{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T09:11:44Z","timestamp":1709889104786},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Przegl Epidemiol"],"abstract":"<p><strong>ABSTRACT<\/strong><br \/><strong>INTRODUCTION.<\/strong> Influenza is an acute infectious disease caused by an RNA virus. In Poland, influenza\u00a0occurs seasonally during the epidemic period lasting from October to April. The peak of influenza incidence in\u00a0Poland falls in the first quarter of the year, with a comparable number of cases in January, February and March.\u00a0Influenza can be severe in some patients, requiring hospitalization, or even fatal, especially in high-risk patients.<br \/><strong>OBJECTIVE.<\/strong> Analysis of the frequency and course of influenza in primary care patients compared to other\u00a0respiratory tract infections.<br \/><strong>MATERIAL AND METHODS.<\/strong> The study included a group of 631 adult patients with symptoms of respiratory\u00a0infection who saw their GP (general practitioner) in the period from December 2018 to April 2020. Patients\u00a0reporting symptoms of respiratory tract infection were included in the study. Special attention was paid to\u00a0influenza-like symptoms, i.e. sudden onset fever and \u2265 1 respiratory clinical symptom such as cough, sore throat,\u00a0rhinitis or feeling of stuffy nose and \u2265 1 systemic symptom such as headache, muscle pain, sweating or chills,\u00a0fatigue persisting < 72 h. Rapid antigen tests were performed in case of influenza-like symptoms. Influenza\u00a0was diagnosed in patients with the above symptoms and a positive antigen test. In the study group, 356 rapid\u00a0flu tests were performed. Age, comorbidities, nicotinism, vaccination status, clinical symptoms, ordered x-rays,\u00a0laboratory tests, the result of the Actim Influenza A&B rapid antigen test (Medix Biochemica) for influenza\u00a0virus infection, and the final diagnosis were taken into account.<br \/><strong>RESULTS.<\/strong> Influenza was diagnosed in 91 patients (in one person on the basis of clinical symptoms, without\u00a0confirmation with a rapid antigen test), including 50 women and 41 men. The mean age of the patients was 47\u00a0years, the age range was 22-89 years. In 90 patients the infection with the influenza virus was confirmed with\u00a0the Actim Influenza A&B test (Medix Biochemica). One patient was diagnosed with influenza on the basis\u00a0of typical clinical symptoms, despite a negative antigen test, and prior contact with a person with confirmed\u00a0influenza.<br \/>Fever, cough, myalgia, tachypnoea, chest pain and reported respiratory disturbances, confirmed by abnormal\u00a0results of physical examination, were more frequent in patients with symptoms of influenza and a positive antigen\u00a0test than in other infections. Influenza was significantly more often observed in patients with impaired glucose\u00a0tolerance, atherosclerosis, and muscle diseases. Influenza was mainly diagnosed in unvaccinated patients.<\/p>\n<p><strong>STRESZCZENIE<\/strong><br \/><strong>WST\u0118P.<\/strong> Grypa jest ostr\u0105 choroba zaka\u017an\u0105 wywo\u0142ywana przez wirus RNA. W Polsce grypa wyst\u0119puje sezonowo\u00a0w okresie epidemicznym trwaj\u0105cym od pa\u017adziernika do kwietnia. Szczyt zachorowa\u0144 na gryp\u0119 w Polsce\u00a0przypada na pierwszy kwarta\u0142 roku, z por\u00f3wnywaln\u0105 liczb\u0105 przypadk\u00f3w w styczniu, lutym i marcu. Grypa\u00a0mo\u017ce mie\u0107 u niekt\u00f3rych pacjent\u00f3w przebieg ci\u0119\u017cki, wymagaj\u0105cy hospitalizacji, a nawet \u015bmiertelny, zw\u0142aszcza\u00a0w grupie pacjent\u00f3w wysokiego ryzyka.<br \/><strong>CEL.<\/strong> Analiza cz\u0119sto\u015bci wyst\u0119powania oraz przebiegu grypy u pacjent\u00f3w podstawowej opieki zdrowotnej na tle\u00a0innych zaka\u017ce\u0144 dr\u00f3g oddechowych.<br \/><strong>MATERIA\u0141 I METODY.<\/strong> Badaniem obj\u0119to grup\u0119 631 doros\u0142ych pacjent\u00f3w z objawami infekcji dr\u00f3g oddechowych,\u00a0kt\u00f3rzy zg\u0142osili si\u0119 do lekarza rodzinnego w okresie od grudnia 2018 do kwietnia 2020 roku. Do badania\u00a0kwalifikowano pacjent\u00f3w zg\u0142aszaj\u0105cych objawy infekcji dr\u00f3g oddechowych. Zwracano szczeg\u00f3ln\u0105 uwag\u0119 na\u00a0objawy przypominaj\u0105ce gryp\u0119 tj. gor\u0105czk\u0119 o nag\u0142ym pocz\u0105tku oraz \u2265 1 objaw kliniczny ze strony uk\u0142adu oddechowego,\u00a0taki jak kaszel, b\u00f3l gard\u0142a, nie\u017cyt nosa lub uczycie zatkania nosa oraz \u2265 1 objaw og\u00f3lnoustrojowy,\u00a0taki jak b\u00f3l g\u0142owy i mi\u0119\u015bni, poty lub dreszcze, zm\u0119czenie utrzymuj\u0105ce si\u0119 < 72 h. W przypadku wyst\u0119powania\u00a0objaw\u00f3w przypominaj\u0105cych gryp\u0119 przeprowadzano szybki test antygenowy. U pacjent\u00f3w z powy\u017cszymi objawami\u00a0oraz dodatnim testem antygenowym rozpoznawano gryp\u0119.<br \/>W badanej grupie wykonano 356 szybkich test\u00f3w w kierunku grypy. Uwzgl\u0119dniono wiek, wyst\u0119puj\u0105ce choroby\u00a0wsp\u00f3\u0142istniej\u0105ce, nikotynizm, status szczepie\u0144, objawy kliniczne, zlecone badania radiologiczne, badania\u00a0laboratoryjne, wynik szybkiego testu antygenowego Actim Influenza A&B (Medix Biochemica) w kierunku\u00a0zaka\u017cenia wirusem grypy, postawione rozpoznanie ko\u0144cowe.<br \/><strong>WYNIKI.<\/strong> Gryp\u0119 rozpoznano u 91 pacjent\u00f3w (u 1 osoby na podstawie objaw\u00f3w klinicznych, bez potwierdzenia\u00a0szybkim testem antygenowym) w tym u 50 kobiet i 41 m\u0119\u017cczyzn. \u015arednia wieku pacjent\u00f3w to 47 lat, zakres\u00a0wieku 22-89 lat. U 90 os\u00f3b potwierdzono zaka\u017cenie wirusem grypy testem Actim Influenza A&B (Medix Biochemica).\u00a0U 1 pacjenta rozpoznano gryp\u0119 na podstawie typowych objaw\u00f3w klinicznych oraz wcze\u015bniejszego\u00a0kontaktu z osob\u0105 z potwierdzon\u0105 gryp\u0105 pomimo ujemnego testu antygenowego.<br \/>U pacjent\u00f3w z objawami grypy i dodatnim testem antygenowym cz\u0119\u015bciej ni\u017c w przypadku pozosta\u0142ych infekcji\u00a0wyst\u0119powa\u0142y gor\u0105czka, kaszel, b\u00f3le mi\u0119\u015bniowe, tachypnoe, b\u00f3le w klatce piersiowej oraz zg\u0142aszane zaburzenia\u00a0oddychania, potwierdzane odchyleniami w badaniu przedmiotowym. Gryp\u0119 istotnie cz\u0119\u015bciej obserwowano\u00a0u pacjent\u00f3w z upo\u015bledzon\u0105 tolerancj\u0105 glukozy, mia\u017cd\u017cyc\u0105, chorobami mi\u0119\u015bni. Gryp\u0119 rozpoznawano g\u0142\u00f3wnie\u00a0u pacjent\u00f3w niezaszczepionych.<\/p><\/jats:p>","DOI":"10.32394\/pe.75.15","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T13:42:38Z","timestamp":1635169358000},"page":"159-174","source":"Crossref","is-referenced-by-count":2,"title":["The clinical picture of influenza against other respiratory tract infections in a general practitioner practice"],"prefix":"10.32394","volume":"75","author":[{"given":"A","family":"Rzepka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Mania","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17323","published-online":{"date-parts":[[2021,10,15]]},"container-title":["Przeglad Epidemiologiczny"],"original-title":["Obraz kliniczny grypy na tle innych zaka\u017ce\u0144 dr\u00f3g oddechowych w gabinecie lekarza rodzinnego"],"link":[{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-180997-101558","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-180997-101558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T08:44:54Z","timestamp":1709887494000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/The-clinical-picture-of-influenza-against-other-respiratory-tract-infections-in-a,180997,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,15]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"alternative-id":["180997"],"URL":"https:\/\/doi.org\/10.32394\/pe.75.15","relation":{},"ISSN":["0033-2100","2545-1898"],"issn-type":[{"value":"0033-2100","type":"print"},{"value":"2545-1898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,15]]}}}