{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T11:59:33Z","timestamp":1715255973476},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Przegl Epidemiol"],"abstract":"<p><strong>ABSTRACT<\/strong><br \/>Monkeypox is a viral, zoonotic, emerging infectious disease that has become the most significant orthopoxviral\u00a0infection among humans since the eradication of smallpox. It is endemic in Central and West Africa, and since\u00a0May 2022 it has caused a multi-country outbreak in six continents. So far, no clinical cases of this disease have\u00a0been observed in Poland. Monkeypox can be transmitted by any person, regardless of gender identity or sexual\u00a0preferences, through direct contact with the secretion from skin lesions or through fomites contaminated with\u00a0infectious material. Therefore, people infected with the monkeypox virus require isolation until the skin lesions\u00a0heal completely and the scabs fall off, which is equivalent to the end of their infectivity. The paper presents\u00a0a study of the first nine clinical cases of monkeypox in Poland, along with photographic documentation. All\u00a0patients were young men, the vast majority of whom had contact with multiple sexual partners, and presented\u00a0a higher prevalence of human immunodeficiency virus (HIV) infection than\u00a0 in the general population. The\u00a0course of the disease was self-limited and no specific antiviral treatment was required by any of the patients.<br \/>Nonetheless, there was a change in the route of transmission of the infection to sexual contact and an atypical\u00a0clinical course of the disease, which resulted both in skin lesions initially appearing in the anogenital area, skin\u00a0lesions occurring at various stages of development, and the appearance of skin lesions before the onset of general\u00a0symptoms. In one of the patients, skin changes were not observed at all.<\/p>\n<p><strong>STRESZCZENIE<\/strong><br \/>Ospa ma\u0142pia jest wirusow\u0105, odzwierz\u0119c\u0105, nowo pojawiaj\u0105ca si\u0119 chorob\u0105 zaka\u017an\u0105, kt\u00f3ra od eradykacji ospy\u00a0prawdziwej sta\u0142a si\u0119 najbardziej znacz\u0105c\u0105 infekcj\u0105 ortopokswirusow\u0105 w\u015br\u00f3d ludzi. Ospa ma\u0142pia wyst\u0119puje endemicznie\u00a0w Afryce Centralnej i Zachodniej, a od maja 2022 roku raportuje si\u0119 zachorowania w kilkudziesi\u0119ciu\u00a0krajach na sze\u015bciu kontynentach. Do tej pory nie obserwowano przypadk\u00f3w klinicznych tej choroby w Polsce.<br \/>Osp\u0105 ma\u0142pi\u0105 mo\u017ce zakazi\u0107 si\u0119 ka\u017cda osoba, bez wzgl\u0119du na p\u0142e\u0107 czy preferencje seksualne, poprzez kontakt\u00a0bezpo\u015bredni z wydzielin\u0105 pochodz\u0105c\u0105 ze zmian sk\u00f3rnych lub poprzez przedmioty zanieczyszczone materia\u0142em\u00a0zaka\u017anym. W zwi\u0105zku z tym osoby zaka\u017cone wirusem ospy ma\u0142piej wymagaj\u0105 izolacji do momentu ca\u0142kowitego\u00a0wygojenia si\u0119 zmian sk\u00f3rnych i odpadni\u0119cia strup\u00f3w, co jest r\u00f3wnoznaczne z zako\u0144czeniem ich zaka\u017ano\u015bci.<br \/>W pracy przedstawiono studium pierwszych dziewi\u0119ciu przypadk\u00f3w klinicznych ospy ma\u0142piej w Polsce wraz\u00a0z dokumentacj\u0105 zdj\u0119ciow\u0105. Wszyscy pacjenci byli m\u0142odymi m\u0119\u017cczyznami, kt\u00f3rzy w zdecydowanej wi\u0119kszo\u015bci\u00a0deklarowali kontakty z licznymi partnerami seksualnymi i prezentowali wy\u017csz\u0105 ni\u017c w populacji og\u00f3lnej\u00a0prewalencj\u0119 zaka\u017cenia ludzkim wirusem upo\u015bledzenia odporno\u015bci (HIV). Przebieg choroby mia\u0142 charakter samoograniczaj\u0105cy i \u017caden z pacjent\u00f3w nie wymaga\u0142 specyficznego leczenia przeciwwirusowego. Na podstawie\u00a0zebranego wywiadu ustalono przenoszenie zaka\u017cenia drog\u0105 kontakt\u00f3w seksualnych, jak r\u00f3wnie\u017c nietypowy\u00a0przebieg kliniczny choroby pod postaci\u0105 zmian sk\u00f3rnych pojawiaj\u0105cych si\u0119 pocz\u0105tkowo w okolicy anogenitalnej,\u00a0zmian sk\u00f3rnych wyst\u0119puj\u0105cych w r\u00f3\u017cnych stadiach rozwoju czy te\u017c pojawienie si\u0119 zmian sk\u00f3rnych przed\u00a0wyst\u0105pieniem objaw\u00f3w og\u00f3lnych. U jednego z pacjent\u00f3w nie zaobserwowano wyst\u0105pienia zmian sk\u00f3rnych.<\/p><\/jats:p>","DOI":"10.32394\/pe.76.17","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T13:29:04Z","timestamp":1666704544000},"page":"168-183","source":"Crossref","is-referenced-by-count":1,"title":["Study of the first clinical cases on monkeypox in Poland"],"prefix":"10.32394","volume":"76","author":[{"given":"J","family":"Kowalski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Cholewi\u0144ska-Szyma\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Cielniak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Wasilewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Bie\u0144kowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Suchacz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Dyda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17323","published-online":{"date-parts":[[2022,10,25]]},"container-title":["Przeglad Epidemiologiczny"],"original-title":["Studium pierwszych przypadk\u00f3w klinicznych ospy ma\u0142piej w Polsce"],"link":[{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-181062-101623","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-181062-101623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T08:43:55Z","timestamp":1709887435000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/Study-of-the-first-clinical-cases-on-monkeypox-in-Poland,181062,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,25]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"alternative-id":["181062"],"URL":"https:\/\/doi.org\/10.32394\/pe.76.17","relation":{},"ISSN":["0033-2100","2545-1898"],"issn-type":[{"value":"0033-2100","type":"print"},{"value":"2545-1898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,25]]}}}