{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T09:11:54Z","timestamp":1709889114778},"reference-count":0,"publisher":"National Institute of Public Health NIH (National Research Institute)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Przegl Epidemiol"],"abstract":"<jats:p>&lt;p&gt;&lt;strong&gt;ABSTRACT&lt;\/strong&gt;&lt;br \/&gt;We describe the case of tertiary syphilis involving the skin. The lesions had a nodular-ulcerative form, localized\u00a0on both arms. The patient had high titers of treponemal and non-treponemal serological tests for syphilis\u00a0and histopathological picture was indicative for nodulo-ulcerative syphilis. No cardiological, neurological or\u00a0ophtalmological abnormalities were found. The patient was treated with 2.4 million units i.m. of benzathine\u00a0benzylpenicillin three times at weekly intervals, according to European Guideline. Unfortunately, the patient\u00a0was lost for scheduled follow-up. More than two years later the skin lesions healed completely leaving discrete\u00a0scars and a four-fold decline in a titre of Venereal Disease Laboratory Test was noticed.&lt;\/p&gt;\n&lt;p&gt;&lt;strong&gt;STRESZCZENIE&lt;\/strong&gt;&lt;br \/&gt;Prezentujemy przypadek pacjenta z ki\u0142\u0105 trzeciego okresu z zaj\u0119ciem sk\u00f3ry pod postaci\u0105 ki\u0142y guzkowo-wrzodziej\u0105cej\u00a0w obr\u0119bie ko\u0144czyn g\u00f3rnych. Chory mia\u0142 wysokie miana odczyn\u00f3w kr\u0119tkowych i niekr\u0119tkowych i obraz\u00a0mikroskopowy typowy dla tej postaci ki\u0142y. Pacjent otrzyma\u0142 trzy dawki benzylpenicyliny benzatynowej,\u00a0ka\u017cda po 2,4 mln j. w odst\u0119pach tygodniowych, zgodnie z Zaleceniami Europejskimi. Niestety, nie zg\u0142osi\u0142 si\u0119\u00a0do \u017cadnej z wyznaczonych wizyt kontrolnych. Po ponad dw\u00f3ch latach stwierdzono ca\u0142kowite wygojenie zmian\u00a0sk\u00f3rnych z pozostawieniem dyskretnych blizn oraz 4-krotny spadek miana odczynu VDRL.&lt;\/p&gt;<\/jats:p>","DOI":"10.32394\/pe.76.18","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T13:29:07Z","timestamp":1666704547000},"page":"184-189","source":"Crossref","is-referenced-by-count":0,"title":["Nodulo-ulcerative syphilis \u2013 case report and the review of literature"],"prefix":"10.32394","volume":"76","author":[{"given":"U","family":"Skiepko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AB","family":"Serwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Pi\u0142asewicz-Puza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Flisiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17323","published-online":{"date-parts":[[2022,10,25]]},"container-title":["Przeglad Epidemiologiczny"],"original-title":["Ki\u0142a guzkowo-pe\u0142zakowata (guzkowo-wrzodziej\u0105ca) \u2013 opis przypadku i przegl\u0105d pi\u015bmiennictwa"],"link":[{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-181063-101624","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/pdf-181063-101624","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T08:43:56Z","timestamp":1709887436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.przeglepidemiol.pzh.gov.pl\/Nodulo-ulcerative-syphilis-case-report-and-the-review-of-literature,181063,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,25]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"alternative-id":["181063"],"URL":"https:\/\/doi.org\/10.32394\/pe.76.18","relation":{},"ISSN":["0033-2100","2545-1898"],"issn-type":[{"value":"0033-2100","type":"print"},{"value":"2545-1898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,25]]}}}