,"version":"4.5.0"},"reference-count":17,"publisher":"Deutscher Arzte-Verlag GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.3238\/arztebl.m2025.0066","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T09:35:33Z","timestamp":1747820133000},"source":"Crossref","is-referenced-by-count":7,"title":["A smartphone-guided digital health application for hypertension: The randomized controlled HELP trial"],"prefix":"10.3238","author":[{"given":"Andreas","family":"Zietzer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"D\u00fcsing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Brokamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Stieber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Zgouras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan H.","family":"Schirmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11437","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"10.3238\/arztebl.m2025.0066_ref1","unstructured":"Murray CJL, Aravkin AY, Zheng P, et al.: Global burden of 87 risk factors in 204 countries and territories, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019. Lancet 2020; 396: 1223–49."},{"key":"10.3238\/arztebl.m2025.0066_ref2","doi-asserted-by":"crossref","unstructured":"Oparil S, Acelajado MC, Bakris GL, et al.: Hypertension. Nat Rev Dis Primer 2018; 4: 18014.","DOI":"10.1038\/nrdp.2018.14"},{"key":"10.3238\/arztebl.m2025.0066_ref3","doi-asserted-by":"crossref","unstructured":"McEvoy JW, McCarthy CP, Bruno RM, et al.: 2024 ESC Guidelines for the management of elevated blood pressure and hypertension. What is new in pharmacotherapy? Eur Heart J Cardiovasc Pharmacother 2025; 11: 7–9.","DOI":"10.1093\/ehjcvp\/pvae084"},{"key":"10.3238\/arztebl.m2025.0066_ref4","unstructured":"Arzneimittelkommission der Deutschen Apotheker (AMK), Arzneimittelkommission der Deutschen \u00c4rzteschaft (Akd\u00c4), Deutsche Arbeitsgemeinschaft Selbsthilfegruppen e. V. (DAG SHG), et al.: NVL Hypertonie—Langfassung. Bundes\u00e4rztekammer (B\u00c4K); Kassen\u00e4rztliche Bundesvereinigung (KBV); Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) 2023."},{"key":"10.3238\/arztebl.m2025.0066_ref5","doi-asserted-by":"crossref","unstructured":"Burnier M, Egan BM: Adherence in hypertension: A review of prevalence, risk factors, impact, and management. Circ Res 2019; 124: 1124–40.","DOI":"10.1161\/CIRCRESAHA.118.313220"},{"key":"10.3238\/arztebl.m2025.0066_ref6","unstructured":"Mazzolai L, Teixido-Tura G, Lanzi S, et al.: 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases. Eur Heart J 2024; 45: 3538–700."},{"key":"10.3238\/arztebl.m2025.0066_ref7","unstructured":"Vrints C, Andreotti F, Koskinas KC, et al.: 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J 2024; 45: 3415–537."},{"key":"10.3238\/arztebl.m2025.0066_ref8","doi-asserted-by":"crossref","unstructured":"Gandhi S, Chen S, Hong L, et al.: Effect of mobile health interventions on the secondary prevention of cardiovascular disease: Systematic review and meta-analysis. Can J Cardiol 2017; 33: 219–31.","DOI":"10.1016\/j.cjca.2016.08.017"},{"key":"10.3238\/arztebl.m2025.0066_ref9","doi-asserted-by":"crossref","unstructured":"Yun YH, Kang E, Cho YM, et al.: Efficacy of an electronic health management program for patients with cardiovascular risk: Randomized controlled trial. J Med Internet Res 2020; 22: e15057.","DOI":"10.2196\/15057"},{"key":"10.3238\/arztebl.m2025.0066_ref10","doi-asserted-by":"crossref","unstructured":"Gallagher R, Chow CK, Parker H, et al.: The effect of a game-based mobile app ‘MyHeartMate’ to promote lifestyle change in coronary disease patients: A randomized controlled trial. Eur Heart J Digit Health 2023; 4: 33–42.","DOI":"10.1093\/ehjdh\/ztac069"},{"key":"10.3238\/arztebl.m2025.0066_ref11","unstructured":"Mancia G, Kreutz R, Brunstr\u00f6m M, et al.: 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). J Hypertens 2023; 41: 1874–2071."},{"key":"10.3238\/arztebl.m2025.0066_ref12","doi-asserted-by":"crossref","unstructured":"D\u00fcsing P, Eckardt I, Schirmer SH, et al.: A prospective, randomized, controlled, multicentre trial for secondary prevention in patients with chronic coronary syndrome using a smartphone application for digital therapy: the CHANGE study protocol. Eur Heart J Digit Health 2023; 4: 207–15.","DOI":"10.1093\/ehjdh\/ztad012"},{"key":"10.3238\/arztebl.m2025.0066_ref13","doi-asserted-by":"crossref","unstructured":"D\u00fcsing P, Schirmer SH, Sch\u00e4fer S, et al.: A smartphone-guided secondary prevention digital health application reduces systolic blood pressure in patients with chronic coronary syndrome and insufficient blood pressure control. Front Cardiovasc Med 2025; 12: 1515598.","DOI":"10.3389\/fcvm.2025.1515598"},{"key":"10.3238\/arztebl.m2025.0066_ref14","doi-asserted-by":"crossref","unstructured":"Law MR, Morris JK, Wald NJ: Use of blood pressure lowering drugs in the prevention of cardiovascular disease: Meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. BMJ 2009; 338: b1665.","DOI":"10.1136\/bmj.b1665"},{"key":"10.3238\/arztebl.m2025.0066_ref15","doi-asserted-by":"crossref","unstructured":"Patel HC, Hayward C, Ozdemir BA, et al.: Magnitude of blood pressure reduction in the placebo arms of modern hypertension trials: implications for trials of renal denervation. Hypertension 2015; 65: 401–6.","DOI":"10.1161\/HYPERTENSIONAHA.114.04640"},{"key":"10.3238\/arztebl.m2025.0066_ref16","doi-asserted-by":"crossref","unstructured":"Stergiou GS, Palatini P, Parati G, et al.: 2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement. J Hypertens 2021; 39: 1293–302.","DOI":"10.1097\/HJH.0000000000002843"},{"key":"10.3238\/arztebl.m2025.0066_ref17","doi-asserted-by":"crossref","unstructured":"Dickson VV, Lee C, Yehle KS, Abel WM, Riegel B: Psychometric testing of the self-care of hypertension inventory. J Cardiovasc Nurs 2017; 32: 431–8.","DOI":"10.1097\/JCN.0000000000000364"}],"container-title":["Deutsches \u00c4rzteblatt international"],"original-title":[],"link":[{"URL":"https:\/\/www.aerzteblatt.de\/10.3238\/arztebl.m2025.0066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T09:35:44Z","timestamp":1747820144000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aerzteblatt.de\/10.3238\/arztebl.m2025.0066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,30]]},"references-count":17,"URL":"https:\/\/doi.org\/10.3238\/arztebl.m2025.0066","relation":{},"ISSN":["1866-0452"],"issn-type":[{"value":"1866-0452","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,30]]}}}